메뉴 건너뛰기




Volumn 101, Issue 12, 2009, Pages 1961-1971

Epoetin-Β treatment in patients with cancer chemotherapy-induced anaemia: The impact of initial haemoglobin and target haemoglobin levels on survival, tumour progression and thromboembolic events

Author keywords

Anaemia; Epoetin ; Survival

Indexed keywords

ANTINEOPLASTIC AGENT; HEMOGLOBIN; RECOMBINANT ERYTHROPOIETIN;

EID: 71649091673     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605255     Document Type: Article
Times cited : (40)

References (51)
  • 1
    • 42949174250 scopus 로고    scopus 로고
    • Effect of treatment with epoetin beta on survival, tumour progression and thromboembolic events in patients with metastatic cancer: An updated meta-analysis of 12 randomized controlled studies including 2301 patients
    • Aapro M, Scherhag A, Burger HU (2008a) Effect of treatment with epoetin beta on survival, tumour progression and thromboembolic events in patients with metastatic cancer: an updated meta-analysis of 12 randomized controlled studies including 2301 patients. Br J Cancer 99(1): 14-22
    • (2008) Br J Cancer , vol.99 , Issue.1 , pp. 14-22
    • Aapro, M.1    Scherhag, A.2    Burger, H.U.3
  • 3
    • 70350578941 scopus 로고    scopus 로고
    • What is the impact of anti-thrombotic therapy and risk factors on the frequency of thrombo-vascu-lar events in patients with metastatic breast cancer receiving epoetin beta?
    • epub ahead of print, 29 July 2009, doi:10.1016/j.ejca.2009.06.31
    • Aapro M, Barnadas A, Leonard RC, Marangolo M, Untch M, Ukarma L, Burger H-U, Scherhag A, Osterwalder B (2009) What is the impact of anti-thrombotic therapy and risk factors on the frequency of thrombo-vascu-lar events in patients with metastatic breast cancer receiving epoetin beta? Eur J Cancer, epub ahead of print, 29 July 2009, doi:10.1016/j.ejca.2009.06.31
    • (2009) Eur J Cancer
    • Aapro, M.1    Barnadas, A.2    Leonard, R.C.3    Marangolo, M.4    Untch, M.5    Ukarma, L.6    Burger, H.-U.7    Scherhag, A.8    Osterwalder, B.9
  • 4
    • 49249083689 scopus 로고    scopus 로고
    • September 2007 Update on EORTC guidelines and anemia management with erythropoiesis-stimulating agents
    • Aapro M, Link H (2008) September 2007 Update on EORTC guidelines and anemia management with erythropoiesis-stimulating agents. The Oncologist 13(suppl 3): 33-36
    • (2008) The Oncologist , vol.13 , Issue.SUPPL 3 , pp. 33-36
    • Aapro, M.1    Link, H.2
  • 6
    • 0036720851 scopus 로고    scopus 로고
    • Immunohistochem-ical expression of erythropoietin and erythropoietin receptor in breast carcinoma
    • Acs G, Zhang PJ, Rebbeck TR, Acs P, Verma A (2002) Immunohistochem-ical expression of erythropoietin and erythropoietin receptor in breast carcinoma. Cancer 95(5): 969-981
    • (2002) Cancer , vol.95 , Issue.5 , pp. 969-981
    • Acs, G.1    Zhang, P.J.2    Rebbeck, T.R.3    Acs, P.4    Verma, A.5
  • 7
    • 0038042011 scopus 로고    scopus 로고
    • Risk factors for venous thromboembo-lism
    • Anderson FA, Spencer FA (2003) Risk factors for venous thromboembo-lism. Circulation 107: I-9-I-16
    • (2003) Circulation , vol.107
    • Anderson, F.A.1    Spencer, F.A.2
  • 8
    • 0037738124 scopus 로고    scopus 로고
    • Erythropoietin enhances radiation treatment efficacy in patients with pelvic malignancies: Final results of a randomized phase III study
    • Antonadou D, Cardamakis E, Puglisi M (2001) Erythropoietin enhances radiation treatment efficacy in patients with pelvic malignancies: final results of a randomized phase III study. Eur J Cancer 37(Suppl 6): A530
    • (2001) Eur J Cancer , vol.37 , Issue.SUPPL 6
    • Antonadou, D.1    Cardamakis, E.2    Puglisi, M.3
  • 10
    • 0032572913 scopus 로고    scopus 로고
    • The effects of normal as compared with low haematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
    • Besarab A, Bolton WK, Browne JK, Egrie JC, Nissenson AR, Okamoto DM, Schwab SJ, Goodkin DA (1998) The effects of normal as compared with low haematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med 339: 584-590
    • (1998) N Engl J Med , vol.339 , pp. 584-590
    • Besarab, A.1    Bolton, W.K.2    Browne, J.K.3    Egrie, J.C.4    Nissenson, A.R.5    Okamoto, D.M.6    Schwab, S.J.7    Goodkin, D.A.8
  • 11
    • 28944434527 scopus 로고    scopus 로고
    • Anaemia in cancer patients: Pathophysiology, incidence and treatment
    • Bokemeyer C, Oechsle K, Hartmann J-T (2005) Anaemia in cancer patients: pathophysiology, incidence and treatment. Eur J Clin Invest 35(Suppl 3): 26-31
    • (2005) Eur J Clin Invest , vol.35 , Issue.SUPPL 3 , pp. 26-31
    • Bokemeyer, C.1    Oechsle, K.2    Hartmann, J.-T.3
  • 12
    • 33846339172 scopus 로고    scopus 로고
    • EORTC guidelines for the use of erythropoietic proteins in anaemic patients with cancer: 2006 update
    • ̈ Bokemeyer C, Aapro MS, Courdi A, Foubert J, Link H, Osterborg A, Repetto L, Soubeyran P, European Organization for research and Treatment of Cancer (EORTC) Taskforce for the Elderly (2007) EORTC guidelines for the use of erythropoietic proteins in anaemic patients with cancer: 2006 update. Eur J Cancer 43: 258-270
    • (2007) Eur J Cancer , vol.43 , pp. 258-270
    • Bokemeyer, C.1    Aapro, M.S.2    Courdi, A.3    Foubert, J.4    Link, H.5    Osterborg, A.6    Repetto, L.7    Soubeyran, P.8
  • 17
    • 0038369006 scopus 로고    scopus 로고
    • Impact of epoetin beta on quality of life in patients with malignant disease
    • Boogaerts M, Coiffier B, Kainz C, Epoetin Beta QOL Working Group (2003) Impact of epoetin beta on quality of life in patients with malignant disease. Br J Cancer 88: 988-995
    • (2003) Br J Cancer , vol.88 , pp. 988-995
    • Boogaerts, M.1    Coiffier, B.2    Kainz, C.3
  • 18
    • 0035875880 scopus 로고    scopus 로고
    • Anemia as an independent prognostic factor for survival in patients with cancer: A systematic, quantitative review
    • Caro JJ, Salas M, Ward A, Goss G (2001) Anemia as an independent prognostic factor for survival in patients with cancer: a systematic, quantitative review. Cancer 91: 2214-2221
    • (2001) Cancer , vol.91 , pp. 2214-2221
    • Caro, J.J.1    Salas, M.2    Ward, A.3    Goss, G.4
  • 20
    • 0037102975 scopus 로고    scopus 로고
    • Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy
    • Crawford J, Cella D, Cleeland CS, Cremieux PY, Demetri GD, Sarokhan BJ, Slavin MB, Glaspy JA (2002) Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy. Cancer 95: 888-895
    • (2002) Cancer , vol.95 , pp. 888-895
    • Crawford, J.1    Cella, D.2    Cleeland, C.S.3    Cremieux, P.Y.4    Demetri, G.D.5    Sarokhan, B.J.6    Slavin, M.B.7    Glaspy, J.A.8
  • 21
    • 0035400246 scopus 로고    scopus 로고
    • Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx
    • DOI 10.1016/S0360-3016(01)01488-2, PII S0360301601014882
    • Glaser CM, Millesi W, Kornek GV, Long S, Schull B, Watzinger F, Selzer E, Lavey RS (2001) Impact of hemoglobin level and use of recombinant erythropoietin on efficacy of preoperative chemoradiation therapy for squamous cell carcinoma of the oral cavity and oropharynx. Int J Radiat Oncol Biol Phys 50: 705-715 (Pubitemid 32519598)
    • (2001) International Journal of Radiation Oncology Biology Physics , vol.50 , Issue.3 , pp. 705-715
    • Glaser, C.M.1    Millesi, W.2    Kornek, G.V.3    Lang, S.4    Schull, B.5    Watzinger, F.6    Selzer, E.7    Lavey, R.S.8
  • 23
    • 71649098274 scopus 로고    scopus 로고
    • Letter
    • Janecka IP (2004) Letter. Lancet 363: 992
    • (2004) Lancet , vol.363 , pp. 992
    • Janecka, I.P.1
  • 25
    • 0031962845 scopus 로고    scopus 로고
    • Randomized multicenter trial of the influence of recombinant human erythropoietin on intraoperative and postoperative transfusion need in anaemic patients undergoing right hemicolectomy for carcinoma
    • Kettelhack C, Hones C, Messinger D, Schlag PM (1998) Randomized multicenter trial of the influence of recombinant human erythropoietin on intraoperative and postoperative transfusion need in anaemic patients undergoing right hemicolectomy for carcinoma. Br J Surg 85: 63-67
    • (1998) Br J Surg , vol.85 , pp. 63-67
    • Kettelhack, C.1    Hones, C.2    Messinger, D.3    Schlag, P.M.4
  • 27
    • 1442307804 scopus 로고    scopus 로고
    • Erythropoietin to treat anaemia in patients with head and neck cancer [letter]
    • Leyland-Jones B, Mahmud S (2004) Erythropoietin to treat anaemia in patients with head and neck cancer [letter]. Lancet 363: 80
    • (2004) Lancet , vol.363 , pp. 80
    • Leyland-Jones, B.1    Mahmud, S.2
  • 29
    • 0035367087 scopus 로고    scopus 로고
    • Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: Results of a randomized, double-blind, placebo-controlled clinical trial
    • Littlewood TJ, Bajetta E, Nortier JW, Vercammen E, Rapaport B, Epoetin Alfa Study Group (2001) Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled clinical trial. J Clin Oncol 19: 2865-2874
    • (2001) J Clin Oncol , vol.19 , pp. 2865-2874
    • Littlewood, T.J.1    Bajetta, E.2    Nortier, J.W.3    Vercammen, E.4    Rapaport, B.5
  • 31
    • 65449169609 scopus 로고    scopus 로고
    • (darbepoetin alfa) Amgen, Inc. and Procrit (epoetin alfa) Ortho Biotech, L.P., for the Treatment of Anemia Associated with Cancer Chemotherapy accessed 15 September 2009
    • Luksenburg H, Weir A, Wager R (2004) FDA Briefing Document: Safety Concerns Associated with Aranesp (darbepoetin alfa) Amgen, Inc. and Procrit (epoetin alfa) Ortho Biotech, L.P., for the Treatment of Anemia Associated with Cancer Chemotherapy, http://www.fda.gov/ohrms/ dockets/ac/cder04.html#oncologic, accessed 15 September 2009
    • (2004) FDA Briefing Document: Safety Concerns Associated with Aranesp
    • Luksenburg, H.1    Weir, A.2    Wager, R.3
  • 32
    • 0035942272 scopus 로고    scopus 로고
    • Erythropoietin induces tumour progression and antitumour immune responses in murine myeloma models
    • Mittelman M, Neumann D, Peled A, Kanter P, Haren-Ghera N (2001) Erythropoietin induces tumour progression and antitumour immune responses in murine myeloma models. Proc Natl Acad Sci USA 98: 5181-5186
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5181-5186
    • Mittelman, M.1    Neumann, D.2    Peled, A.3    Kanter, P.4    Haren-Ghera, N.5
  • 35
    • 0037093196 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of recombinant human erythropoietin, epoetin beta, in hematologic malignancies
    • Österborg A, Brandberg Y, Molostova V, Iosava G, Abdulkdyrov K, Hedenus M, Messinger D, Epoetin Beta Hematology Study Group (2002) Randomized, double-blind, placebo-controlled trial of recombinant human erythropoietin, epoetin beta, in hematologic malignancies. J Clin Oncol 20: 2486-2494
    • (2002) J Clin Oncol , vol.20 , pp. 2486-2494
    • Österborg, A.1    Brandberg, Y.2    Molostova, V.3    Iosava, G.4    Abdulkdyrov, K.5    Hedenus, M.6    Messinger, D.7
  • 36
    • 0030012115 scopus 로고    scopus 로고
    • Recombinant human erythropoietin in transfusion-dependent anaemic patients with multiple myeloma and non-Hodgkin's lymphoma-a randomized multicenter study
    • Österborg A, Boogaerts MA, Cimino R, Essers U, Holowiecki J, Juliusson G, Jager G, Najmen A, Peest D (1996) Recombinant human erythropoietin in transfusion-dependent anaemic patients with multiple myeloma and non-Hodgkin's lymphoma-a randomized multicenter study. Blood 87:2675-2682
    • (1996) Blood , vol.87 , pp. 2675-2682
    • Österborg, A.1    Boogaerts, M.A.2    Cimino, R.3    Essers, U.4    Holowiecki, J.5    Juliusson, G.6    Jager, G.7    Najmen, A.8    Peest, D.9
  • 37
    • 17644390912 scopus 로고    scopus 로고
    • Impact of epoetin-beta on survival of patients with lymphoproliferative malignancies: A long-term follow up of a large randomized study
    • Österborg A, Brandberg Y, Hedenus M (2005) Impact of epoetin-beta on survival of patients with lymphoproliferative malignancies: a long-term follow up of a large randomized study. Br J Haematol 129: 206-209
    • (2005) Br J Haematol , vol.129 , pp. 206-209
    • Österborg, A.1    Brandberg, Y.2    Hedenus, M.3
  • 38
    • 40549088086 scopus 로고    scopus 로고
    • Randomized study of the importance of novel erythropoiesis stimulating protein (Aranesp) for the effect of radiotherapy in patients with primary squamous cell carcinoma of the head and neck (HNSCC)-the Danish Head and Neck Cancer Group DAHANCA 10
    • Overgaard J, Hoff C, Sand Hansen H, Specht L, Overgaard M, Grau C, Andersen E, Johansen J, Andersen L, Evensen J (2007) Randomized study of the importance of novel erythropoiesis stimulating protein (Aranesp) for the effect of radiotherapy in patients with primary squamous cell carcinoma of the head and neck (HNSCC)-the Danish Head and Neck Cancer Group DAHANCA 10. Eur J Cancer Supplements 5(6): 7
    • (2007) Eur J Cancer Supplements , vol.5 , Issue.6 , pp. 7
    • Overgaard, J.1    Hoff, C.2    Sand Hansen, H.3    Specht, L.4    Overgaard, M.5    Grau, C.6    Andersen, E.7    Johansen, J.8    Andersen, L.9    Evensen, J.10
  • 39
    • 0032100825 scopus 로고    scopus 로고
    • Increased autologous blood donation in rectal cancer by recombinant human erythropoietin (rhEPO)
    • Rau B, Schlag PM, Willeke F, Herforth C, Stephen P, Frake W (1998) Increased autologous blood donation in rectal cancer by recombinant human erythropoietin (rhEPO). Eur J Cancer 34: 992-998
    • (1998) Eur J Cancer , vol.34 , pp. 992-998
    • Rau, B.1    Schlag, P.M.2    Willeke, F.3    Herforth, C.4    Stephen, P.5    Frake, W.6
  • 40
    • 41949140285 scopus 로고    scopus 로고
    • Darbepoetin alpha for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: Results of a phase III, multicenter, randomized, double-blind, placebo-controlled study
    • Smith Jr RE, Aapro MS, Ludwig H, Pintér T, Smakal M, Ciuleanu TE, Chen L, Lillie T, Glaspy JA (2008) Darbepoetin alpha for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: results of a phase III, multicenter, randomized, double-blind, placebo-controlled study. J Clin Oncol 26(7): 1040-1050
    • (2008) J Clin Oncol , vol.26 , Issue.7 , pp. 1040-1050
    • Smith Jr, R.E.1    Aapro, M.S.2    Ludwig, H.3    Pintér, T.4    Smakal, M.5    Ciuleanu, T.E.6    Chen, L.7    Lillie, T.8    Glaspy, J.A.9
  • 41
    • 40549107811 scopus 로고    scopus 로고
    • Effects of anemia correction with epoetin beta in patients receiving radiochemotherapy for advanced cervical cancer
    • Strauss HG, Haensgen G, Dunst J, Hayward CR, Burger HU, Scherhag A, Koelbl H (2008) Effects of anemia correction with epoetin beta in patients receiving radiochemotherapy for advanced cervical cancer. Int J Gynecol Cancer 18(3): 515-524
    • (2008) Int J Gynecol Cancer , vol.18 , Issue.3 , pp. 515-524
    • Strauss, H.G.1    Haensgen, G.2    Dunst, J.3    Hayward, C.R.4    Burger, H.U.5    Scherhag, A.6    Koelbl, H.7
  • 42
  • 44
    • 0035866333 scopus 로고    scopus 로고
    • Erythropoietin restores the anemia-induced reduction in cyclophosphamide cytotoxicity in rat tumors
    • Thews O, Kelleher DK, Vaupel P (2001) Erythropoietin restores the anemia-induced reduction in cyclophosphamide cytotoxicity in rat tumors. Cancer Res 61: 1358-1361
    • (2001) Cancer Res , vol.61 , pp. 1358-1361
    • Thews, O.1    Kelleher, D.K.2    Vaupel, P.3
  • 45
    • 67049114157 scopus 로고    scopus 로고
    • Benefits and harms of erythropoiesis-stimulating agents for anemia related to cancer: A meta-analysis
    • DOI:10.1503/cmaj.090470
    • Tonelli M, Hemmelgarn B, Reiman T, Manns B, Reaume MN, Lloyd A, Wiebe N, Klarenbach S (2009) Benefits and harms of erythropoiesis-stimulating agents for anemia related to cancer: a meta-analysis. CMAJ 180(11): E62-E71. DOI:10.1503/cmaj.090470
    • (2009) CMAJ , vol.180 , Issue.11
    • Tonelli, M.1    Hemmelgarn, B.2    Reiman, T.3    Manns, B.4    Reaume, M.N.5    Lloyd, A.6    Wiebe, N.7    Klarenbach, S.8
  • 47
    • 1642406966 scopus 로고    scopus 로고
    • Erythropoietin to treat anaemia in patients with head and neck cancer [letter]
    • Vaupel P, Mayer A (2004) Erythropoietin to treat anaemia in patients with head and neck cancer [letter]. Lancet 363: 992
    • (2004) Lancet , vol.363 , pp. 992
    • Vaupel, P.1    Mayer, A.2
  • 49
    • 84891931168 scopus 로고    scopus 로고
    • A systematic review and economic evaluation of epoetin alpha, epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment
    • Wilson J, Yao GL, Raftery J, Bohlius J, Brunskill S, Sandercock J, Bayliss S, Moss P, Stanworth S, Hyde C (2007) A systematic review and economic evaluation of epoetin alpha, epoetin beta and darbepoetin alpha in anaemia associated with cancer, especially that attributable to cancer treatment. Health Technol Assess 11: 1-202
    • (2007) Health Technol Assess , vol.11 , pp. 1-202
    • Wilson, J.1    Yao, G.L.2    Raftery, J.3    Bohlius, J.4    Brunskill, S.5    Sandercock, J.6    Bayliss, S.7    Moss, P.8    Stanworth, S.9    Hyde, C.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.