Quantification of Flow Using Ultrasound and Microbubbles: A Disruption Replenishment Model Based on Physical Principles

Ultrasound in Medicine and Biology

Volumn 35, Issue 12, 2009, Pages 2007-2020

  Hudson, John M ^a   Karshafian, Raffi ^a   Burns, Peter N ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Blood flow; Contrast agents; Microbubble; Microcirculation

Indexed keywords

ACOUSTIC CONDITIONS; AXIAL PLANES; BLOOD FLOW; CLINICAL TOOLS; CONTRAST AGENT; CONTRAST ENHANCED ULTRASOUND; CROSS SECTION; EXPONENTIAL MODELS; FLOW PHANTOM; FLOW SYSTEMS; IMAGING PLANE; LOW MECHANICAL INDEX; MATHEMATICAL FUNCTIONS; MEASUREMENT DEVICE; MICRO-BUBBLE; MICROBUBBLES; MODEL-BASED; MOTION ARTIFACT; PHYSICAL PRINCIPLES; TIME COURSE; TIME-INTENSITY CURVES; ULTRASOUND BEAMS; ULTRASOUND FIELDS; VASCULAR SYSTEM;

ACOUSTIC WAVES; BLOOD; FUNCTIONS; HYDRODYNAMICS; MECHANICAL PROPERTIES; MICROCIRCULATION; ULTRASONIC APPLICATIONS; ULTRASONICS; VELOCITY;

ULTRASONIC IMAGING;

CONTRAST MEDIUM; PERFLUTREN;

ARTICLE; BLOOD VOLUME; CONTRAST ENHANCEMENT; DEVICE; ECHOGRAPHY; HEMODYNAMICS; MATHEMATICAL ANALYSIS; MEASUREMENT; MICROBUBBLE; MICROCIRCULATION; MORPHOLOGY; NON INVASIVE MEASUREMENT; PHANTOM; PHYSICAL MODEL; PRIORITY JOURNAL; VELOCITY;

BLOOD FLOW VELOCITY; COMPUTER SIMULATION; CONTRAST MEDIA; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MICROBUBBLES; MODELS, CARDIOVASCULAR; RHEOLOGY; ULTRASONOGRAPHY;

EID: 71749084493     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2009.06.1102     Document Type: Article

References (27)

1. Arditi M., Frinking P.J., Zhou X., and Rognin N.G. A new formalism for the quantification of tissue perfusion by the destruction-replenishment method in contrast ultrasound imaging. IEEE Trans Ultrason Ferroelectr Freq Control 53 (2006) 1118-1129
2. Armstrong W.F., Mueller T.M., Kinney E.L., Tickner E.G., Dillon J.C., and Feigenbaum H. Assessment of myocardial perfusion abnormalities with contrast-enhanced two-dimensional echocardiography. Circulation 66 (1982) 166-173
3. Beaulieu N.C., and Xie Q. An optimal lognormal approximation to lognormal sum distributions. IEEE Trans Vehicular Tech 53 (2004) 479-489
4. Cobbold R. Foundations of Biomedical Ultrasound (2007), Oxford University Press, Toronto
5. Correas J.M., Claudon M., Tranquart F., and Helenon A.O. The kidney: Imaging with microbubble contrast agents. Ultrasound Q 22 (2006) 53-66
6. Crow E.L., and Shimizu K. Lognormal Distributions (1988), Marcel Dekker, Inc.,, New York
7. DeMaria A.N., Bommer W., Kwan O.L., Riggs K., Smith M., and Waters J. In vivo correlation of thermodilution cardiac output and videodensitometric indicator-dilution curves obtained from contrast two-dimensional echocardiograms. J Am Coll Cardiol 3 (1984) 999-1004
8. Feinstein S.B. The powerful microbubble: From bench to bedside, from intravascular indicator to therapeutic delivery system, and beyond. Am J Physiol Heart Circ Physiol 287 (2004) H450-H457
9. Feinstein S.B. Contrast ultrasound imaging of the carotid artery vasa vasorum and atherosclerotic plaque neovascularization. J Am Coll Cardiol 48 (2006) 236-243
10. Goertz D.E., de Jong N., and van der Steen A.F. Attenuation and size distribution measurements of Definity and manipulated Definity populations. Ultrasound Med Biol 33 (2007) 1376-1388
11. Halpern E.J., Rosenberg M., and Gomella L.G. Prostate cancer: Contrast-enhanced us for detection. Radiology 219 (2001) 219-225
12. Jayaweera A.R., Matthew T.L., Sklenar J., Spotnitz W.D., Watson D.D., and Kaul S. Method for the quantitation of myocardial perfusion during myocardial contrast two-dimensional echocardiography. J Am Soc Echocardiogr 3 (1990) 91-98
13. Karshafian R., Burns P.N., and Henkelman M.R. Transit time kinetics in ordered and disordered vascular trees. Phys Med Biol 48 (2003) 3225-3237
14. Kaul S. Myocardial contrast echocardiography: 15 years of research and development. Circulation 96 (1997) 3745-3760
15. Koster J., Schlosser T., Pohl C., Lentz C., Lohmaier S., Veltmann C., Kuntz-Hehner S., Omran H., Luderitz B., Becher H., and Tiemann K. Blood flow assessment by ultrasound-induced destruction of echocontrast agents using harmonic power Doppler imaging: Which parameters determine contrast replenishment curves?. Echocardiography 18 (2001) 1-8
16. Krix M., Kiessling F., Farhan N., Schmidt K., Hoffend J., and Delorme S. A multivessel model describing replenishment kinetics of ultrasound contrast agent for quantification of tissue perfusion. Ultrasound Med Biol 29 (2003) 1421-1430
17. Lucidarme O., Franchi-Abella S., Correas J.M., Bridal S.L., Kurtisovski E., and Berger G. Blood flow quantification with contrast-enhanced US: "Entrance in the section" phenomenon-phantom and rabbit study. Radiology 228 (2003) 473-479
18. Mischi M., Kalker T., and Korsten E. Videodensitometric methods for cardiac output measurements. EURASIP J Appl Signal Proc 5 (2003) 479-489
19. Mulvagh S.L., DeMaria A.N., Feinstein S.B., Burns P.N., Kaul S., Miller J.G., Monaghan M., Porter T.R., Shaw L.J., and Villanueva F.S. Contrast echocardiography: Current and future applications. J Am Soc Echocardiogr 13 (2000) 331-342
20. Potdevin T.C., Fowlkes J.B., Moskalik A.P., and Carson P.L. Analysis of refill curve shape in ultrasound contrast agent studies. Med Phys 31 (2004) 623-632
21. Qian H., and Bassingthwaighte J.B. A class of flow bifurcation models with lognormal distribution and fractal dispersion. J Theor Biol 205 (2000) 261-268
22. Skyba D.M., Jayaweera A.R., Goodman N.C., Ismail S., Camarano G., and Kaul S. Quantification of myocardial perfusion with myocardial contrast echocardiography during left atrial injection of contrast. Implications for venous injection. Circulation 90 (1994) 1513-1521
23. Veltmann C., Lohmaier S., Schlosser T., Shai S., Ehlgen A., Pohl C., Becher H., and Tiemann K. On the design of a capillary flow phantom for the evaluation of ultrasound contrast agents at very low flow velocities. Ultrasound Med Biol 28 (2002) 625-634
24. Wei K. Assessment of myocardial blood flow and volume using myocardial contrast echocardiography. Echocardiography 19 (2002) 409-416
25. Wei K., Jayaweera A.R., Firoozan S., Linka A., Skyba D.M., and Kaul S. Quantification of myocardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation 97 (1998) 473-483
26. Wilson S.R., Burns P.N., Muradali D., Wilson J.A., and Lai X. Harmonic hepatic US with microbubble contrast agent: Initial experience showing improved characterization of hemangioma, hepatocellular carcinoma, and metastasis. Radiology 215 (2000) 153-161
27. Wilson S.R., Jang H.J., Kim T.K., and Burns P.N. Diagnosis of focal liver masses on ultrasonography: Comparison of unenhanced and contrast-enhanced scans. J Ultrasound Med 26 (2007) 775-787 quiz 88-90