Mycoflora and Co-occurrence of fumonisins and aflatoxins in freshly harvested corn in different regions of Brazil

International Journal of Molecular Sciences

Volumn 10, Issue 11, 2009, Pages 5090-5103

  Rocha, Liliana O ^a   Nakai, Viviane K ^a   Braghini, Raquel ^a   Reis, Tatiana A ^a   Kobashigawa, Estela ^a   Corrêa, Benedito ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aflatoxins; Aspergillus flavus; Corn (Zea mays L.); Fumonisins; Fusarium verticillioides; Mycoflora; Mycotoxins

Indexed keywords

AFLATOXIN B1; AFLATOXIN B2; AFLATOXIN G1; AFLATOXIN G2; FUMONISIN B1; FUMONISIN B2;

ARTICLE; ASPERGILLUS FLAVUS; BRAZIL; CORN; FUNGAL CONTAMINATION; FUSARIUM; FUSARIUM VERTICILLIOIDES; GRAIN; NONHUMAN;

AFLATOXINS; ASPERGILLUS FLAVUS; CORN (ZEA MAYS L.); FUMONISINS; FUSARIUM VERTICILLIOIDES; MYCOFLORA; MYCOTOXINS;

AFLATOXINS; BRAZIL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FUMONISINS; FUSARIUM; MYCOTOXINS; ZEA MAYS;

ASPERGILLUS FLAVUS; GIBBERELLA MONILIFORMIS; ZEA MAYS;

EID: 71649113599     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms10115090     Document Type: Article

References (58)

1. Companhia Nacional de Abastecimento (CONAB). Avaliação da safra 2007/2008. http://www.conab.gov.br/conabweb/index.php/, accessed November 12, 2008.
2. Pedrosa, A.V.B.; Dezen, R.B. O milho: Características do mercado e perspectivas. Preços Agric. 1991, 55, 1-4.
3. Almeida, A.P.; Sabino, M.; Fonseca, H.; Corrêa, B. Milho recém-colhido no Brasil: interação da microbiota fúngica, fatores abióticos e ocorrência de micotoxinas. Rev. Inst. Adolfo Lutz 2005, 64, 1-9.
4. Rheeder, J.P.; Marasas, W.F.O.; Thiel, P.G. Fusarium moniliforme and fumonisins in corn in relation to human esophageal cancer in Transkei. Phytopathology 1992, 82, 253-257.
5. Jaskiewics, K.; Van Renaburg, S.J.; Marasas, W.F.O.; Gelderblom, W.C.A. Carcinogenicity of Fusarium moniliforme culture material in rats. J. Natl. Cancer Inst. 1987, 78, 321-325.
6. Kellerman, T.S.; Marasas, W.F.O.; Thiel, P.G.; Gelderblom, W.C.A.; Cawood, M.; Coetzer, J.A. Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B1. Onderstepoort J. Vet. 1990, 57, 269-275.
7. Ledoux, D.R.; Brown, T.P.; Weibking, T.S.; Rottinghaus, G.E. Fumonisin toxicity in broiler chicks. J. Vet. Diagn. Invest. 1992, 4, 330-333.
8. Voss, K.A.; Chamberlain, W.S.; Bacon, C.W. Subchronic feeding study of the mycotoxin fumonisin B1. Nat. Toxins 1993, 1, 222-228.
9. Dilkin, P.; Zorzete, P.; Mallman, C.A.; Gomes, J.D.F.; Utiyama, C.E.; Oetting, L.L.; Corrêa, B. Toxicological effects of chronic low doses of aflatoxin B1 and fumonisin B1 containing Fusarium moniliforme culture material in weaned piglets. Food Chem. Toxicol. 2003, 41, 1345-1353. (Pubitemid 37289183)
10. 1. Nat. Toxins 1996, 4, 51-52.
11. Bucci, T.J.; Howard, P.C.; Tolleson, W.H.; LaBorde, J.B.; Hansen, D.K. Renal effects of fumonisin mycotoxins in animals. Toxicol. Pathol. 1998, 26, 160-164.
12. Gumprecht, L.A.; Marcucci, A.; Weigel, R.M.; Vesonder, R.F.; Riley, R.T.; Showker, J.L.; Showker, V.L.; Beasley, V.R.; Haschenk, W.M. Effects of intravenous fumonisin B1 in rabbits: Nephrotoxicity and sphingolipid alterations. Nat. Toxins 1995, 3, 395-403.
13. 2 and Fusarin C (Group 2B). In Monographs on the Evaluation of Carcinogenic Risks to Humans; IARC: Lyon, France, 1993; Vol.56, p. 445.
14. 1 (Group 2B). In Monographs on the Evaluation of Carcinogenic Risks to Humans; IARC: Lyon, France, 1993; Vol.56, p. 445.
15. BRAZIL. Ministry of Agriculture. Decree 183 of March 21, 1996. Art 1. Adopt MERCOSUR Technical Regulation on maximum levels of aflatoxins in milk, peanuts and corn, approved by resolution of the Southern Common Market in 56/94, of 01 January 1995. Published in the Official Gazette of 25 March 1996. http://extranet.agricultura.gov.br/sislegis-consulta/, accessed February 16, 2009.
16. BRAZIL. National Sanitary Surveillance Agency. Resolution 274 of October 15, 2002. Approves the Technical Regulation on maximum levels of aflatoxins in milk, peanut and corn. Published in the Official Gazette of 16 October 2002. http://www.anvisa.gov.br/e-legis/, accessed February 16, 2009.
17. European Mycotoxin Awareness Network. European Mycotoxin Awareness Network, a thematic network of 5 Framework Programme R&D call funded by the European Union; EMAN, 2000. http://www.mycotoxins.org/, accessed December 19, 2008.
18. Food and Drug Administration. Background paper in support of fumonisin levels in corn and corn products intended for human consumption. US Food and Drug Administration, Center for Food Safety and Applied Nutrition: Silver Spring, Maryland, USA, 2001. http://vm.cfsan.fda.gov/~dms/fumonbg1.html/, accessed February 10, 2009.
19. Moreno, E.C.; Garcia, G.T.; Ono, M.A.; Vizoni, E.; Kawamura, O.; Hirooka, E.Y.; Ono, E.Y.S. Co-occurrence of mycotoxins in corn samples from the Northern region of Paraná State, Brazil. Food Chem. 2009, 116, 220-226.
20. Delp, R.B.; Stewell, L.J.; Marois, J.J. Evaluation of field sampling techniques for estimation of disease incidence. Phytopathology 1986, 76, 1299-1305.
21. Pitt, J.I.; King, A.D.; Hocking, A.D. Dichloran-rose bengal medium for enumeration and isolation of molds from foods. Appl. Environ. Microbiol. 1979, 37, 959-964.
22. Raper, K.B.; Fennell, D.I. The Genus Aspergillus, 1st ed.; Williams & Wilkins: Baltimore, MD, USA, 1965; p. 686.
23. Pitt, J.I.; Hocking, A.D. Fungi and Food Spoilage, 2nd ed.; Chapman & Hall: London, UK, 1997; p. 592.
24. Nelson, P.E.; Touson, T.A.; Marasas, W.F.O. Fusarium Species. An Illustrated Manual for Identification; The Pennsylvania State University Press: University Park, PA, USA, 1983; p. 193.
25. Leslie, J.F.; Summerell, B.A. The Fusarium Laboratory Manual, 1st ed.; Blackwell Publishing: Ames, Iowa, USA, 2006; p. 388.
26. 2 in corn and corn flakes by liquid chromatography with immunoaffinity column cleanup: collaborative study. J. AOAC Int. 2001, 84, 1828-1837.
27. Soares, L.M.V.; Rodriguez-Amaya, D.B. Survey of aflatoxins, ochratoxin A, zearalenone and sterigmatocystin in some Brazilian foods by using multi-toxin thin layer chromatographic method. J. Assoc. Off. Chem. 1989, 72, 22-26.
28. Scott, P.M. Natural poisons. In Association of Official Analytical Chemists. Official Methods of Analysis, 15th ed.; Helrich, K., Ed.; AOAC: Arlington, Virginia, USA, 1990; pp. 1184-1213.
29. Rigby, R.A.; Stasinopoulos, D.M. Generalized additive models for location, scale and shape. J. R. Statist. Soc. C: Appl. Stat. 2005, 54, 507-554. (Pubitemid 40659551)
30. Neter, J.; Kutner, M.K.; Nachtsheim, C.J.; Wasserman, W. Applied Linear Statistical Models, 4th ed.; Irwin: Chicago, Illinois, USA, 1996; p. 1408.
31. Lillehoj, E.B.; Kwolek, W.F.; Guthrie, W.D.; Barry, D.; McMillian, W.W.; Widstron, N.W. Aflatoxin accumulation in preharvest maize (Zea mays L.) kernels, interactions of 3 fungal species in European corn borer Ostrinia nubilis and 2 hybrids. Plant Soil 1982, 65, 95-102.
32. Deacon, J.W. Introduction to Modern Mycology, 2nd ed.; Blackwell Sci. Publishing: London, UK, 1984; p. 238.
33. Marín, S.; Sanchis, V.; Arnau, F. Colonisation and competitiveness of Aspergillus and Penicillium species on maize grain in the presence of Fusarium moniliforme and Fusarium proliferatum. Int. J. Food Microbiol. 1998, 45, 107-117.
34. Cuero, R.G.; Lillehoj, E.B.; Kwolek, W.F.; Zuber, M.S. Mycoflora and aflatoxin and preharvest maize kernels of varied endosperm type. In Trichothecene and Other Mycotoxins, 1st ed.; Lacey, J., Ed.; John Wiley & Sons, Ltd.: New York, NY, USA, 1985; pp. 109-111.
35. Hennigen, M.R.; Valente Soares, L.M.; Sanchez, S.; Di Benedetto, N.M.; Longhi, A.; Eyherabide, G.; Torroba, J.; Zanelli, M. Fumonisins in corn hybrids grown in Argentina for 2 consecutive seasons. In Proceedings of the 10th International IUPAC Symposium on Mycotoxins and Phytotoxins, Guaruja, Brazil, 21-25 May 2000; De Koe, W.J., Samson, R.A., Van Egmond, H.P., Gilbert, J., Sabino, M., Eds.; IUPAC: Guaruja, Brazil, 2000; pp. 331-339.
36. Gong, H.Z.; Ji, R.; Li, Y.X.; Zhang, H.Y.; Li, B.; Zhao, Y.; Sun, L.; Yu, F.; Yang, J. Occurrence of fumonisin in corn from the main corn - Producing areas of China. Mycopathologia 2009, 167, 31-36.
37. Hirooka, E.Y.; Yamaguchi, M.M.; Aoyama, S.; Sugiura, Y.; Ueno, Y. The natural occurrence of fumonisins in Brazilian corn kernels. Food Addit. Contam. 1996, 13, 173-183. (Pubitemid 26121726)
38. Camargos, S.M.; Soares, L.M.V.; Sawazaki, E.; Bolonhezi, D.; Castro, J.L.; Bortolleto, N. Fumonisins in corn cultivars in the State of São Paulo. Br. J. Microbiol. 2000, 31, 226-229. (Pubitemid 41124413)
39. Orsi, R.B.; Corrêa, B.; Pozzi, C.R.; Schammass, E.; Nogueira, J.R.; Dias, S.M.C.; Malozzi, M. Mycoflora and occurrence of fumonisins in freshly harvest and stored hybrid maize. J. Stor. Prod. Res. 2000, 36, 75-87. (Pubitemid 30044798)
40. Mallman, C.A.; Santurio, J.M.; Dilkin, P. Fumonisin B1 in cereals and feeds from southern Brazil. Arq. Inst. Biol. 2001, 68, 41-45.
41. Ono, E.Y.S.; Ono, M.A.; Funo, F.Y.; Medina, A.E.; Oliveira, T.C.R.M.; Kawamura, O.; Ueno, Y.; Hirooka, E. Evaluation of fumonisin-aflatoxin co-occurrence in Brazilian corn hybrids by ELISA. Food Addit. Contam. 2001, 18, 719-729. (Pubitemid 32677949)
42. Almeida, A.P.; Fonseca, H.; Fancelli, A.L.; Direito, G.M.; Ortega, E.M.; Corrêa, B. Mycoflora and fumonisin contamination in Brazilian corn from sowing to harvest. J. Agric. Food Chem. 2002, 50, 3877-3882. (Pubitemid 34640721)
43. Rodriguez-Amaya, D.B.; Sabino, M. Mycotoxin research in Brazil: the last decade in review. Brazil J. Microbiol. 2002, 33, 1-11. (Pubitemid 40747412)
44. Van der Westhuizen, L.; Shephard, G.S.; Scussel, V.M.; Costa, L.L.F.; Vismer, H.F.; Rheeder, J.P.; Marasas, W.F.O. Fumonisin contamination and Fusarium incidence in corn from Santa Catarina, Brazil. J. Agric. Food Chem. 2003, 51, 5574-5578.
45. Ono, E.Y.S.; Fungaro, M.H.P.; Sofia, S.H.; Figueira, E.L.Z.; Gerage, A.C.; Ichione, M.; Sugiura, Y.; Ueno, Y.; Hirooka, E.Y. Trends of fumonisin contamination and animal intoxication through monitoring 1991 to 1997 corn crop in the State of Paraná, Brazil. Mycopathologia 2004, 158, 451-455.
46. Hassegawa, R.H.; Fonseca, H.; Fancelli, A.L.; Silva, V.N.; Schammass, E.A.; Reis, T.A.; Corrêa, B. Influence of macro-and micronutrient fertilization on fungal contamination and fumonisin production in corn grains. Food Control 2008, 19, 36-43. (Pubitemid 47324101)
47. Ono, E.Y.S.; Silva, M.; Hashimoto, E.H.; Vizoni, E.; Kawamura, O.; Sugiura, Y.; Hirooka, E.Y. Mycotoxicological quality evaluation of corn samples used by processing industries in the Northern region of Paraná State, Brazil. Food Addit. Contam. 2008, 25, 1-8.
48. McCullagh, P.; Nelder, J.A. Generalized Linear Models, 2nd ed.; Chapman and Hall: London, UK, 1989; p. 238.
49. Heller, G.; Stasinopoulos, M.; Rigby, B. The zero-adjusted inverse Gaussian distribution as a model for insurance claims. In Proceedings of the 21st International Workshop on Statistical Modelling, Galway, Ireland, 3-7 July, 2006; pp. 226-233.
50. Pozzi, C.R.; Corrêa, B.; Gambale, W.; Paula, C.R.; Chacon-Reche, N.O.; Meirelles, M.C.A. Postharvest and stored corn in Brazil: Mycoflora interaction, abiotic factors and mycotoxins occurrence. Food Addit. Contam. 1995, 12, 313-319.
51. Salay, E.; Mercadante, A.Z. Mycotoxins in Brazilian corn for animal feed: Occurrence and incentives for the private sector to control the level of contamination. Food Control 2002, 13, 87-92.
52. Bautista, A.R.P.; Oliveira, M.Z.A.; Miranda, M.S.; Sales, L.A. Aflatoxinas em grãos de milho armazenado no Estado da Bahia. Rev. Soc. Bras. Toxicol. 1989, 2, 24-25.
53. Sabino, M.; Prado, G.; Ionamata, I.O.; Pedroso, M.O.; Garcia, R.V. Natural occurrence of aflatoxins and zearalenone in maize in Brazil. Food Addit. Contam. 1989, 6, 327-331.
54. Henningen, M.R.; Dick, T. Incidence and abundance of mycotoxins in maize in Rio Grande do Sul, Brazil. Food Addit. Contamin. 1995, 12, 677-681.
55. Gloria, E.M.; Fonseca, H.; Souza, I.M. Occurrence of mycotoxins in maize delivered to the food industry in Brazil. Trop. Sci. 1997, 37, 107-110.
56. Côrtes, N.A.; Neto, D.C.; Corrêa, B. Ocorrência de aflatoxinas em milho produzido pelo sistema de cultivo, em comunidades de agricultura familiar, no estado do Mato Grosso. Rev. Hig. Alim. 2000, 14, 16-26.
57. Lacey, J.; Ramakrishna, N.; Hamer, A.; Magan, N.; Marfleet, C. Grain fungi. In Handbook of Applied Mycology: Foods and Feeds; Bhatnagar, D., Lillehoj, E.B., Arora, D.K., Eds.; Marcel Dekker: New York, NY, USA, 1992; pp. 121-177.
58. Zorzete, P.; Castro, R.S.; Pozzi, C.R.; Israel, A.L.M.; Fonseca, H.; Yanaguibashi, G.; Corrêa, B. Relative populations and toxin production by Aspergillus flavus and Fusarium verticillioides in artificially inoculated corn at various stages of development under field conditions. J. Sci. Food. Agric. 2008, 88, 48-55.