Evaluation of the tocolytic effect of morphine in a mouse model of lipopolysaccharide-induced preterm delivery: The role of nitric oxide

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 147, Issue 2, 2009, Pages 166-172

  Javadi Paydar, Mehrak ^a,b   Lesani, Ali ^b,e   Vakilipour, Ramin ^b   Ghazi, Payam ^b   Tavangar, Seyed Mohammad ^c   Hantoushzadeh, Sedigheh ^d   Norouzi, Abbas ^a,d   Dehpour, Ahmad Reza ^e  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Lipopolysaccharide induced preterm delivery; Mice; Morphine; Naltrexone; Nitric oxide

Indexed keywords

LIPOPOLYSACCHARIDE; MORPHINE SULFATE; N(G) NITROARGININE METHYL ESTER; NALTREXONE; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; FEMALE; GESTATION PERIOD; HISTOPATHOLOGY; MALE; NONHUMAN; PLACENTA; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL;

EID: 71849118959     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejogrb.2009.08.014     Document Type: Article

References (31)

1. Holmgren C., Esplin M.S., Hamblin S., Molenda M., Simonsen S., and Silver R. Evaluation of the use of anti-TNF-α in an LPS-induced murine model. J Reprod Immunol 78 (2008) 134-139
2. Kaga N., Katsuki Y., Kajikawa S., and Shibutani Y. Preventive effect of ritodrine hydrochloride and/or urinary trypsin inhibitor against lipopolysaccharide-induced preterm delivery in mice. Acta Obstet Gynecol Scand 76 (1997) 811-816
3. Romero R., and Mazor M. Infection and preterm labor. Clin Obstet Gynecol 31 3 (1988) 553-584
4. Xu D.X., Chen Y.H., Wang H., Zhao L., Wang J.P., and Wei W. Effect of N-acetylcysteine on lipopolysaccharide induced intra uterine fetal death and intra uterine growth retardation in mice. Toxicol Sci 88 (2005) 525-533
5. Xu D.X., Chen Y.H., Wang H., Zhao L., Wang J.P., and Wei W. Tumor necrosis factor alpha partially contributes to lipopolysaccharide induced intra uterine fetal growth restriction and skeletal development retardation in mice. Toxicol Lett 163 (2006) 20-29
6. Kajikawa S., Kaga N., Futamura Y., Kakinuma C., and Shibutani Y. Lipotheichoic acid induces preterm delivery in mice. J Pharmacol Toxical Methods 39 (1998) 147-154
7. Xu D.X., Wang H., Zhao L., Ning H., Zhang C., and Chen Y.H. Effects of low dose lipopolysccharid (LPS) pretreatment on LPS-induced intra-uterine fetal death and preterm labor. Toxicology 234 (2007) 167-175
8. Fidel P.L., Romero R., Wolf N., et al. Systemic and local cytokine profiles in endotoxin-induced preterm parturition in mice. Am J Obstet Gynecol 170 (1994) 1467-1475
9. Gravett M.G., Witkin S.S., Haluska G.J., Edwards J.L., Cook M.J., and Novy M.J. An experimental model for intraamniotic infection and preterm labor in rhesus monkey. Am J Obstet Gynecol 171 (1994) 1660-1667
10. Zhu Y., and Paintar J.E. Expression of opioid receptor and ligands in pregnant mouse uterus and placenta. Biol Reprod 59 (1998) 925-932
11. Moncada S.R., Palmer M.G., and Higgs E.A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 43 (1995) 109-142
12. Bricker L., and Lavender T. Parenteral opioida for labor pain relief: a systemic review. Am J Obstet Gynecol 186 (2002) S94-109
13. Yallampalli C., Garfield R.E., and Byan-Smith M. Nitric oxide inhibits uterine contractility during pregnancy but not during delivery. Endocrinol 133 (1993) 1899-1902
14. Helmbrecht G.D., Farhat M.Y., Lochbaum L., et al. l-Arginine reverse the adverse pregnancy changes induced by nitric oxide synthase inhibition in the rat. Am J Obstet Gynecol 175 (1996) 800-805
15. Yallampalli C., Burnmscrn I., Chwalisz K., Garfield R.E., and Dong Y.L. Preterm birth in rats produced by the synergistic action of a nitric oxide inhibitor (NG-nitro-targinine methyl ester) and an antiprogestin (onapristone). Am J Obstet Gynecol 175 (1996) 207-212
16. Tiboni G.M., and Glampietro F. Inhibition of nitric oxide synthesis causes preterm delivery in the mouse. Hum Reprod 15 (2000) 1838-1842
17. Welters I.D., Menzebach A., Goumon Y., et al. Morphine inhibits NF-KB nuclear binding in human nutrophils and monocytes by a nitric oxide dependent mechanism. Anesthesiology 92 (2000) 1677-1684
18. Magazine H.I., Liu Y., Bilfinger T.V., Fricchione G.L., and Stefano G.B. Morphine-induced conformational changes in human monocytes, granulocytes and endothelial cells and in invertebrate immunocytes and microglia are mediated by nitric oxide. J Immunol 156 (1996) 4845-4850
19. Kaga N., Katsuki Y., Obata M., and Shibutani Y. Repeated administration of low-dose lipopolysaccharide induces preterm delivery in mice: a model for human preterm parturition and for assessment of the therapeutic ability of drugs against preterm delivery. Am J Ostet Gynecol 174 (1996) 754-759
20. de Pace V., Chiossi G., and Facchinetti F. Clinical use of nitric oxide donors and l-arginine in obstetrics. J Matern Fetal Neonatal Med 20 8 (2007) 569-579 [Review]
21. Marinoni E., Di Iorio R., Villaccio B., Alberini A., Rota F., and Cosmi E.V. Amniotic fluid nitric oxide metabolite levels and nitric oxide synthase localization in feto-placental tissues are modified in association with human labor. Eur J Obstet Gynecol Reprod Biol 89 (2000) 47-54
22. Kelly N.M., and Cross A.S. Interlukin-6 is a better marker of lethality than tumor necrosis factor in endotoxin treated mice. FEMS Microbiol Immunol 89 (1992) 317-322
23. Ogando D.G., Paz D., Cella M., and Franchi A.M. The fundamental role of increased production of nitric oxide in lipopolysaccharide-induced embryonic resorption in mice. Reproduction 125 (2003) 95-110
24. Athanassakis I., Aifantis I., Ranella A., Giouremou K., and Vassiliadis S. Inhibition of nitric oxide production rescues LPS-induced fetal abortion in mice. Nitric Oxide 3 (1999) 216-224
25. Weber N.C., Kandler J., Schlack W., Grueber Y., Frabdorf J., and Preckel B. Intermitted pharmacologic pretreatment by xenon, isoflurane, nitrous oxide and the opioid morphine prevents tumor necrosis factor alpha induced adhesion molecule expression in human umbilical vein endothelial cells. Anesthesiology 108 (2008) 199-207
26. Santolaya-Forgas J., Romero R., and Mehendale R. The effect of continuous morphine administration on maternal plasma oxytocin concentration and uterine contractions after open fetal surgery. J Maternal-Fetal Neonatal Med 19 4 (2006) 231-238
27. Fimiani C., Mattocks D., Cavani F., et al. Morphine and anandamide stimulate intracellular calcium transient in human arterial endothelial cells: coupling to nitric oxide release. Cell Signal 11 (1999) 189-193
28. Tseng L., Mazella J., Goligorsky M.S., Rialas C.M., and Stefano G.B. Dopamine and morphine stimulate nitric oxide release in human endometrial glandular epithelial cells. J Soc Gynecol Investig 7 6 (2000) 343-347
29. McKay D.G., and Wong T.C. The effect of bacterial endotoxin on the placenta of the rat. Am J Pathol 42 (1963) 357-377
30. Russell J.A., Gosden R.G., Humphreys E.M., et al. Interruption of parturition in rats by morphine: a result of inhibition of oxytocin secretion. J Endocrinol 121 3 (1989) 521-536
31. Russell J.A., Leng G., Coombes J.E., et al. Pethidine (meperidine) inhibition of oxytocin secretion and action in parturient rats. Am J Physiol 261 (1991) R358-R368