Effect of polymer chemistry and fabrication method on protein release and stability from polyanhydride microspheres

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 91, Issue 2, 2009, Pages 938-947

  Lopac, Senja K ^a   Torres, Maria P ^a   Wilson Welder, Jennifer H ^b   Wannemuehler, Michael J ^b   Narasimhan, Balaji ^a  

^a Iowa State University of Science and Technology   (United States)

^b IOWA STATE UNIVERSITY   (United States)

Author keywords

Cryogenic atomization; Microspheres; Polyanhydrides; Protein stability; Release kinetics

Indexed keywords

AMPHIPHILICS; BURST RELEASE; DOUBLE EMULSIONS; FABRICATION METHOD; NON-AQUEOUS; OVALBUMINS; POLYANHYDRIDE MICROSPHERES; POLYANHYDRIDES; POLYMER CHEMISTRY; PROTEIN RELEASE; PROTEIN STABILITY; PROTEIN STRUCTURES; RELEASE KINETICS; SEBACIC ACID; WESTERN-BLOT ANALYSIS;

ATOMIZATION; CRYOGENICS; EMULSIFICATION; FABRICATION; HEXANE; JETS; MICROSPHERES; POLYMERS; STABILITY;

PROTEINS;

1,6 BIS(4 CARBOXYPHENOXY)HEXANE; 1,8 BIS(4 CARBOXYPHENOXY) 3,6 DIOXAOCTANE; EPITOPE; HEXANE; MICROSPHERE; OCTANE; OIL; OVALBUMIN; POLYANHYDRIDE; POLYMER; PROTEIN; SEBACIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CHEMISTRY; EMULSION; ENCAPSULATION; KINETICS; NEBULIZATION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN STRUCTURE; SOLID; WESTERN BLOTTING;

BIOCOMPATIBLE MATERIALS; BLOTTING, WESTERN; DECANOIC ACIDS; DICARBOXYLIC ACIDS; DRUG CARRIERS; DRUG STABILITY; HEXANES; KINETICS; MICROSPHERES; OVALBUMIN; PARTICLE SIZE; POLYANHYDRIDES; POLYETHYLENE GLYCOLS; PROTEINS; SOLUBILITY;

EID: 71649112739     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31478     Document Type: Article

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