Enantioselective analysis of R- and S-propafenone in plasma by HPLC applying column switching and liquid-liquid extraction

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 29, 2009, Pages 3489-3494

  Lamprecht, G ^a   Stoschitzky, K ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Column switching; Enantioselective analysis; HPLC; Liquid liquid extraction; Propafenone

Indexed keywords

ANALYSIS METHOD; AQUEOUS MEDIUM; CATION EXCHANGERS; COLUMN SWITCHING; CONCENTRATION OF; ENANTIOMERIC RATIO; ENANTIOSELECTIVE; ENANTIOSELECTIVE ANALYSIS; HPLC METHOD; LIMIT OF DETECTION; LINEAR CALIBRATION; LIQUID-LIQUID EXTRACTION; PHYSICAL EXERCISE; STRONG ACIDS;

CHIRALITY; ENANTIOMERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PLASMAS; SILICA; SOLVENT EXTRACTION; SWITCHING;

LIQUIDS;

PROPAFENONE; PROPRANOLOL;

ARTICLE; CHIRALITY; DRUG BLOOD LEVEL; DRUG STRUCTURE; ENANTIOSELECTIVITY; HEART ARRHYTHMIA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIQUID LIQUID EXTRACTION; NORMAL HUMAN; PLASMA; PRIORITY JOURNAL;

CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MOLECULAR STRUCTURE; PROPAFENONE; STEREOISOMERISM;

EID: 72049118698     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.08.024     Document Type: Article

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