A chromatographic procedure for semi-quantitative evaluation of caseinphosphopeptides in cheese

Dairy Science and Technology

Volumn 89, Issue 6, 2009, Pages 519-529

  Dupas, Coralie ^a   Adt, Isabelle ^a   Cottaz, Amandine ^a   Boutrou, Rachel ^b   Molle, Daniel ^b   Jardin, Julien ^b   Jouvet, Thierry ^c   Degraeve, Pascal ^a  

^a UNIVERSITÉ LYON 1   (France)

^b AGROCAMPUS OUEST   (France)

^c Technopole Alimentec   (France)

Author keywords

Caseinphosphopeptide; Cheese; Liquid chromatography; Mass spectrometry

Indexed keywords

EID: 71749090234     PISSN: 19585586     EISSN: 19585594     Source Type: Journal    
DOI: 10.1051/dst/2009027     Document Type: Article

References (23)

1. Adamson N.J., Reynolds E.C., Characterization ofmultiply phosphorylated peptides selectively precipitated from a pancreatic casein digest, J. Dairy Sci. 78 (1995) 2653-2659.
2. Addeo F., Chianese L., Sacchi R., Spagna Musso S., Ferranti P., Malorni A., Characterization of the oligopeptides of Parmigiano- Reggiano cheese soluble in 120 g trichloroacetic acid/L, J. Dairy Res. 61 (1994) 365-374.
3. Aimutis W.R., Bioactive properties of milk proteins with particular focus on anticariogenesis, J. Nutr. 134 (2004) 989-995.
4. Chabance B., Marteau P., Rambaud J.C., Migliore-Samour D., Boynard M., Perrotin P., Guillet R., Jolles P., Fiat A.M., Casein peptide release and passage to the blood in humans during digestion of milk or yogurt, Biochimie 80 (1998) 155-165.
5. Ferranti P., Barone F., Chianese L., Addeo F., Scaloni A., Pellegrino L., Resmini P., Phosphopeptides from Grana Padano cheese: Nature, origin and changes during ripening, J. Dairy Res. 64 (1997) 601-615.
6. Ferraretto A., Gravaghi C., Fiorilli A., Tettamanti G., Casein-derived bioactive phosphopeptides: role of phosphorylation and primary structure in promoting calcium uptake by HT-29 tumor cells, FEBS Lett. 551 (2003) 92-98.
7. FitzGerald R.J., Potential uses of caseinophosphopeptides, Int. Dairy J. 8 (1998) 451-457.
8. GagnaireV., Mollé D., Herrouin M., Léonil J., Peptides identified during cheese ripening: origin and proteolytic systems involved, J. Agric. Food Chem. 49 (2001) 4402-4413.
9. García M.C., Hogenboom A.C., Zappey H., Irth H., Effect of the mobile phase composition on the separation and detection of intact proteins by reversed-phase liquid chromatography- electrospray mass spectrometry, J. Chromatogr. 957 (2002) 187-199.
10. Hartmann R., Meisel H., Food-derived peptides with biological activity: from research to food applications, Curr. Opin. Biotechnol. 18 (2007) 163-169.
11. Hynek R., Kozak A., Drab V., Sajdok J., Kas J., Characterization of casein phosphopeptides in cheese extracts using a combination of immobilized metal chelate affinity and reversed-phase high-performance liquid chromatography, Adv. Food Sci. 21 (1999) 192-196.
12. Kawahara T., Aruga K., Otani H., Characterization of casein phosphopeptides from fermented milk products, J. Nutr. Sci. Vitaminol. 51 (2005) 377-381.
13. Kuchroo C.N., Fox P., Soluble nitrogen in cheddar cheese: Comparison of extraction procedures, Milchwissenschaft 37 (1982) 331-335.
14. Lund M., Ardö Y., Purification and identification of water-soluble phosphopeptides from cheese using Fe(III) affinity chromatography and mass spectrometry, J. Agric. Food Chem. 52 (2004) 6616-6622.
15. Meisel H., Overview on milk proteinderivated peptides, Int. Dairy J. 8 (1998) 363-373.
16. Miquel E., Gomez J.A., Alegra A., Barber R., Farr R., Recio I., Identification of casein phosphopeptides released after simulated digestion of milk-based infant formulas, J. Agric. Food Chem. 53 (2005) 3426-3433.
17. Morgan M.V., Adams G.G., Bailey D.L., Tsao C.E., Fischman S.L., Reynolds E.C., The anticariogenic effect of sugar-free gum containing CPP-ACP nanocomplexes on approximal caries determined using digital bitewing radiography, Caries Res. 42 (2008) 171-184.
18. Peres J.M., Bouhallab S., Bureau F., Neuville D., Maubois J.L., Devroede G., Arhan P., Bougle D., Mechanisms of absorption of caseinophosphopeptide bound iron, J. Nutr. Biochem. 10 (1999) 215-222.
19. Reynolds E.C., Riley P.F., Adamson N.J., A selective precipitation purification procedure for multiple phosphoseryl-containing peptides and methods for their identification, Anal. Biochem. 217 (1994) 277-284.
20. Roudot-Algaron F., Le Bars D., Kerhoas L., Einhorn J., Gripon J.C., Phosphopeptides from Comté cheese: Nature and origin, J. Food Sci. 59 (1994) 544-547.
21. Sforza S., Ferroni L., Galaverna G., Dossena A., Marchelli R., Extraction, semi-quantification, and fast on-line identification of oligopeptides in Grana Padano cheese by HPLC-MS, J. Agric. Food Chem. 51 (2003) 2130-2135.
22. Shakeel-Ur-Rehman, Farkye N., Yim B., A preliminary study on the role of alkaline phosphatase in cheese ripening, Int. Dairy J. 16 (2006) 697-700.
23. Tsuchita H., Goto T., Shimizu T., Yonehara Y., Kuwata T., Dietary casein phosphopeptides prevent bone loss in aged ovariectomized rats, J. Nutr. 126 (1996) 86-93.