Some biological effects of scorpion envenomation in late pregnant rats

Experimental and Toxicologic Pathology

Volumn 61, Issue 6, 2009, Pages 573-580

  Ben Nasr, Hmed ^a   Serria, Hammami ^a   Chaker, Selma ^a   Riadh, Badraoui ^a   Zouheir, Sahnoun ^a   Kamel, Jamoussi ^a   Tarek, Rebai ^a   Khaled, Zeghal ^a  

^a UNIVERSITY OF SFAX   (Tunisia)

Author keywords

Biochemical disturbances; Haemodynamic; Pregnancy; Rat; Scorpion envenomation

Indexed keywords

CREATININE; ESTRADIOL; GLUCOSE; POTASSIUM; PROGESTERONE; SCORPION VENOM; SODIUM; SODIUM CHLORIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENVENOMATION; ESTRADIOL BLOOD LEVEL; FEMALE; FETAL WELL BEING; FETUS; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HYPERTENSION; LIPID PEROXIDATION; LUNG CONGESTION; LUNG EDEMA; MATERNAL PLASMA; MEAN ARTERIAL PRESSURE; NONHUMAN; POTASSIUM BLOOD LEVEL; PROGESTERONE BLOOD LEVEL; RAT; SODIUM BLOOD LEVEL; THIRD TRIMESTER PREGNANCY; TROPHOBLAST; UREA NITROGEN BLOOD LEVEL;

ANIMALS; ESTRADIOL; FEMALE; LIPID PEROXIDATION; PREGNANCY; PREGNANCY COMPLICATIONS; PROGESTERONE; RATS; RATS, WISTAR; SCORPION VENOMS; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

BUTHUS OCCITANUS TUNETANUS; RATTUS; SCORPIONES;

EID: 71549162114     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2008.12.004     Document Type: Article

References (24)

1. Ben Nasr H., Hamami S., Sahnoun Z., Rebaï T., Bouaziz M., Kassis M., et al. Scorpion envenomation symptoms in pregnant women. J Venom Anim Toxins Incl Trop Dis 13 1 (2007) 94-102
2. Ben Nasr H., Hamami S., Mion G., Sahnoun Z., Chouaiekh F., Rabaï T., et al. Effets de L'envenimation par Buthus occitanus tunetanus sur un modèle experimental murin de gestation. C R Biol 330 (2007) 890-896
3. Ben Nasr H, Hammami TS, Chaker S, Sahnoun Z, Rebaï T, Kassis M, et al. In vivo effects of Buthus occitanus tunetanus and Androctonus australis garzoni scorpion venoms on pregnant and non pregnant rats. J Veno Anim Toxins Incl Trop Dis. Future Publication; 2008.
4. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Methods Enzymol 51 (1972) 302-310
5. Doubilet P.M., and Benson C.B. Fetal growth disturbances. Semin Roentgenol 27 4 (1990) 309-316
6. Dousset E., Carrega L., Steinberg J.G., Clot-Faybesse O., Jouirou B., and Sauze N. Evidence of free radical generation occurs during scorpion envenomation. Comp Biochem Physiol (C) 140 (2005) 221-226
7. D'suze G., Moncada S., Gozalez C., Sevcik C., Aguilar V., and Alagon A. Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting. Toxicon 41 (2003) 367-375
8. Girling J.C. Physiology of pregnancy. Anaesth Intens Care Med (2004) 215-218
9. Grover T.R., Parker T.A., Balasubramaniam V., Markham N.E., and Abman S.H. Pulmonary hypertension impairs alveolarization and reduces lung growth in the ovine fetus. Am J Physiol Lung Cell Mol Physiol 288 (2005) L648-L654
10. Gueron M., and Sofer S. Cardiac dysfunction and pulmonary edema following scorpion envenomation. Chest 102 (1992) 1307-1309
11. 562. Leuk Res 31 (2007) 817-825
12. 125I labelled venom from the scorpion Androctonus amoreuxi (Aud. & Sav). Toxicon 18 3 (1980) 301-308
13. Ismail M., Ellison A.C., and Tilmisany A.K. Teratogenicity in the rat of the venom from the scorpion Androctonus amoreuxi. Toxicon 21 2 (1983) 177-189
14. Karnad D.R. Haemodynamic patterns in patients with scorpion envenomation. Heart 79 (1998) 485-489
15. Krif M.N., Miled K., Abderrazek M., and ElAyeb M. Effects of antivenom on Buthus occitanus tunetanus (Bot) scorpion venom pharmacokinetics: towards an optimization of antivenom immunotherapy in a rabbit model. Toxicon 39 (2001) 1317-1326
16. Merei Z.A., and Ibrahim S.A. Stimulation of the rat uterus by the venom from the scorpion Leiurus quinquestriatus. Toxicon 17 (1979) 251-258
17. Miranda F., Kupeyan C., Rochat H., Rochat C., and Lissitzky S. Purification of animal neurotoxins. Isolation and characterization of eleven neurotoxins from the venoms of the scorpions Androctonus australis hector, Buthus occitanus tunetanus and Leiurus quinquestriatus quinquestriatus. Eur J Biochem 16 3 (1970) 514-523
18. Nassar A.Y., Abu-Sinna G., and Rahim S.A. Effect of a bradykinin-potentiating fraction from venom of the Egyptian scorpion Buthus occitanus on the ovaries and endometrium of mice. Toxicon 28 5 (1990) 525-534
19. Rebai T., Tibi M., Hammami S., Sahnoun Z., Keskes L., Bouayed-Abdelmoula N., et al. Hemodynamics and microcirculation in a rat poisoned by scorpion venom. Arch Mal Coeur Vaiss 96 6 (2003) 653-658
20. Sahnoun Z., Chaker-Krichen S., Kassis M., Hakim A., Hammami S., Ghozzi H., et al. Investigation of the microcirculation and the state of oxidative stress in the rat after scorpion envenomation. Clin Exp Pharmacol Physiol 34 4 (2007) 263-268
21. Simmons R.A. Developmental origin of diabetes: the role of oxidative stress. Free Radical Biol Med 40 (2006) 917-922
22. Xu D.X., Chen Y.H., Zhao L., Wang H., and Wei W. Reactive oxygen species are involved in lipopolysaccharide induced intrauterine growth restriction and skeletal development retardation. Am J Obstet Gynecol 195 (2006) 1707-1714
23. Yuan B., Ohyama K., Bessho T., Uchide N., and Toyoda H. Imbalance between ROS production and elimination results in apoptosis induction in primary smooth chorion trophoblast cells prepared from human fetal membrane tissues. Life Sci 82 (2008) 623-630
24. Zeghal K., Sahnoun Z., Guinot M., Richer C., and Giudicelli J.F. Characterization and mechanisms of the cardiovascular and haemodynamic alterations induced by scorpion venom in rats. Fundam Clin Pharmacol 14 4 (2000) 351-361