Simultaneous and sensitive measurement of nicotine, cotinine, trans-3′-hydroxycotinine and norcotinine in human plasma by liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 29, 2009, Pages 3537-3542

  Shakleya, Diaa M ^a   Huestis, Marilyn A ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Cotinine; LC MS MS; Nicotine; Norcotinine; Plasma; trans 3 Hydroxycotinine

Indexed keywords

AFFECTIVE PROCESS; ANALYTE CONCENTRATION; ANALYTES; COTININE; ENVIRONMENTAL EXPOSURE; EXTRACTION EFFICIENCIES; HUMAN PLASMAS; LC-MS/MS; LIMITS OF QUANTIFICATION; LINEAR RANGE; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; NEURONAL SYSTEMS; SENSITIVE MEASUREMENT; VALIDATED METHODS;

CHROMATOGRAPHIC ANALYSIS; COGNITIVE SYSTEMS; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLASMA (HUMAN); PLASMAS;

PYRIDINE;

3' HYDROXYCOTININE; BIOLOGICAL MARKER; COTININE; NICOTINE; NICOTINE DERIVATIVE; NORCOTININE; PLACEBO; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MEASUREMENT; METABOLITE; PASSIVE SMOKING; PLASMA; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; TOBACCO; TOBACCO DEPENDENCE; VALIDATION STUDY; WITHDRAWAL SYNDROME;

CHROMATOGRAPHY, LIQUID; COTININE; HUMANS; NICOTINE; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 72049118417     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.08.033     Document Type: Article

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