Design, synthesis, and preliminary studies of the activity of novel derivatives of N-cinnamoyl-l-aspartic acid as inhibitors of aminopeptidase N/CD13

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 20, 2009, Pages 7398-7404

  Liu, Yingzi ^a,b   Shang, Luqing ^a   Fang, Hao ^a   Zhu, Huawei ^a   Mu, Jiajia ^a   Wang, Qiang ^a   Wang, Xuejian ^a   Yuan, Yumei ^a   Xu, Wenfang ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG POLICE COLLEGE   (China)

Author keywords

Aminopeptidase N inhibitors; N Cinnamoyl l aspartic acid derivatives; Synthesis

Indexed keywords

ANTINEOPLASTIC AGENT; ASPARTIC ACID DERIVATIVE; ENZYME INHIBITOR; MICROSOMAL AMINOPEPTIDASE; MICROSOMAL AMINOPEPTIDASE INHIBITOR; N CINNAMOYLASPARTIC ACID; N4 BUTYL 2 CINNAMAMIDO N1 HYDROXYSUCCINAMIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL;

ANTIGENS, CD13; ASPARTIC ACID; CINNAMATES; DRUG DESIGN; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEASE INHIBITORS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 71749086696     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.07.014     Document Type: Article

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