Lactoferrin enhances efficacy of the BCG vaccine: comparison between two inbred mice strains (C57BL/6 and BALB/c)

Tuberculosis

Volumn 89, Issue SUPPL.1, 2009, Pages

  Hwang, Shen An ^a   Arora, Ranjana ^a   Kruzel, Marian L ^a   Actor, Jeffrey K ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Adjuvant; BCG; Lactoferrin; Tuberculosis; Vaccine

Indexed keywords

BCG VACCINE; GAMMA INTERFERON; LACTOFERRIN; MYCOBACTERIUM ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; BCG VACCINATION; C57BL 6 MOUSE; CONTROLLED STUDY; FEMALE; INBRED STRAIN; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; STRAIN DIFFERENCE; TH1 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, BACTERIAL; BCG VACCINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNIZATION, SECONDARY; LACTOFERRIN; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TUBERCULOSIS, PULMONARY;

EID: 72049096356     PISSN: 14729792     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-9792(09)70012-5     Document Type: Article

References (44)

1. Andersen P., and Doherty T.M. The success and failure of BCG - implications for a novel tuberculosis vaccine. Nat Rev Microbiol 3 8 (2005) 656-662
2. Brennan M.J. The tuberculosis vaccine challenge. Tuberculosis (Edinb) 85 1-2 (2005) 7-12
3. Fine P.E. BCG: the challenge continues. Scand J Infect Dis 33 4 (2001) 243-245
4. Doherty T.M. Real world TB vaccines: clinical trials in TB-endemic regions. Vaccine 23 17-18 (2005) 2109-2114
5. Fine P.E. Herd immunity: history, theory, practice. Epidemiol Rev 15 2 (1993) 265-302
6. Zimecki M., Mazurier J., Spik G., and Kapp J.A. Human lactoferrin induces phenotypic and functional changes in murine splenic B cells. Immunology 86 1 (1995) 122-127
7. Dhennin-Duthille I., Masson M., Damiens E., Fillebeen C., Spik G., and Mazurier J. Lactoferrin upregulates the expression of CD4 antigen through the stimulation of the mitogen-activated protein kinase in the human lymphoblastic T Jurkat cell line. J Cell Biochem 79 4 (2000) 583-593
8. Spadaro M., Caorsi C., Ceruti P., Varadhachary A., Forni G., Pericle F., et al. Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells. Faseb J 22 8 (2008) 2747-2757
9. Actor J.K., Hwang S.A., Olsen M., Zimecki M., Hunter Jr. R.L., and Kruzel M.L. Lactoferrin immunomodulation of DTH response in mice. Int Immunopharmacol 2 4 (2002) 475-486
10. Curran C.S., Demick K.P., and Mansfield J.M. Lactoferrin activates macrophages via TLR4-dependent and -independent signaling pathways. Cell Immunol 242 1 (2006) 23-30
11. Sorimachi K., Akimoto K., Hattori Y., Ieiri T., and Niwa A. Activation of macrophages by lactoferrin: secretion of TNF-alpha, IL-8 and NO. Biochem Mol Biol Int 43 1 (1997) 79-87
12. Wilk K.M., Hwang S.A., and Actor J.K. Lactoferrin modulation of antigen-presenting-cell response to BCG infection. Postepy Hig Med Dosw (Online) 61 (2007) 277-282
13. Na Y.J., Han S.B., Kang J.S., Yoon Y.D., Park S.K., Kim H.M., et al. Lactoferrin works as a new LPS-binding protein in inflammatory activation of macrophages. Int Immunopharmacol 4 9 (2004) 1187-1199
14. Baveye S., Elass E., Mazurier J., Spik G., and Legrand D. Lactoferrin: a multifunctional glycoprotein involved in the modulation of the inflammatory process. Clin Chem Lab Med 37 3 (1999) 281-286
15. Hwang S.A., Kruzel M.L., and Actor J.K. Influence of bovine lactoferrin on expression of presentation molecules on BCG-infected bone marrow derived macrophages. Biochimie 91 1 (2009) 76-85
16. Hwang S.A., Wilk K.M., Bangale Y.A., Kruzel M.L., and Actor J.K. Lactoferrin modulation of IL-12 and IL-10 response from activated murine leukocytes. Med Microbiol Immunol 196 3 (2007) 171-180
17. Zimecki M., Kocieba M., and Kruzel M. Immunoregulatory activities of lactoferrin in the delayed type hypersensitivity in mice are mediated by a receptor with affinity to mannose. Immunobiology 205 1 (2002) 120-131
18. Zimecki M., and Kruzel M.L. Systemic or local co-administration of lactoferrin with sensitizing dose of antigen enhances delayed type hypersensitivity in mice. Immunol Lett 74 3 (2000) 183-188
19. Hwang S.A., Kruzel M.L., and Actor J.K. Lactoferrin augments BCG vaccine efficacy to generate T helper response and subsequent protection against challenge with virulent Mycobacterium tuberculosis. Int Immunopharmacol 5 3 (2005) 591-599
20. Hwang S.A., Wilk K.M., Budnicka M., Olsen M., Bangale Y.A., Hunter R.L., et al. Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis. Vaccine 25 37-38 (2007) 6730-6743
21. Flynn J.L., and Chan J. Immunology of tuberculosis. Annu Rev Immunol 19 (2001) 93-129
22. Rao A., and Avni O. Molecular aspects of T-cell differentiation. Br Med Bull 56 4 (2000) 969-984
23. Hwang S.A., Wilk K., Kruzel M.L., and Actor J.K. A novel recombinant human lactoferrin augments the BCG vaccine and protects alveolar integrity upon infection with Mycobacterium tuberculosis in mice. Vaccine 27 23 (2009) 3026-3034
24. Actor J.K., Olsen M., Jagannath C., and Hunter R.L. Relationship of survival, organism containment, and granuloma formation in acute murine tuberculosis. J Interferon Cytokine Res 19 10 (1999) 1183-1193
25. Watson V.E., Hill L.L., Owen-Schaub L.B., Davis D.W., McConkey D.J., Jagannath C., et al. Apoptosis in Mycobacterium tuberculosis infection in mice exhibiting varied immunopathology. J Pathol 190 2 (2000) 211-220
26. Guidry T.V., Hunter Jr. R.L., and Actor J.K. Mycobacterial glycolipid trehalose 6,6-dimycolate-induced hypersensitive granulomas: contribution of CD4+ lymphocytes. Microbiology 153 Pt 10 (2007) 3360-3369
27. Actor J.K., Breij E., Wetsel R.A., Hoffmann H., Hunter Jr. R.L., and Jagannath C. A role for complement C5 in organism containment and granulomatous response during murine tuberculosis. Scand J Immunol 53 5 (2001) 464-474
28. Medina E., and North R.J. Resistance ranking of some common inbred mouse strains to Mycobacterium tuberculosis and relationship to major histocompatibility complex haplotype and Nramp1 genotype. Immunology 93 2 (1998) 270-274
29. Medina E., and North R.J. Evidence inconsistent with a role for the Bcg gene (Nramp1) in resistance of mice to infection with virulent Mycobacterium tuberculosis. J Exp Med 183 3 (1996) 1045-1051
30. Daugelat S., Ladel C.H., and Kaufmann S.H. Impact of host genetic background on bacillus Calmette-Guerin infection in naturally susceptible mice. Immunol Lett 48 2 (1995) 153-156
31. Daugelat S., Ladel C.H., and Kaufmann S.H. Influence of mouse strain and vaccine viability on T-cell responses induced by Mycobacterium bovis bacillus Calmette-Guerin. Infect Immun 63 5 (1995) 2033-2040
32. D'Souza S., Rosseels V., Denis O., Tanghe A., De Smet N., Jurion F., et al. Improved tuberculosis DNA vaccines by formulation in cationic lipids. Infect Immun 70 7 (2002) 3681-3688
33. Castanon-Arreola M., Lopez-Vidal Y., Espitia-Pinzon C., and Hernandez-Pando R. A new vaccine against tuberculosis shows greater protection in a mouse model with progressive pulmonary tuberculosis. Tuberculosis (Edinb) 85 1-2 (2005) 115-126
34. Flynn J.L., Goldstein M.M., Triebold K.J., Sypek J., Wolf S., and Bloom B.R. IL-12 increases resistance of BALB/c mice to Mycobacterium tuberculosis infection. J Immunol 155 5 (1995) 2515-2524
35. Mittrucker H.W., Steinhoff U., Kohler A., Krause M., Lazar D., Mex P., et al. Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis. Proc Natl Acad Sci USA 104 30 (2007) 12434-12439
36. McLeod R., Buschman E., Arbuckle L.D., and Skamene E. Immunogenetics in the analysis of resistance to intracellular pathogens. Curr Opin Immunol 7 4 (1995) 539-552
37. Bohn E., Heesemann J., Ehlers S., and Autenrieth I.B. Early gamma interferon mRNA expression is associated with resistance of mice against Yersinia enterocolitica. Infect Immun 62 7 (1994) 3027-3032
38. Heinzel F.P., Sadick M.D., Holaday B.J., Coffman R.L., and Locksley R.M. Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. J Exp Med 169 1 (1989) 59-72
39. Miralles G.D., Stoeckle M.Y., McDermott D.F., Finkelman F.D., and Murray H.W. Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis. Infect Immun 62 3 (1994) 1058-1063
40. Yang X., HayGlass K.T., and Brunham R.C. Genetically determined differences in IL-10 and IFN-gamma responses correlate with clearance of Chlamydia trachomatis mouse pneumonitis infection. J Immunol 156 11 (1996) 4338-4344
41. Wakeham J., Wang J., and Xing Z. Genetically determined disparate innate and adaptive cell-mediated immune responses to pulmonary Mycobacterium bovis BCG infection in C57BL/6 and BALB/c mice. Infect Immun 68 12 (2000) 6946-6953
42. Huygen K., Abramowicz D., Vandenbussche P., Jacobs F., De Bruyn J., Kentos A., et al. Spleen cell cytokine secretion in Mycobacterium bovis BCG-infected mice. Infect Immun 60 7 (1992) 2880-2886
43. Radosevic K., Wieland C.W., Rodriguez A., Weverling G.J., Mintardjo R., Gillissen G., et al. Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon. Infect Immun 75 8 (2007) 4105-4115
44. Shibuya K., Robinson D., Zonin F., Hartley S.B., Macatonia S.E., Somoza C., et al. IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice. J Immunol 160 4 (1998) 1708-1716