The effect of Plasmodium falciparum Sir2a histone deacetylase on clonal and longitudinal variation in expression of the var family of virulence genes

International Journal for Parasitology

Volumn 40, Issue 1, 2010, Pages 35-43

  Merrick, Catherine J ^a   Dzikowski, Ron ^b   Imamura, Hideo ^c   Chuang, Jeffrey ^c   Deitsch, Kirk ^d   Duraisingh, Manoj T ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c BOSTON COLLEGE   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Antigenic variation; Epigenetic; Plasmodium falciparum; Silencing; Sirtuin; var

Indexed keywords

PROTOZOAL PROTEIN; SIRTUIN 2; SIRTUIN 2A; UNCLASSIFIED DRUG; VAR PROTEIN;

ANTIGEN; CLONE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC VARIATION; LONGITUDINAL GRADIENT; MALARIA; PATHOGEN; PROTIST; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS;

ANTIGENIC VARIATION; ARTICLE; CELL SURFACE; CLONAL VARIATION; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SWITCHING; NONHUMAN; PARASITE VIRULENCE; PLASMODIUM FALCIPARUM; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; UPREGULATION;

ANIMALS; ANTIGENIC VARIATION; CELLS, CULTURED; ERYTHROCYTES; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE SILENCING; GROUP III HISTONE DEACETYLASES; HISTONE DEACETYLASES; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VIRULENCE;

PLASMODIUM FALCIPARUM;

EID: 72049132916     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2009.06.012     Document Type: Article

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