Exogenous expression of caspase-14 induces tumor suppression in human salivary cancer cells by inhibiting tumor vascularization

Anticancer Research

Volumn 29, Issue 10, 2009, Pages 3811-3818

  Wu, Mengjie ^a   Kodani, Isamu ^b   Dickinson, Douglas ^c   Huff, Frank ^c   Ogbureke, Kalu U E ^c   Qin, Haiyan ^c   Arun, Senthil ^c   Dulebohn, Rachel ^c   Al Shabrawey, Mohamed ^c   Tawhk, Amany ^c   Prater, Susan ^c   Lewis, Jill ^c   Wataha, John ^d   Messer, Regina ^c   Hsu, Stephen ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b TOTTORI UNIVERSITY HOSPITAL   (Japan)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Caspase 14; Gene therapy; Salivary gland cancer; Vascularization

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BROXURIDINE; CASPASE 14; CASPASE 14 PCMV6 XL4 PLASMID; COMPLEMENTARY DNA; PLASMID DNA; PLASMID VECTOR; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC GENE THERAPY; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; CARCINOGENICITY; CELL COUNT; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; EXPRESSION VECTOR; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; MICROSCOPY; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SALIVARY GLAND CARCINOMA; TRANSIENT TRANSFECTION; TUMOR GROWTH; TUMOR VASCULARIZATION; TUMOR VOLUME;

ADENOCARCINOMA; ANIMALS; CASPASE 14; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DNA, NEOPLASM; FEMALE; GENE THERAPY; GENETIC VECTORS; HUMANS; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; PLASMIDS; SALIVARY GLAND NEOPLASMS; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 71949125506     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Hsu S, Singh B and Schuster GS: Inducing apoptosis in oral cancer cells. Oral Oncology 40: 461-473, 2004.
2. Speight PM and Barrett AW: Salivary gland tumours. Oral Dis 8: 229-240, 2002.
3. Brandwein MS, Ferlito A, Bradley PJ, Hille JJ and Rinaldo A: Diagnosis and classification of salivary neoplasms: pathologic challenges and relevance to clinical outcomes. Acta Otolaryngol 122: 758-764, 2002. (Pubitemid 35398889)
4. Mendenhall WM, Riggs CE Jr and Cassisi NJ: Treatment of head and neck cancers. In: Cancer: Principles and Practice of Oncology. 7th ed. De Vita VT Jr, Hellman S and Rosenberg SA (eds.). Philadelphia, Pa: Lippincott Williams & Wilkins, pp. 662-732, 2005.
5. O'Malley BW Jr and Li D: Combination gene therapy for salivary gland cancer. Ann N Y Acad Sci 842: 163-170, 1998. (Pubitemid 28227019)
6. Zhang Y, Wang H, Toratani S, Sato JD, Kan M, McKeehan WL and Okamoto T: Growth inhibition by keratinocyte growth factor receptor of human salivary adenocarcinoma cells through induction of differentiation and apoptosis. Proc Natl Acad Sci USA 98: 11336-11340, 2001. (Pubitemid 32928729)
7. Lippens S, Kockx M, Knaapen M, Mortier L, Polakowska R, Verheyen A, Garmyn M, Zwijsen A, Formstecher P, Huylebroeck D, Vandenabeele P and Declercq W: Epidermal differentiation does not involve the pro apoptotic executioner caspases, but is associated with caspase-14 induction and processing. Cell Death Differ 7: 1218-1224, 2000. (Pubitemid 32042229)
8. Madison KC: Barrier function of the skin: "la raison d'etre" of the epidermis. J Invest Dermatol 121: 231-241, 2003.
9. Nickoloff BJ, Qin JZ, Chaturvedi V, Bacon P, Panella J and Denning MF: Life and death signaling pathways contributing to skin cancer. J Investig Dermatol Symp Proc 7: 27-35, 2002. (Pubitemid 36151091)
10. Denecker G, Hoste E, Gilbert B, Hochepied T, Ovaere P, Lippens S, Van den Broecke C, Van Damme P, D'Herde K, Hachem JP, Borgonie G, Presland RB, Schoonjans L, Libert C, Vandekerckhove J, Gevaert K, Vandenabeele P and Declercq W: Caspase-14 protects against epidermal UVB photodamage and water loss. Nat Cell Biol 9: 666-674, 2007. (Pubitemid 47214729)
11. Hsu S, Dickinson D, Borke J, Qin H, Winger J, Henna P, Walsh D, Bollag WB, Wood J and Schuster G: Green tea polyphenols reduced the psoriasiform lesions and regulate caspase-14 by the mitogen-activated protein kinase pathways. Exp Dermatol 16: 678-684, 2007.
12. Hsu S, Yamamoto T, Borke J, Walsh DS, Singh B, Rao S, Takaaki K, Lapp C, Lapp D, Foster E, Bollag WB, Lewis J, Wataha J, Osaki T and Schuster G: Green tea polyphenol-induced epithelial cell terminal differentiation is associated with coordinated expression of p57/KIP2 and caspase-14. J Pharmacol Exp Ther 312: 884-890, 2005. (Pubitemid 40293745)
13. Hsu S, Qin H, Dickinson D, Xie D, Bollag WB, Stöppler H, Pearl H, Vu A, Watkins M, Koehler M and Schuster G: Expression of caspase-14 reduces tumorigenicity of skin cancer cells. In Vivo 21: 279-283, 2007. (Pubitemid 46534281)
14. Ota M, Kyakumoto S and Sato N: Proliferation and differentiation of human salivary gland adenocarcinoma cell line HSG. Hum Cell 9: 79-88, 1996.
15. Hsu S, Dickinson D, Qin H, Borke J, Ogbureke K, Walsh D, Bollag WB, Stoppler H, Sharawy M and Schuster G: Green tea polyphenols reduce autoimmune symptoms in a murine model for human Sjogren's syndrome and protect human salivary gland cells from TNF-α-induced cytotoxicity. Autoimmunity 40: 138-147, 2007. (Pubitemid 46431570)
16. Yamamoto T, Staples J, Wataha J, Lewis J, Lockwood P, Schoenlein P, Rao S, Osaki T, Dickinson D, Kamatani T, Schuster G and Hsu S: Protective effects of EGCG on salivary gland cells treated with γ-radiation or cis-platinum(II)diammine dichloride. 2004. Anticancer Res 24: 3065-3073, 2004. (Pubitemid 39407187)
17. Gillespie K, Kodani I, Dickinson DP, Ogbureke KUE, Camba AM, Wu M, Looney S, Chu TC, Qin H, Bisch F, Sharawy M, Schuster G and Hsu SD: Effects of oral consumption of the green tea polyphenol EGCG in a murine model for human Sjogren's syndrome, an autoimmune disease. Life Sciences 83: 581-588, 2008.
18. Eckhart L, Ban J, Fischer H and Tschachler E: Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation. Biochem Biophys Res Commun 277: 655-659, 2000. (Pubitemid 30819735)
19. Rendl M, Ban J, Mrass P, Mayer C, Lengauer B, Eckhart L, Declerq W and Tschachler E: Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner. J Invest Dermatol 119: 1150-1155, 2002. (Pubitemid 35430492)
20. Yoo NJ, Soung YH, Lee SH, Jeong EG and Lee SH: Mutational analysis of caspase-14 gene in common carcinomas. Pathology 39: 330-333, 2007. (Pubitemid 46897596)
21. Krajewska M, Kim H, Shin E, Kennedy S, Duffy MJ, Wong YF, Marr D, Mikolajczyk J, Shabaik A, Meinhold-Heerlein I, Huang X, Banares S, Hedayat H, Reed JC and Krajewski S: Tumor-associated alterations in caspase-14 expression in epithelial malignancies. Clin Cancer Res 11: 5462-5471, 2005. (Pubitemid 41060822)