An LC-MS/MS method for determination of 3,6′-disinapoylsucrose in rat plasma and its application to a pharmacokinetic study

Biomedical Chromatography

Volumn 23, Issue 12, 2009, Pages 1326-1332

  Chen, Ying ^a   Liu, Xin Min ^a   Pan, Rui Le ^a   Wang, Geng Nan ^a   Fu, Ying ^a   Chang, Qi ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

3,6 disinapoylsucrose; LC MS MS; Pharmacokinetics; Polygala tenuifolia

Indexed keywords

BIOCHEMISTRY; BODY FLUIDS; ELECTROSPRAY IONIZATION; MASS SPECTROMETRY; MEDICINE; RATS;

3,6′-DISINAPOYLSUCROSE; ACTIVE COMPONENTS; ITS APPLICATIONS; LC-MS-MS; LC.MS/MS; NEUROPROTECTION; PHARMACOKINETIC STUDIES; POLYGALA TENUIFOLIUM; RAT PLASMA; TRADITIONAL CHINESE MEDICINE;

PHARMACOKINETICS;

3,6' DISINAPOYLSUCROSE; CHINESE DRUG; OLIGOSACCHARIDE; PLANT EXTRACT; POLYGALA TENUIFOLIA EXTRACT; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DETERMINATION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG ISOLATION; DRUG MEGADOSE; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MONITORING; NONHUMAN; PRECIPITATION; QUANTITATIVE ASSAY; RAT; SINGLE DRUG DOSE; SOLVENT EXTRACTION; SPRAGUE DAWLEY RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

POLYGALA TENUIFOLIA; RATTUS;

EID: 71649115384     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1257     Document Type: Article

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