From selection to caged aptamers: Identification of light-dependent ssDNA aptamers targeting cytohesin

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 23, 2009, Pages 6561-6564

  Mayer, Günter ^a,b   Lohberger, Andrea ^b   Butzen, Sabine ^b   Pofahl, Monika ^a,b   Blind, Michael ^c   Heckel, Alexander ^d  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF BONN   (Germany)

^c NascaCell Technologies AG   (Germany)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

Aptamers; Caged compounds; Nucleic acids

Indexed keywords

APTAMER; CYTOHESIN 1; DNA;

ARTICLE; DNA LIBRARY; DNA SEQUENCE; LIGHT; PROTEIN SECONDARY STRUCTURE; SYNTHESIS;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BINDING SITES; DNA, SINGLE-STRANDED; GUANINE NUCLEOTIDE EXCHANGE FACTORS; LIGHT; MOLECULAR SEQUENCE DATA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 71849100889     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.032     Document Type: Article

References (22)

1. Goeldner M., and Givens R. Dynamic Studies in Biology (2005), Wiley-VCH, Weinheim
2. Mayer G., and Heckel A. Angew. Chem., Int. Ed. 45 (2006) 4900
3. Young D.D., and Deiters A. Org. Biomol. Chem. 5 (2007) 999
4. Tang X., Maegawa S., Weinberg E.S., and Dmochowski I.J. J. Am. Chem. Soc. 129 (2007) 11000
5. Heckel A., Buff M.C., Raddatz M.S., Müller J., Pötzsch B., and Mayer G. Angew. Chem., Int. Ed. 45 (2006) 6748
6. Heckel A., and Mayer G. J. Am. Chem. Soc. 127 (2005) 822
7. Mayer G., Kröck L., Mikat V., Engeser M., and Heckel A. ChemBioChem 6 (2005) 1966
8. Mayer G., Müller J., Mack T., Freitag D.F., Hover T., Pötzsch B., and Heckel A. ChemBioChem 10 (2009) 654
9. Mikat V., and Heckel A. RNA 13 (2007) 2341
10. Mayer G. Angew. Chem. Int. Ed. 48 (2009) 2672
11. Wilson D.S., and Szostak J.W. Annu. Rev. Biochem. 68 (1999) 611
12. Bock L.C., Griffin L.C., Latham J.A., Vermaas E.H., and Toole J.J. Nature 355 (1992) 564
13. Padmanabhan K., Padmanabhan K.P., Ferrara J.D., Sadler J.E., and Tulinsky A. J. Biol. Chem. 268 (1993) 17651
14. Kolanus W. Immunol. Rev. 218 (2007) 102
15. Kolanus W., Nagel W., Schiller B., Zeitlmann L., Godar S., Stockinger H., and Seed B. Cell 86 (1996) 233
16. Mayer G., Blind M., Nagel W., Bohm T., Knorr T., Jackson C.L., Kolanus W., and Famulok M. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 4961
17. Theis M.G., Knorre A., Kellersch B., Moelleken J., Wieland F., Kolanus W., and Famulok M. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 11221
18. Cox J.C., and Ellington A.D. Bioorg. Med. Chem. 9 (2001) 2525
19. Mayer G., Wulffen B., Huber C., Brockmann J., Flicke B., Neumann L., Hafenbradl D., Klebl B.M., Lohse M.J., Krasel C., and Blind M. Rna 14 (2008) 524
20. Hafner M., Schmitz A., Grune I., Srivatsan S.G., Paul B., Kolanus W., Quast T., Kremmer E., Bauer I., and Famulok M. Nature 444 (2006) 941
21. Walter A.E., Turner D.H., Kim J., Lyttle M.H., Muller P., Mathews D.H., and Zuker M. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 9218
22. Zuker M., and Stiegler P. Nucleic Acids Res. 9 (1981) 133