Smart controlled preparation of multilayered hydrogel for releasing bioactive molecules

Current Applied Physics

Volumn 9, Issue 4 SUPPL., 2009, Pages

  Choi, Jiyeon ^a   Konno, Tomohiro ^a   Takai, Madoka ^a   Ishihara, Kazuhiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Controlled drug release; Layer by layer method; Multilayered hydrogel; Phospholipid polymer; VEGF

Indexed keywords

BIOACTIVE MOLECULES; CARBOXYL GROUPS; CONTROLLED DRUG RELEASE; COVALENT BONDING; DRUG DELIVERY SYSTEM; ELECTROSTATIC INTERACTIONS; GROWTH FACTOR; LAYER-BY-LAYER METHOD; LAYER-BY-LAYER METHODS; MULTI-LAYERED; N ,N-DIMETHYLAMINOETHYL METHACRYLATE; PH SENSITIVE; PHOSPHOLIPID POLYMERS; POLYMER MULTILAYERS; POSITIVELY CHARGED; SUGAR BINDING; SURFACE COMPOSITIONS; VEGF RELEASE; WATER-SOLUBLE PHOSPHOLIPID POLYMERS;

ALGINATE; ANGLE MEASUREMENT; CONTACT ANGLE; DRUG DELIVERY; FLUORINE CONTAINING POLYMERS; GLUCOSE; PHOSPHOLIPIDS; POLYMERS; SUGAR (SUCROSE); SURFACE PLASMON RESONANCE; TITANIUM; TITANIUM ALLOYS;

HYDROGELS;

EID: 71849095536     PISSN: 15671739     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cap.2009.06.054     Document Type: Article

References (13)

1. Patel Z.S., and Mikos A. Angiogenesis with biomaterial-based drug- and cell-delivery systems. J. Biomater. Sci. Polym. Ed. 15 (2004) 701-726
2. Gu F., Amsden B., and Neufeld R. Sustained delivery of vascular endothelial growth factor with alginate beads. J. Controlled Release 96 (2004) 463-472
3. Matsusaki M., Sakaguchi H., Serizawa T., and Akashi M. Controlled release of vascular endothelial growth factor from alginate hydrogels nano-coated with polyelectrolyte multilayer films. J. Biomater. Sci. Polym. Ed. 18 (2007) 775-783
4. Augst A.D., Kong H.J., and Mooney D.J. Alginate hydrogels as biomaterials. Macromol. Biosci. 6 (2006) 623-633
5. Huang M., Vitharana S.N., Peek L.J., Coop T., and Berkland C. Polyelectrolyte complexes stabilize and controllably release vascular endothelial growth factor. Biomacromolecules 8 (2007) 1607-1614
6. Ishihara K., Nomura H., Mihara T., Kurita K., Iwasaki Y., and Nakabayashi N. Why do phospholipid polymers reduce protein adsorption?. J. Biomed. Mater. Res. 39 (1998) 323-330
7. Sawada S., Iwasaki Y., Nakabayashi N., and Ishihara K. Stress response of adherent cells on a polymer blend surface composed of a segmented polyurethane and MPC copolymers. J. Biomed. Mater. Res. 79A (2006) 476-484
8. Konno T., and Ishihara K. Temporal and spatially controllable cell encapsulation using a water-soluble phospholipid polymer with phenylboronic acid moiety. Biomaterials 28 (2007) 1770-1777
9. Choi J., Konno T., Matsuno R., Takai M., and Ishihara K. Surface immobilization of biocompatible phospholipid polymer multilayered hydrogel on titanium alloy. Colloid Surf. B 67 (2008) 216-223
10. Ishihara K., Ueda T., and Nakabayashi N. Preparation of phospholipid polymers and their properties as polymer hydrogel membranes. Polym. J. 22 (1990) 355-360
11. van den Beucken J.J.J.P., Walboomers X.F., Boerman O.C., Vos M.R.J., Sommerdijk N.A.J.M., Hayakawa T., Fukushima T., Okahata Y., Nolte R.J.M., and Jansen J.A. Functionalization of multilayered DNA-coatings with bone morphogenetic protein 2. J. Controlled Release 113 (2006) 63-72
12. Yamauchi F., Koyamatsu Y., Kato K., and Iwata H. Layer-by-layer assembly of cationic lipid and plasmid DNA onto gold surface for stent-assisted gene transfer. Iwata, Biomaterials 27 (2006) 3497-3504
13. 2+-alginate gel dissolution on release of dextran with different molecular weights. J. Controlled Release 58 (1999) 21-28