Study of separation and extraction conditions for five neuroleptic drugs by an LLE-HPLC-DAD method in human plasma

Journal of Liquid Chromatography and Related Technologies

Volumn 32, Issue 20, 2009, Pages 3025-3037

  Madej, K ^a   Biedron A ^a   Garbacik, A ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Antipsychotic drugs; Atypical neuroleptics; High performance liquid chromatography; Human plasma; Liquid liquid extraction; Phenothiazine neuroleptics

Indexed keywords

ACTIVE METABOLITES; ANTIPSYCHOTIC DRUG; ANTIPSYCHOTIC DRUGS; BACK EXTRACTION; CLOZAPINE; EXTRACTION SYSTEMS; GRADIENT FLOW; HPLC-DAD; HUMAN PLASMAS; LIQUID-LIQUID EXTRACTION; MOBILE PHASE; ORTHOPHOSPHORIC ACIDS; REVERSE PHASE CHROMATOGRAPHY; SAMPLE PH; SEPARATION AND EXTRACTION;

ACETONITRILE; ACIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DRUG PRODUCTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; INSECTICIDES; PHOSPHORIC ACID; PLASMA (HUMAN); PLASMAS; SOLVENT EXTRACTION;

LIQUIDS;

2 PROPANOL; ACETIC ACID ETHYL ESTER; ACETONITRILE; CLOZAPINE; HEXANE; NEUROLEPTIC AGENT; NORCLOZAPINE; OLANZAPINE; PERAZINE; PHOSPHORIC ACID; QUETIAPINE;

ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIODE; DRUG ANALYSIS; DRUG ISOLATION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID LIQUID EXTRACTION; PARTICLE SIZE; PH; REVERSED PHASE LIQUID CHROMATOGRAPHY; SPECTROPHOTOMETRY; ULTRAVIOLET SPECTROSCOPY;

EID: 71949116301     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070903320582     Document Type: Article

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