Vascular Prostheses with Covalently Bound Gentamicin and Amikacin Reveal Superior Antibacterial Properties than Silver-impregnated Ones - An In Vitro Study

European Journal of Vascular and Endovascular Surgery

Volumn 38, Issue 6, 2009, Pages 697-706

  Osinska Jaroszuk M ^a   Ginalska, G ^b   Belcarz, A ^b   Uryniak, A ^c  

^a MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^c Municipal Hospital   (Poland)

Author keywords

Aminoglycosides; Antibacterial activity; Antibiotics; InterGard Silver; Vascular prostheses

Indexed keywords

AMIKACIN; GENTAMICIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BIOFILM; BLOOD VESSEL PROSTHESIS; CONTROLLED STUDY; COVALENT BOND; CYTOTOXICITY; DRUG RELEASE; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PRIORITY JOURNAL; SILVER IMPREGNATION; SKIN FIBROBLAST;

AMIKACIN; ANTI-BACTERIAL AGENTS; BACTERIA; BIOFILMS; BLOOD VESSEL PROSTHESIS; CELL PROLIFERATION; CELLS, CULTURED; COATED MATERIALS, BIOCOMPATIBLE; COLONY COUNT, MICROBIAL; DRUG STABILITY; FIBROBLASTS; GENTAMICINS; HUMANS; PROSTHESIS DESIGN; PROSTHESIS-RELATED INFECTIONS; SILVER; SKIN;

EID: 71649116202     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2009.09.003     Document Type: Article

References (37)

1. Hernández-Richter T., Schardey H.M., Wittman F., Mayr S., Schmitt-Sody M., Blasenbreu S., et al. Rifampin and triclosan but not silver is effective in preventing bacterial infection of vascular Dacron graft material. Eur J Vasc Endovasc Surg 26 (2003) 550-557
2. Darouiche R.O. Treatment of infections associated with surgical implants. N Engl J Med 350 (2004) 1422-1429
3. Bandyk F.D., Novotney M.L., Back M.R., Johnson B.L., and Schmacht D.C. Expanded application of in situ replacement for prosthetic graft infection. J Vasc Surg 34 (2001) 411-420
4. Geesey G.G. Bacterial behaviour at surfaces. Curr Opin Microbiol 4 (2001) 296-300
5. Mah T.-F., and O'Toole G.A. Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol 9 (2001) 34-39
6. Chiesa R., Astore D., Frigerio S., Garriboli R., Piccolo G., Castellano R., et al. Vascular prosthetic graft infection: epidemiology, bacteriology, pathogenesis and treatment. Acta Chir Belg 102 (2002) 238-247
7. Gao H., Lund L., Prag J., Sandermann J., and Lindholt J.S. Laparoscopic diagnosis and treatment of aortic vascular prosthetic graft infections in a porcine model. Eur J Vasc Endovasc Surg 35 (2008) 41-45
8. Wipke-Tevis D.D. Vascular infections: medical and surgical therapies. J Cardiovasc Nurs 13 (1999) 70-81
9. Risberg B., Drott C., Dalman P., Holm J., Ivarsson H., Jivegård L., et al. Oral ciprofloxacin versus intravenous cefuroxime as prophylaxis against postoperative infections in vascular surgery: a randomised double-blind, prospective multicentre study. Eur J Vasc Endovasc Surg 10 (1995) 346-351
10. Homer-Vanniasinkam S. Surgical site and vascular infections: treatment and prophylaxis. Int J Infect Dis 11 (2007) S17-S22
11. Earnshaw J.J. Methicillin-resistant Staphylococcus aureus: vascular surgeons should fight back. Eur J Vasc Endovasc Surg 24 (2002) 283-286
12. Lovering A.M., and MacGowan A.P. A comparative study of the rifampicin binding and elution characteristics for collagen- and albumin-sealed vascular grafts. Eur J Vasc Endovasc Surg 17 (1999) 347-350
13. Javerliat I., Goëau-Brisonnière O., Sivadon-Tardy V., Coggia M., and Gaillard J.-L. Prevention of Staphylococcus aureus graft infection by a new gelatin-sealed vascular graft prebonded with antibiotics. J Vasc Surg 46 (2007) 1026-1031
14. 2 and Pal-Lys-Lys soaking alone and in combination with intraperitoneal vancomycin prevent vascular graft biofilm in a subcutaneous rat pouch model of staphylococcal infection. Peptides 28 (2007) 1299-1303
15. Feng Q.L., Wu J., Chen G.Q., Cui F.Z., Kim T.N., and Kim J.O. A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus. J Biomed Mater Res 52 (2000) 662-668
16. McDonnell G., and Russell D. Antiseptics and disinfectants: activity, action and resistance. Clin Microb Rev 12 (1999) 147-179
17. Nichol I.E., Rose J.D., Brown A.S., and Wyatt M.G. In situ silver impregnated Dacron replacement for an infected aortic stent graft: case report and review of the literature. EJVES Extra 5 (2003) 42-43
18. Ahearn D.G., Grace D.T., Jennings M.J., Borazjani R.N., Boles K.J., Rose L.J., et al. Effects of hydrogel/silver coatings on in vitro adhesion to catheters of bacteria associated with urinary tract infections. Curr Microbiol 41 (2000) 120-125
19. Gu J.-D., Belay B., and Mitchell R. Protection of catheter surfaces from adhesion of Pseudomonas aeruginosa by a combination of silver ions and lectins. World J Microbiol Biotechnol 17 (2001) 173-179
20. Gray J.E., Norton P.R., Alnounu R., Marolda C.L., Valvano M.A., and Griffiths K. Biological efficacy of electroless-deposited silver on plasma activated polyurethane. Biomaterials 24 (2003) 2758-2765
21. Batt M., Magne J.-L., Alric P., Muzj A., Ruotolo C., Ljungstrom K.-G., et al. In situ revascularization with silver-coated polyester grafts to treat aortic infection: early and midterm results. J Vasc Surg 38 (2003) 983-989
22. Batt M., Jean-Baptiste E., O'Connor S., Bouillanne P.-J., Haudebourg P., Hassen-Khodja R., et al. In situ revascularization for patients with aortic graft infection: a single centre experience with silver coated polyester grafts. Eur J Vasc Endovasc Surg 36 (2008) 182-188
23. Strathmann M., and Wingender J. Use of oxonol dye in combination with confocal laser scanning microscopy to monitor damage to S. aureus cells during colonisation of silver-coated vascular grafts. Int J Antimicrob Agents 24 (2004) 36-42
24. McLean R.J.C., Hussain A.A., Sayer M., Vincent P.J., Hughes D.J., and Smith T.J.N. Antibacterial activity of multilayer silver-copper surface films on catheter material. Can J Microbiol 39 (1993) 895-899
25. Cook G., Costerton J.W., and Darouiche R.O. Direct confocal microscopy studies of the bacterial colonization in vitro of a silver-coated heart valve sewing cuff. Int J Antimicrob Agents 13 (2000) 169-173
26. Schierholz J.M., Lucas L.J., Rump A., and Pulvever G. Efficacy of silver-coated medical devices. J Hosp Inf 40 (1998) 257-262
27. Schneider F., O'Connor S., and Becquemin J.P. Efficacy of collagen silver-coated polyester and rifampin-soaked vascular grafts to resist infection from MRSA and Escherichia coli in a dog model. Ann Vasc Surg 22 (2008) 815-821
28. Ginalska G., Osinska M., Uryniak A., Urbanik-Sypniewska T., Belcarz A., Rzeski W., et al. Antibacterial activity of gentamicin-bonded gelatin-sealed polyethylene terephthalate vascular prostheses. Eur J Vasc Endovasc Surg 29 (2005) 419-424
29. Ginalska G., Kowalczuk D., and Osinska M. Amikacin-loaded vascular prosthesis as an effective drug carrier. Int J Pharm 339 (2007) 39-46
30. Nordmann P., Naas T., Fortineau N., and Poirel L. Superbugs in the coming new decade; multidrug resistance and prospects for treatment of Stahpylococcus aureus, Enterococcus spp. and Pseudomonas aeruginosa in 2010. Curr Opin Microbiol 10 (2007) 436-440
31. Metan G., Zarakolu P., Çakir B., Hascelik G., and Uzun O. Clinical outcomes and therapeutic options of bloodstream caused by extended-spectrum β-lactamase-producing Escherichia coli. Int J Antimicrob Agents 26 (2005) 254-257
32. Ginalska G, Uryniak A, Łobarzewski J, Osinska M. A mode of immobilization of antibiotics containing primary amino groups on solid matrices sealed with protein. Polish Patent no P358934; WUP No 04/2009.
33. Naylor A.R., Hayes P.D., and Darke S. A prospective audit of complex wound and graft infections in Great Britain and Ireland: the emergence of MRSA. Eur J Vasc Endovasc Surg 21 (2001) 289-294
34. Goëau-Brissonnière O.A., Fabre D., Leflon-Guibout V., Di Centa I., Nicolas-Chanoine M.-H., and Coggia M. Comparison of the resistance to infection of rifampin-bonded gelatin-sealed and silver/collagen-coated polyester prostheses. J Vasc Surg 35 (2002) 1260-1263
35. Molski S., and Lukasiewicz A. Own superficial femoral vein versus silver bonded artificial graft in patients with vascular prosthesis infection in aorto-femoral position: treatment results comparison. Commentary of Prof. W. Majewski, MD. Polish J Surg 81 (2009) 165-171
36. Hardman S., Cope A., Swann A., Bell P.R.F., Naylor A.R., and Hayes P.D. An in vitro model to compare the antimicrobial activity of silver-coated versus rifampicin-soaked vascular grafts. Ann Vasc Surg 18 (2004) 308-313
37. Sieradzki K., Roberts R.B., Haber S.W., and Tomasz A. The development of vancomycin resistance in a patient with methicillin-resistant Staphylococcus aureus infection. N Engl J Med 340 (1999) 517-523