Preparation of new nitrogen-bridged heterocycles 67.1 syntheses of α,α′-bis[(thieno[3,4-b]indolizin-3-yl)thio]-o-, m-, and p-xylene derivatives and their conformational structures

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 12, 2009, Pages 1385-1390

  Kakehi, Akikazu ^a   Suga, Hiroyuki ^a   Okumura, Yukihisa ^a   Shinohara, Masatoshi ^a   Kako, Tomonao ^a   Sekiguchi, Takeshi ^a   Shiro, Motoo ^b  

^a SHINSHU UNIVERSITY   (Japan)

^b RIGAKU CORPORATION   (Japan)

Author keywords

Arene arene interaction; Cyclization; Sulfide linkage; Thieno 3,4 b indolizine; X ray analysis

Indexed keywords

3 (3,5 DIMETHYL 1 PYRIDINIO)THIOPHENE 2 THIOLATE; 5 (4 BROMOBENZOYL 3 (3,5 DIMETHYL 1 PYRIDINIO) 4 (ETHOXYCARBONYL METHYL)THIOPENE 2 THIOLATE; 5 (4 CHLOROBENZOYL 3 (3,5 DIMETHYL 1 PYRIDINIO) 4 (ETHOXYCARBONYLMETHYL)THIOPHENE 2 THIOLATE; 5 BENZOYL 3 (3,5 DIMETHYL 1 PYRIDINIO) 4 (ETHOXYCARBONYLMETHYL)THIOPHENE 2 THIOLATE; ALPHA,ALPHA' BIS[(1 (4 BROMOBENZOYL) 9 ETHOXYCARBONYL 6,8 DIMETHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; ALPHA,ALPHA' BIS[(1 (4 BROMOBENZOYL) 9 ETHOXYCARBONYL 7 METHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]M XYLENE; ALPHA,ALPHA' BIS[(1 (4 BROMOBENZOYL) 9 ETHOXYCARBONYL 7 METHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; ALPHA,ALPHA' BIS[(1 (4 BROMOBENZOYL) 9 ETHOXYCARBONYLTHIENO [3,4 B]INDOLIZIN 3 YL)THIO]M XYLENE; ALPHA,ALPHA' BIS[(1 (4 BROMOBENZOYL) 9 ETHOXYCARBONYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]P XYLENE; ALPHA,ALPHA' BIS[(1 (4 CHLOROBENZOYL) 9 ETHOXYCARBONYL 6,8 DIMETHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]M XYLENE; ALPHA,ALPHA' BIS[(1 (4 CHLOROBENZOYL) 9 ETHOXYCARBONYL 6,8 DIMETHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; ALPHA,ALPHA' BIS[(1 (4 CHLOROBENZOYL) 9 ETHOXYCARBONYL 7 METHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]M XYLENE; ALPHA,ALPHA' BIS[(1 (4 CHLOROBENZOYL) 9 ETHOXYCARBONYL 7 METHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; ALPHA,ALPHA' BIS[(1 (4 CHLOROBENZOYL) 9 ETHOXYCARBONYL 7 METHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]P XYLENE; ALPHA,ALPHA' BIS[(1 (4 CHLOROBENZOYL) 9 ETHOXYCARBONYLTHIENO [3,4 B]INDOLIZIN 3 YL)THIO]M XYLENE; ALPHA,ALPHA' BIS[(1 (4 CHLOROBENZOYL) 9 ETHOXYCARBONYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]P XYLENE; ALPHA,ALPHA' BIS[(1 (4CHLOROBENZOYL) 9 ETHOXYCARBONYL 6,8 DIMETHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]P XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL 9 ETHOXYCARBONYL 6,8 DIMETHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL 9 ETHOXYCARBONYL 6,8 DIMETHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]P XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL 9 ETHOXYCARBONYL 7 METHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]M XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL 9 ETHOXYCARBONYL 7 METHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL 9 ETHOXYCARBONYL 7 METHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]P XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL 9 ETHOXYCARBONYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL 9 ETHOXYCARBONYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]P XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL) 9 ETHOXYCARBONYL 6,8 DIMETHYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]M XYLENE; ALPHA,ALPHA' BIS[(1 BENZOYL) 9 ETHOXYCARBONYLTHIENO [3,4 B]INDOLIZIN 3 YL)THIO]M XYLENE; ALPHA,ALPHA' BIS[1 (4 BROMOBENZOYL) 9 ETHOXYCARBONYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; ALPHA,ALPHA' BIS[1 (4 CHLOROBENZOYL) 9 ETHOXYCARBONYLTHIENO[3,4 B]INDOLIZIN 3 YL)THIO]O XYLENE; HYDROCARBON; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALKYLATION; ARTICLE; CHEMICAL INTERACTION; CHEMICAL STRUCTURE; DEHYDROGENATION; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; ULTRAVIOLET RADIATION; X RAY ANALYSIS;

CRYSTALLOGRAPHY, X-RAY; HETEROCYCLIC COMPOUNDS; INDOLIZINES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NITROGEN; SULFHYDRYL COMPOUNDS; XYLENES;

EID: 71649103611     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.1385     Document Type: Article

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