Use of polyetheretherketone spacer and recombinant human bone morphogenetic protein-2 in the cervical spine: a radiographic analysis

Spine Journal

Volumn 9, Issue 12, 2009, Pages 959-966

  Klimo Jr , Paul ^a   Peelle, Michael W ^a  

^a WRIGHT PATTERSON AIR FORCE BASE   (United States)

Author keywords

Anterior cervical discectomy and fusion; Bone morphogenetic protein; Heterotopic bone; Polyetheretherketone; Radiographic analysis

Indexed keywords

ADULT; AGED; ARTICLE; BONE GRAFT; BONE GROWTH; CERVICAL SPINE; CERVICAL SPONDYLOSIS; CLINICAL ARTICLE; EDEMA; FEMALE; HUMAN; IMPLANT; INTERVERTEBRAL DISKECTOMY; MALE; OSTEOLYSIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PSEUDARTHROSIS; RECURRENT LARYNGEAL NERVE PALSY; SPINE FUSION;

ADULT; AGED; BONE CYSTS; BONE MORPHOGENETIC PROTEINS; BONE PLATES; CERVICAL VERTEBRAE; FEMALE; HUMANS; KETONES; MALE; MIDDLE AGED; OSSEOINTEGRATION; OSSIFICATION, HETEROTOPIC; OSTEOLYSIS; POLYETHYLENE GLYCOLS; POSTOPERATIVE COMPLICATIONS; PROSTHESIS FAILURE; PSEUDARTHROSIS; RECOMBINANT PROTEINS; SPINAL FUSION; TRANSFORMING GROWTH FACTOR BETA;

EID: 71649109037     PISSN: 15299430     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spinee.2009.05.008     Document Type: Article

References (24)

1. Burkus J.K., Transfeldt E.E., Kitchel S.H., et al. Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2. Spine 27 (2002) 2396-2408
2. Mummaneni P.V., Pan J., Haid R.W., and Rodts G.E. Contribution of recombinant human bone morphogenetic protein-2 to the rapid creation of interbody fusion when used in transforaminal lumbar interbody fusion: a preliminary report. Invited submission from the Joint Section Meeting on Disorders of the Spine and Peripheral Nerves, March 2004. J Neurosurg Spine 1 (2004) 19-23
3. Haid Jr. R.W., Branch Jr. C.L., Alexander J.T., and Burkus J.K. Posterior lumbar interbody fusion using recombinant human bone morphogenetic protein type 2 with cylindrical interbody cages. Spine J 4 (2004) 527-538 discussion 38-9
4. Perri B., Cooper M., Lauryssen C., and Anand N. Adverse swelling associated with use of rh-BMP-2 in anterior cervical discectomy and fusion: a case study. Spine J 7 (2007) 235-239
5. Vaidya R., Carp J., Sethi A., et al. Complications of anterior cervical discectomy and fusion using recombinant human bone morphogenetic protein-2. Eur Spine J 16 (2007) 1257-1265
6. Buttermann G.R. Prospective nonrandomized comparison of an allograft with bone morphogenic protein versus an iliac-crest autograft in anterior cervical discectomy and fusion. Spine J 8 (2008) 426-435
7. Shields L.B., Raque G.H., Glassman S.D., et al. Adverse effects associated with high-dose recombinant human bone morphogenetic protein-2 use in anterior cervical spine fusion. Spine 31 (2006) 542-547
8. Smucker J.D., Rhee J.M., Singh K., et al. Increased swelling complications associated with off-label usage of rhBMP-2 in the anterior cervical spine. Spine 31 (2006) 2813-2819
9. Tumialan L.M., Pan J., Rodts G.E., and Mummaneni P.V. The safety and efficacy of anterior cervical discectomy and fusion with polyetheretherketone spacer and recombinant human bone morphogenetic protein-2: a review of 200 patients. J Neurosurg Spine 8 (2008) 529-535
10. Vaidya R., Weir R., Sethi A., et al. Interbody fusion with allograft and rhBMP-2 leads to consistent fusion but early subsidence. J Bone Joint Surg Br 89 (2007) 342-345
11. Wong D.A., Kumar A., Jatana S., et al. Neurologic impairment from ectopic bone in the lumbar canal: a potential complication of off-label PLIF/TLIF use of bone morphogenetic protein-2 (BMP-2). Spine J 8 (2008) 1011-1018
12. Joseph V., and Rampersaud Y.R. Heterotopic bone formation with the use of rhBMP2 in posterior minimal access interbody fusion: a CT analysis. Spine 32 (2007) 2885-2890
13. Vaidya R., Sethi A., Bartol S., et al. Complications in the use of rhBMP-2 in PEEK cages for interbody spinal fusions. J Spinal Disord Tech 21 (2008) 557-562
14. Kulkarni A.G., Hee H.T., and Wong H.K. Solis cage (PEEK) for anterior cervical fusion: preliminary radiological results with emphasis on fusion and subsidence. Spine J 7 (2007) 205-209
15. Celik S.E., Kara A., and Celik S. A comparison of changes over time in cervical foraminal height after tricortical iliac graft or polyetheretherketone cage placement following anterior discectomy. J Neurosurg Spine 6 (2007) 10-16
16. Cho D.Y., Liau W.R., Lee W.Y., et al. Preliminary experience using a polyetheretherketone (PEEK) cage in the treatment of cervical disc disease. Neurosurgery 51 (2002) 1343-1349 discussion 1349-50
17. Mastronardi L., Ducati A., and Ferrante L. Anterior cervical fusion with polyetheretherketone (PEEK) cages in the treatment of degenerative disc disease. Preliminary observations in 36 consecutive cases with a minimum 12-month follow-up. Acta Neurochir (Wien) 148 (2006) 307-312 discussion 312
18. Baskin D.S., Ryan P., Sonntag V., et al. A prospective, randomized, controlled cervical fusion study using recombinant human bone morphogenetic protein-2 with the CORNERSTONE-SR allograft ring and the ATLANTIS anterior cervical plate. Spine 28 (2003) 1219-1224 discussion 1225
19. Dickerman R.D., Reynolds A.S., Morgan B.C., et al. rh-BMP-2 can be used safely in the cervical spine: dose and containment are the keys!. Spine J 7 (2007) 508-509
20. Boakye M., Mummaneni P.V., Garrett M., et al. Anterior cervical discectomy and fusion involving a polyetheretherketone spacer and bone morphogenetic protein. J Neurosurg Spine 2 (2005) 521-525
21. Dickerman R.D., Reynolds A., and Morgan B. Calcium phosphate silicate for spinal fusion: a good alternative to bone morphogenetic protein-2!. Spine J 8 (2008) 1046-1047
22. Barnes B., Boden S.D., Louis-Ugbo J., et al. Lower dose of rhBMP-2 achieves spine fusion when combined with an osteoconductive bulking agent in non-human primates. Spine 30 (2005) 1127-1133
23. Lewandrowski K.U., Nanson C., and Calderon R. Vertebral osteolysis after posterior interbody lumbar fusion with recombinant human bone morphogenetic protein 2: a report of five cases. Spine J 7 (2007) 609-614
24. McClellan J.W., Mulconrey D.S., Forbes R.J., and Fullmer N. Vertebral bone resorption after transforaminal lumbar interbody fusion with bone morphogenetic protein (rhBMP-2). J Spinal Disord Tech 19 (2006) 483-486