Simultaneous determination of propafenone and 5-hydroxypropafenone enantiomers in plasma by chromatography on an amylose derived chiral stationary phase

Journal of Pharmaceutical and Biomedical Analysis

Volumn 20, Issue 1-2, 1999, Pages 209-216

  Pires De Abreu, Luis Renato ^a   Lanchote, Vera Lúcia ^b   Bertucci, Carlo ^c   Cesarino, Evandro José ^a   Bonato, Pierina Sueli ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Faculdade Cie Farmaceuticas R   (Brazil)

^c CNR   (Italy)

Author keywords

5 Hydroxypropafenone; Amylose derived chiral stationary phase; Enantioselective LC analysis; Propafenone

Indexed keywords

ACETYLSALICYLIC ACID; ALBENDAZOLE; AMITRIPTYLINE; ATENOLOL; BROMAZEPAM; CARBAMAZEPINE; CIMETIDINE; CLONAZEPAM; DEXAMETHASONE; DEXTROPROPOXYPHENE; DIAZEPAM; DIPYRONE; DRUG METABOLITE; FLUNITRAZEPAM; FLURAZEPAM; IMIPRAMINE; LORAZEPAM; MEBENDAZOLE; METOPROLOL; MEXILETINE; PARACETAMOL; PHENOBARBITAL; PHENYTOIN; PINDOLOL; PROPAFENONE; PROPRANOLOL; TRIAZOLAM; UNINDEXED DRUG; VALPROIC ACID; VERAPAMIL;

ACCURACY; ANALYTIC METHOD; ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG METABOLISM; ENANTIOMER; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL; STEREOSPECIFICITY;

AMYLOSE; ANTI-ARRHYTHMIA AGENTS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; METHYLENE CHLORIDE; PROPAFENONE; REPRODUCIBILITY OF RESULTS; SOLUTIONS; STEREOISOMERISM;

EID: 0033005362     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(99)00022-9     Document Type: Article

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