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Volumn 3, Issue 3, 2009, Pages 213-218

New results from the use of bisphosphonates in cancer patients

Author keywords

Adjuvant therapy; Bisphosphonates; Bone metastases; Cancer treatment induced bone loss; Skeletal related events

Indexed keywords

ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; BONE DENSITY CONSERVATION AGENT;

EID: 72049088878     PISSN: 17514258     EISSN: 17514266     Source Type: Journal    
DOI: 10.1097/SPC.0b013e32832f4149     Document Type: Article
Times cited : (25)

References (55)
  • 1
    • 33750726077 scopus 로고    scopus 로고
    • Clinical features of metastatic bone disease and risk of skeletal morbidity
    • Coleman RE. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res 2006; 12 (20 Suppl):6243-6249.
    • (2006) Clin Cancer Res , vol.12 , Issue.20 SUPPL , pp. 6243-6249
    • Coleman, R.E.1
  • 2
    • 26944459975 scopus 로고    scopus 로고
    • Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to bone
    • Clines GA, Guise TA. Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to bone. Endocr Relat Cancer 2005; 12:549-583.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 549-583
    • Clines, G.A.1    Guise, T.A.2
  • 3
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002; 2:584-593.
    • (2002) Nat Rev Cancer , vol.2 , pp. 584-593
    • Mundy, G.R.1
  • 4
    • 46949100735 scopus 로고    scopus 로고
    • Exploring the antitumour activity of bisphosphonates in early breast cancer
    • Winter MC, Holen I, Coleman RE. Exploring the antitumour activity of bisphosphonates in early breast cancer. Cancer Treat Rev 2008; 34:453-475.
    • (2008) Cancer Treat Rev , vol.34 , pp. 453-475
    • Winter, M.C.1    Holen, I.2    Coleman, R.E.3
  • 5
    • 11144254409 scopus 로고    scopus 로고
    • Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells
    • Neville-Webbe HL, Rostami-Hodjegan A, Evans CA, et al. Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells. Int J Cancer 2005; 113:364- 371.
    • (2005) Int J Cancer , vol.113 , pp. 364-371
    • Neville-Webbe, H.L.1    Rostami-Hodjegan, A.2    Evans, C.A.3
  • 6
    • 51049114468 scopus 로고    scopus 로고
    • Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer
    • Preclinical in-vivo study indicating remarkable sequence-dependent synergy between chemotherapy and zoledronic acid
    • Ottewell PD, Monkkonen H, Jones M, et al. Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer. J Natl Cancer Inst 2008; 100:1167-1178. Preclinical in-vivo study indicating remarkable sequence-dependent synergy between chemotherapy and zoledronic acid.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1167-1178
    • Ottewell, P.D.1    Mönkkönen, H.2    Jones, M.3
  • 7
    • 69249218221 scopus 로고    scopus 로고
    • The addition of zoledronic acid to neoadjuvant chemotherapy may influence pathological response: Exploratory evidence for direct antitumor activity in breast cancer
    • abstract 5101
    • Winter MC, Thorpe HC, Burkinshaw R, et al. The addition of zoledronic acid to neoadjuvant chemotherapy may influence pathological response: exploratory evidence for direct antitumor activity in breast cancer. Cancer Res 2008; 69 (Suppl 2); abstract 5101.
    • (2008) Cancer Res , vol.69 , Issue.SUPPL 2
    • Winter, M.C.1    Thorpe, H.C.2    Burkinshaw, R.3
  • 8
    • 44349185434 scopus 로고    scopus 로고
    • Risks and benefits of bisphosphonates
    • Coleman RE. Risks and benefits of bisphosphonates. Br J Cancer 2008; 98:1736-1740.
    • (2008) Br J Cancer , vol.98 , pp. 1736-1740
    • Coleman, R.E.1
  • 9
    • 40149083563 scopus 로고    scopus 로고
    • Guidance on the use of bisphosphonates in solid tumours: Recommendations of an international expert panel
    • Consensus document on the use of bisphosphonates in malignancy. Useful practice guideline
    • Aapro M, Abrahamsson PA, Body JJ, et al. Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel. Ann Oncol 2008; 19:420-432. Consensus document on the use of bisphosphonates in malignancy. Useful practice guideline.
    • (2008) Ann Oncol , vol.19 , pp. 420-432
    • Aapro, M.1    Abrahamsson, P.A.2    Body, J.J.3
  • 10
    • 19944432878 scopus 로고    scopus 로고
    • Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors
    • Brown JE, Cook RJ, Major P, et al. Bone turnover markers as predictors of skeletal complications in prostate cancer, lung cancer, and other solid tumors. J Natl Cancer Inst 2005; 97:59-69.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 59-69
    • Brown, J.E.1    Cook, R.J.2    Major, P.3
  • 11
    • 47149118386 scopus 로고    scopus 로고
    • Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid
    • Evaluation of biochemical response to bisphosphonate treatment. Demonstrated that normalisation of bone resorption was associated with improved disease outcomes
    • Lipton A, Cook R, Saad F, et al. Normalization of bone markers is associated with improved survival in patients with bone metastases from solid tumors and elevated bone resorption receiving zoledronic acid. Cancer 2008; 113:193- 201. Evaluation of biochemical response to bisphosphonate treatment. Demonstrated that normalisation of bone resorption was associated with improved disease outcomes.
    • (2008) Cancer , vol.113 , pp. 193-201
    • Lipton, A.1    Cook, R.2    Saad, F.3
  • 12
    • 33750605957 scopus 로고    scopus 로고
    • Phase II trial evaluating the palliative benefit of second-line zoledronic acid in breast cancer patients with either a skeletal-related event or progressive bone metastases despite first-line bisphosphonate therapy
    • Clemons MJ, Dranitsaris G, Ooi WS, et al. Phase II trial evaluating the palliative benefit of second-line zoledronic acid in breast cancer patients with either a skeletal-related event or progressive bone metastases despite first-line bisphosphonate therapy. J Clin Oncol 2006; 20:4895-4900.
    • (2006) J Clin Oncol , vol.20 , pp. 4895-4900
    • Clemons, M.J.1    Dranitsaris, G.2    Ooi, W.S.3
  • 13
    • 63749094012 scopus 로고    scopus 로고
    • Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates.
    • Important proof of concept study showing ability to reverse biochemical 'resistance' with a novel osteoclast inhibitor
    • Fizazi K, Lipton A, Mariette X, et al. Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J Clin Oncol 2009; 27:1564- 1571. Important proof of concept study showing ability to reverse biochemical 'resistance' with a novel osteoclast inhibitor.
    • (2009) J Clin Oncol , vol.27 , pp. 1564-1571
    • Fizazi, K.1    Lipton, A.2    Mariette, X.3
  • 14
    • 17444401018 scopus 로고    scopus 로고
    • The causes and treatment of bone loss associated with carcinoma of the breast
    • Lester J, Dodwell D, McCloskey E, Coleman R. The causes and treatment of bone loss associated with carcinoma of the breast. Cancer Treat Rev 2005; 31:115-142.
    • (2005) Cancer Treat Rev , vol.31 , pp. 115-142
    • Lester, J.1    Dodwell, D.2    McCloskey, E.3    Coleman, R.4
  • 15
    • 44649083063 scopus 로고    scopus 로고
    • Bone loss in patients with breast cancer receiving aromatase inhibitors and associated treatment strategies
    • Coleman RE, Body J-J, Gralow JR, Lipton A. Bone loss in patients with breast cancer receiving aromatase inhibitors and associated treatment strategies. Cancer Treat Rev 2008; 34 (Suppl 1):S31-S42.
    • (2008) Cancer Treat Rev , vol.34 , Issue.SUPPL 1
    • Coleman, R.E.1    Body, J.-J.2    Gralow, J.R.3    Lipton, A.4
  • 16
    • 33846545488 scopus 로고    scopus 로고
    • Skeletal effects of exemestane on bone-mineral density, bone biomarkers, and fracture incidence in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES): A randomised controlled study
    • Coleman RE, Banks LM, Girgis SI, et al. Skeletal effects of exemestane on bone-mineral density, bone biomarkers, and fracture incidence in postmenopausal women with early breast cancer participating in the Intergroup Exemestane Study (IES): a randomised controlled study. Lancet Oncol 2007; 8:119-127.
    • (2007) Lancet Oncol , vol.8 , pp. 119-127
    • Coleman, R.E.1    Banks, L.M.2    Girgis, S.I.3
  • 17
    • 41949094767 scopus 로고    scopus 로고
    • Effect of anastrozole on bone mineral density: 5-year results from the anastrozole, tamoxifen, alone or in combination trial 18233230
    • First publication to define the bone effects of 5 years adjuvant treatment with an aromatase inhibitor
    • Eastell R, Adams JE, Coleman RE, et al. Effect of anastrozole on bone mineral density: 5-year results from the anastrozole, tamoxifen, alone or in combination trial 18233230. J Clin Oncol 2008; 26:1051-1057. First publication to define the bone effects of 5 years adjuvant treatment with an aromatase inhibitor.
    • (2008) J Clin Oncol , vol.26 , pp. 1051-1057
    • Eastell, R.1    Adams, J.E.2    Coleman, R.E.3
  • 18
    • 0029864362 scopus 로고    scopus 로고
    • Ovarian function in premenopausal women treated with adjuvant chemotherapy for breast cancer
    • Bines J, Oleske DM, Cobleigh MA. Ovarian function in premenopausal women treated with adjuvant.
    • (1996) J Clin Oncol , vol.14 , pp. 1718-1729
    • Bines, J.1    Oleske, D.M.2    Cobleigh, M.A.3
  • 19
    • 29144517438 scopus 로고    scopus 로고
    • Risk of clinical fractures after gonadotropin-releasing hormone agonist therapy for prostate cancer
    • Smith MR, Boyce SP, Moyneur E, et al. Risk of clinical fractures after gonadotropin-releasing hormone agonist therapy for prostate cancer. J Urol 2006; 175:136-139.
    • (2006) J Urol , vol.175 , pp. 136-139
    • Smith, M.R.1    Boyce, S.P.2    Moyneur, E.3
  • 20
    • 46849110780 scopus 로고    scopus 로고
    • Practical guidance for the management of aromatase inhibitor-associated bone loss
    • Useful consensus guidelines for defining management strategies for the treatment of bone loss in breast cancer
    • Hadji P, Body J-J, Aapro MS, et al. Practical guidance for the management of aromatase inhibitor-associated bone loss. Ann Oncol 2008; 19:1407- 1416. Useful consensus guidelines for defining management strategies for the treatment of bone loss in breast cancer.
    • (2008) Ann Oncol , vol.19 , pp. 1407-1416
    • Hadji, P.1    Body, J.-J.2    Aapro, M.S.3
  • 21
    • 44649187408 scopus 로고    scopus 로고
    • Guidance for the management of breast cancer treatment-induced bone loss: A consensus position statement from a UK expert group
    • UK consensus guidelines for defining management strategies for the treatment of bone loss in breast cancer
    • Reid DM, Doughty J, Eastell R, et al. Guidance for the management of breast cancer treatment-induced bone loss: a consensus position statement from a UK Expert Group. Cancer Treat Rev 2008; 34 (Suppl 1):S3-S18. UK consensus guidelines for defining management strategies for the treatment of bone loss in breast cancer.
    • (2008) Cancer Treat Rev , vol.34 , Issue.SUPPL 1
    • Reid, D.M.1    Doughty, J.2    Eastell, R.3
  • 22
    • 0035196356 scopus 로고    scopus 로고
    • Long-term impact of chemotherapyinduced ovarian failure on bone mineral density (BMD) in premenopausal breast cancer patients. The effect of adjuvant clodronate treatment
    • Vehmanen L, Saarto T, Elomaa I, et al. Long-term impact of chemotherapyinduced ovarian failure on bone mineral density (BMD) in premenopausal breast cancer patients. The effect of adjuvant clodronate treatment. Eur J Cancer 2001; 37:2373-2378.
    • (2001) Eur J Cancer , vol.37 , pp. 2373-2378
    • Vehmanen, L.1    Saarto, T.2    Elomaa, I.3
  • 23
    • 0031057249 scopus 로고    scopus 로고
    • Bisphosphonate risedronate prevents bone loss in women with artificial menopause due to chemotherapy of breast cancer: A double-blind, placebo-controlled study
    • Delmas PD, Balena R, Confravreux E, et al. Bisphosphonate risedronate prevents bone loss in women with artificial menopause due to chemotherapy of breast cancer: a double-blind, placebo-controlled study. J Clin Oncol 1997; 15:955-962.
    • (1997) J Clin Oncol , vol.15 , pp. 955-962
    • Delmas, P.D.1    Balena, R.2    Confravreux, E.3
  • 24
    • 21244494910 scopus 로고    scopus 로고
    • Pamidronate in the prevention of chemotherapy-induced bone loss in premenopausal women with breast cancer: A randomized controlled trial
    • Fuleihan Gel H, Salamoun M, Mourad YA, et al. Pamidronate in the prevention of chemotherapy-induced bone loss in premenopausal women with breast cancer: a randomized controlled trial. J Clin Endocrinol Metab 2005; 90:3209-3214.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3209-3214
    • Fuleihan, G.H.1    Salamoun, M.2    Mourad, Y.A.3
  • 25
    • 34848887818 scopus 로고    scopus 로고
    • Prolonged efficacy of a single dose of the bisphosphonate zoledronic acid
    • Brown JE, Ellis SP, Lester JE, et al. Prolonged efficacy of a single dose of the bisphosphonate zoledronic acid. Clin Cancer Res 2007; 13:5406- 5410.
    • (2007) Clin Cancer Res , vol.13 , pp. 5406-5410
    • Brown, J.E.1    Ellis, S.P.2    Lester, J.E.3
  • 26
    • 54249151531 scopus 로고    scopus 로고
    • Zoledronic acid prevents bone loss in premenopausal women undergoing adjuvant chemotherapy for earlystage breast cancer
    • Hershman DL, McMahon DJ, Crew KD, et al. Zoledronic acid prevents bone loss in premenopausal women undergoing adjuvant chemotherapy for earlystage breast cancer. J Clin Oncol 2008; 26:4739-4745.
    • (2008) J Clin Oncol , vol.26 , pp. 4739-4745
    • Hershman, D.L.1    McMahon, D.J.2    Crew, K.D.3
  • 27
    • 33947539707 scopus 로고    scopus 로고
    • Zoledronic acid prevents cancer treatment-induced bone loss in premenopausal women receiving adjuvant endocrine therapy for hormone-responsive breast cancer: A report from the Austrian Breast and Colorectal Cancer Study Group
    • Gnant M, Mlineritsch B, Luschin-Ebengreuth G, et al. Zoledronic acid prevents cancer treatment-induced bone loss in premenopausal women receiving adjuvant endocrine therapy for hormone-responsive breast cancer: a report from the Austrian Breast and Colorectal Cancer Study Group. J Clin Oncol 2007; 25:820-828.
    • (2007) J Clin Oncol , vol.25 , pp. 820-828
    • Gnant, M.1    Mlineritsch, B.2    Luschin-Ebengreuth, G.3
  • 28
    • 49949115926 scopus 로고    scopus 로고
    • Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy
    • Important study defining the degree of bone loss from endocrine treatments including ovarian suppression for early breast cancer and protective effects of zoledronic acid. Also provides data on partial recovery of BMD on cessation of endocrine treatments
    • Gnant M, Mlineritsch B, Luschin-Ebengreuth G, et al. Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy. Lancet Oncol 2008; 9:840-849. Important study defining the degree of bone loss from endocrine treatments including ovarian suppression for early breast cancer and protective effects of zoledronic acid. Also provides data on partial recovery of BMD on cessation of endocrine treatments.
    • (2008) Lancet Oncol , vol.9 , pp. 840-849
    • Gnant, M.1    Mlineritsch, B.2    Luschin-Ebengreuth, G.3
  • 29
    • 61449227421 scopus 로고    scopus 로고
    • N02C1: A phase III randomized, placebo-controlled, double-blind trial of risedronate for prevention of bone loss in premenopausal women undergoing adjuvant chemotherapy for breast cancer
    • Provides important observation that standard osteoporosis treatment may be insufficient to prevent bone loss caused by chemotherapy induced ovarian suppression
    • Hines SL, Mincey BA, Sloan JA, et al. N02C1: a phase III randomized, placebo-controlled, double-blind trial of risedronate for prevention of bone loss in premenopausal women undergoing adjuvant chemotherapy for breast cancer. J Clin Oncol 2009; 27:1047-1053. Provides important observation that standard osteoporosis treatment may be insufficient to prevent bone loss caused by chemotherapy induced ovarian suppression.
    • (2009) J Clin Oncol , vol.27 , pp. 1047-1053
    • Hines, S.L.1    Mincey, B.A.2    Sloan, J.A.3
  • 30
    • 52049093463 scopus 로고    scopus 로고
    • Ten-year follow-up of 3 years of oral adjuvant clodronate therapy shows significant prevention of osteoporosis in early-stage breast cancer
    • Saarto T, Vehmanen L, Blomqvist C, et al. Ten-year follow-up of 3 years of oral adjuvant clodronate therapy shows significant prevention of osteoporosis in early-stage breast cancer. J Clin Oncol 2008; 26:4289-4295.
    • (2008) J Clin Oncol , vol.26 , pp. 4289-4295
    • Saarto, T.1    Vehmanen, L.2    Blomqvist, C.3
  • 31
    • 34547569748 scopus 로고    scopus 로고
    • Estrogen-dependent increase in bone turnover and bone loss in postmenopausal women with breast cancer treated with anastrozole. Prevention with bisphosphonates
    • Confavreux CB, Fontana A, Guastalla JP, et al. Estrogen-dependent increase in bone turnover and bone loss in postmenopausal women with breast cancer treated with anastrozole. Prevention with bisphosphonates. Bone 2007; 41:346-352.
    • (2007) Bone , vol.41 , pp. 346-352
    • Confavreux, C.B.1    Fontana, A.2    Guastalla, J.P.3
  • 32
    • 45749127094 scopus 로고    scopus 로고
    • Risedronate prevents bone loss in breast cancer survivors: A 2-year, randomized, double-blind, placebocontrolled clinical trial
    • Study reporting on the efficacy of an osteoporosis schedule for the treatment of bone loss in postmenopausal breast cancer patients
    • Greenspan SL, Brufsky A, Lembersky BC, et al. Risedronate prevents bone loss in breast cancer survivors: a 2-year, randomized, double-blind, placebocontrolled clinical trial. J Clin Oncol 2008; 26:2644-2652. Study reporting on the efficacy of an osteoporosis schedule for the treatment of bone loss in postmenopausal breast cancer patients.
    • (2008) J Clin Oncol , vol.26 , pp. 2644-2652
    • Greenspan, S.L.1    Brufsky, A.2    Lembersky, B.C.3
  • 33
    • 58149166777 scopus 로고    scopus 로고
    • Prevention of anastrozole-induced bone loss with monthly oral ibandronate during adjuvant aromatase inhibitor therapy for breast cancer
    • First study to report the efficacy of an osteoporosis dose of ibadronate in the treatment of aromatase inhibitor induced bone loss
    • Lester JE, Dodwell D, Purohit OP, et al. Prevention of anastrozole-induced bone loss with monthly oral ibandronate during adjuvant aromatase inhibitor therapy for breast cancer. Clin Cancer Res 2008; 14:6336- 6342. First study to report the efficacy of an osteoporosis dose of ibadronate in the treatment of aromatase inhibitor induced bone loss.
    • (2008) Clin Cancer Res , vol.14 , pp. 6336-6342
    • Lester, J.E.1    Dodwell, D.2    Purohit, O.P.3
  • 34
    • 33947524592 scopus 로고    scopus 로고
    • Zoledronic acid inhibits adjuvant letrozole-induced bone loss in postmenopausal women with early breast cancer
    • Brufsky A, Harker WG, Beck JT, et al. Zoledronic acid inhibits adjuvant letrozole-induced bone loss in postmenopausal women with early breast cancer. J Clin Oncol 2007; 25:829-836.
    • (2007) J Clin Oncol , vol.25 , pp. 829-836
    • Brufsky, A.1    Harker, W.G.2    Beck, J.T.3
  • 35
    • 39749155815 scopus 로고    scopus 로고
    • Effective inhibition of aromatase inhibitor-associated bone loss by zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole (ZO-FAST study results)
    • Bundred NJ, Campbell ID, Davidson N. Effective inhibition of aromatase inhibitor-associated bone loss by zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole (ZO-FAST study results). Cancer 2008; 112:1001-1010.
    • (2008) Cancer , vol.112 , pp. 1001-1010
    • Bundred, N.J.1    Campbell, I.D.2    Davidson, N.3
  • 36
    • 70349757135 scopus 로고    scopus 로고
    • The effect of zoledronic acid on aromatase inhibitor associated bone loss in postmenopausal women with early breast cancer receiving letrozole: 36 months follow-up of ZO-FAST
    • Presented at, 10-14 December, San Antonio, TX. Abstract 44
    • Eidtmann H, Bundred N, De Boer R, et al. The effect of zoledronic acid on aromatase inhibitor associated bone loss in postmenopausal women with early breast cancer receiving letrozole: 36 months follow-up of ZO-FAST. Presented at 31st San Antonio Breast Cancer Symposium; 10-14 December 2008; San Antonio, TX. Abstract 44.
    • (2008) 31st San Antonio Breast Cancer Symposium
    • Eidtmann, H.1    Bundred, N.2    De Boer, R.3
  • 37
    • 74549194567 scopus 로고    scopus 로고
    • Zoledronic acid (ZA) prevents aromatase inhibitor (AI)-associated bone loss in postmenopausal women with early breast cancer: 36-month follow-up of the Z-FAST study [poster]
    • Presented at, 15-19 April, Berlin, Germany. Abstract 494
    • Brufsky A, Bosserman L, Caradonna R, et al. Zoledronic acid (ZA) prevents aromatase inhibitor (AI)-associated bone loss in postmenopausal women with early breast cancer: 36-month follow-up of the Z-FAST study [poster]. Presented at 6th European Breast Cancer Conference; 15-19 April 2008; Berlin, Germany. Abstract 494.
    • (2008) 6th European Breast Cancer Conference
    • Brufsky, A.1    Bosserman, L.2    Caradonna, R.3
  • 38
    • 0035960116 scopus 로고    scopus 로고
    • Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer
    • Smith MR, McGovern FJ, Zietman AL, et al. Pamidronate to prevent bone loss during androgen-deprivation therapy for prostate cancer. N Engl J Med 2001; 345:948-955.
    • (2001) N Engl J Med , vol.345 , pp. 948-955
    • Smith, M.R.1    McGovern, F.J.2    Zietman, A.L.3
  • 39
    • 33750607172 scopus 로고    scopus 로고
    • Effects of alendronate on bone mineral density in men with prostate cancer treated with androgen deprivation therapy
    • Bruder JM, Ma JZ, Wing N, et al. Effects of alendronate on bone mineral density in men with prostate cancer treated with androgen deprivation therapy. J Clin Densitom 2006; 9:431-437.
    • (2006) J Clin Densitom , vol.9 , pp. 431-437
    • Bruder, J.M.1    Ma, J.Z.2    Wing, N.3
  • 40
    • 33947732766 scopus 로고    scopus 로고
    • Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: A randomized trial
    • Greenspan SL, Nelson JB, Trump DL, Resnick NM. Effect of once-weekly oral alendronate on bone loss in men receiving androgen deprivation therapy for prostate cancer: a randomized trial. Ann Intern Med 2007; 146:416- 424.
    • (2007) Ann Intern Med , vol.146 , pp. 416-424
    • Greenspan, S.L.1    Nelson, J.B.2    Trump, D.L.3    Resnick, N.M.4
  • 41
    • 34249884844 scopus 로고    scopus 로고
    • The effect of zoledronic acid on bone mineral density in patients undergoing androgen deprivation therapy
    • Israeli RS, Rosenberg SJ, Saltzstein DR, et al. The effect of zoledronic acid on bone mineral density in patients undergoing androgen deprivation therapy. Clin Genitourin Cancer 2007; 5:271-277.
    • (2007) Clin Genitourin Cancer , vol.5 , pp. 271-277
    • Israeli, R.S.1    Rosenberg, S.J.2    Saltzstein, D.R.3
  • 42
    • 33746555619 scopus 로고    scopus 로고
    • Zoledronic acid initiated during the first year of androgen deprivation therapy increases bone mineral density in patients with prostate cancer
    • Ryan CW, Huo D, Demers LM, et al. Zoledronic acid initiated during the first year of androgen deprivation therapy increases bone mineral density in patients with prostate cancer. J Urol 2006; 176:972-978.
    • (2006) J Urol , vol.176 , pp. 972-978
    • Ryan, C.W.1    Huo, D.2    Demers, L.M.3
  • 43
    • 0038075478 scopus 로고    scopus 로고
    • Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer
    • Smith MR, Eastham J, Gleason DM, et al. Randomized controlled trial of zoledronic acid to prevent bone loss in men receiving androgen deprivation therapy for nonmetastatic prostate cancer. J Urol 2003; 169:2008- 2012.
    • (2003) J Urol , vol.169 , pp. 2008-2012
    • Smith, M.R.1    Eastham, J.2    Gleason, D.M.3
  • 44
    • 74549121433 scopus 로고    scopus 로고
    • Zoledronic acid as adjunct to androgen deprivation therapy reduces bone loss in men with prostate cancer [poster]
    • Presented at, 5-8 April, Paris, France. Abstract 139
    • Casey R, Love W, Mendoza C, et al. Zoledronic acid as adjunct to androgen deprivation therapy reduces bone loss in men with prostate cancer [poster]. Presented at 21st Annual EAU Congress; 5-8 April 2006; Paris, France. Abstract 139.
    • (2006) 21st Annual EAU Congress
    • Casey, R.1    Love, W.2    Mendoza, C.3
  • 45
    • 34047237418 scopus 로고    scopus 로고
    • Randomized controlled trial of annual zoledronic acid to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer
    • Michaelson MD, Kaufman DS, Lee H, et al. Randomized controlled trial of annual zoledronic acid to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer. J Clin Oncol 2007; 25:1038-1042.
    • (2007) J Clin Oncol , vol.25 , pp. 1038-1042
    • Michaelson, M.D.1    Kaufman, D.S.2    Lee, H.3
  • 46
    • 33744828376 scopus 로고    scopus 로고
    • Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]
    • Powles T, Paterson A, McCloskey E, et al. Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]. Breast Cancer Res 2006; 8:R13.
    • (2006) Breast Cancer Res , vol.8
    • Powles, T.1    Paterson, A.2    Mccloskey, E.3
  • 47
    • 56749165071 scopus 로고    scopus 로고
    • Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow: A long-term follow-up
    • Update of ground-breaking study of adjuvant bisphosphonates in early breast cancer
    • Diel IJ, Jaschke A, Solomayer EF, et al. Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow: a long-term follow-up. Ann Oncol 2008; 12:2007-2011. Update of ground-breaking study of adjuvant bisphosphonates in early breast cancer.
    • (2008) Ann Oncol , vol.12 , pp. 2007-2011
    • Diel, I.J.1    Jaschke, A.2    Solomayer, E.F.3
  • 48
    • 0035148170 scopus 로고    scopus 로고
    • Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial
    • Saarto T, Blomqvist C, Virkkunen P, Elomaa I. Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5-year results of a randomized controlled trial. J Clin Oncol 2001; 19:10-17.
    • (2001) J Clin Oncol , vol.19 , pp. 10-17
    • Saarto, T.1    Blomqvist, C.2    Virkkunen, P.3    Elomaa, I.4
  • 49
    • 34250326616 scopus 로고    scopus 로고
    • Meta-analysis of clodronate and breast cancer survival
    • Ha TC, Li H. Meta-analysis of clodronate and breast cancer survival. Br J Cancer 2007; 96:1796-1801.
    • (2007) Br J Cancer , vol.96 , pp. 1796-1801
    • Ha, T.C.1    Li, H.2
  • 50
    • 45149083364 scopus 로고    scopus 로고
    • Bisphosphonate treatment in primary breast cancer: Results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer
    • Kristensen B, Ejlertsen B, Mouridsen HT, et al. Bisphosphonate treatment in primary breast cancer: results from a randomised comparison of oral pamidronate versus no pamidronate in patients with primary breast cancer. Acta Oncol 2008; 47:740-746.
    • (2008) Acta Oncol , vol.47 , pp. 740-746
    • Kristensen, B.1    Ejlertsen, B.2    Mouridsen, H.T.3
  • 51
    • 25444477545 scopus 로고    scopus 로고
    • Compliance and persistence with bisphosphonate dosing regimens among women with postmenopausal osteoporosis
    • Cramer JA, Amonkar MM, Hebborn A, Altman R. Compliance and persistence with bisphosphonate dosing regimens among women with postmenopausal osteoporosis. Curr Med Res Opin 2005; 21:1453-1460.
    • (2005) Curr Med Res Opin , vol.21 , pp. 1453-1460
    • Cramer, J.A.1    Amonkar, M.M.2    Hebborn, A.3    Altman, R.4
  • 52
    • 50249133642 scopus 로고    scopus 로고
    • Benefit of adherence with bisphosphonates depends on age and fracture type: Results froman analysis of 101, 038 new bisphosphonate users
    • Curtis JR, Westfall AO, Cheng H, et al. Benefit of adherence with bisphosphonates depends on age and fracture type: results froman analysis of 101, 038 new bisphosphonate users. J Bone Miner Res 2008; 23:1435-1441.
    • (2008) J Bone Miner Res , vol.23 , pp. 1435-1441
    • Curtis, J.R.1    Westfall, A.O.2    Cheng, H.3
  • 53
    • 60549097419 scopus 로고    scopus 로고
    • Endocrine therapy plus zoledronic acid in premenopausal breast cancer
    • Ground-breaking study indicating adjuvant role for zoledronic acid in endocrinesensitive premenopausal breast cancer
    • Gnant M, Mlineritsch B, Schippinger W, et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. New Engl J Med 2009; 360:679-691. Ground-breaking study indicating adjuvant role for zoledronic acid in endocrinesensitive premenopausal breast cancer.
    • (2009) New Engl J Med , vol.360 , pp. 679-691
    • Gnant, M.1    Mlineritsch, B.2    Schippinger, W.3
  • 54
    • 43749115751 scopus 로고    scopus 로고
    • The bone marrow niche: Habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites
    • Shiozawa Y, Havens AM, Pienta KJ, et al. The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites. Leukemia 2008; 22:941-950.
    • (2008) Leukemia , vol.22 , pp. 941-950
    • Shiozawa, Y.1    Havens, A.M.2    Pienta, K.J.3
  • 55
    • 50549121134 scopus 로고
    • Secondary growth in cancer of breast
    • Paget S. Secondary growth in cancer of breast. Lancet 1889; 571-572.
    • (1889) Lancet , pp. 571-572
    • Paget, S.1


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