Structural basis for chiral substrate recognition by two 2,3-butanediol dehydrogenases

FEBS Letters

Volumn 584, Issue 1, 2010, Pages 219-223

  Otagiri, Masato ^a   Ui, Sadaharu ^b   Takusagawa, Yuhsuke ^b   Ohtsuki, Takashi ^b   Kurisu, Genji ^c   Kusunoki, Masami ^b  

^a RIKEN   (Japan)

^b UNIVERSITY OF YAMANASHI   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Butanediol dehydrogenase; Chiral recognition; Short chain dehydrogenase reductase family; Stereoisomer; X ray crystallography

Indexed keywords

2,3 BUTANEDIOL DEHYDROGENASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; MOLECULAR RECOGNITION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STEREOSPECIFICITY; STRUCTURE ANALYSIS;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; BREVIBACTERIUM; BUTYLENE GLYCOLS; CATALYTIC DOMAIN; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TRYPTOPHAN;

EID: 71549166006     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.11.068     Document Type: Article

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