Effects of orbitofrontal cortex lesions on cocaine self-administration

Neuroscience

Volumn 165, Issue 2, 2010, Pages 313-324

  Grakalic, I ^a   Panlilio, L V ^a   Quiroz, C ^a   Schindler, C W ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

addiction; drug; dysregulation; food; rat; reinstatement

Indexed keywords

COCAINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSOCIATION; BRAIN DAMAGE; COCAINE DEPENDENCE; CONTROLLED STUDY; MALE; NONHUMAN; ORBITAL CORTEX; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD; STIMULUS RESPONSE; VISUAL STIMULATION;

ANIMALS; COCAINE; COCAINE-RELATED DISORDERS; CONDITIONING, OPERANT; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTINCTION, PSYCHOLOGICAL; FEEDING BEHAVIOR; FRONTAL LOBE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SELF ADMINISTRATION; TIME FACTORS;

EID: 71549154352     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.10.051     Document Type: Article

References (32)

1. Ahmed S.H., and Koob G.F. Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function. Psychopharmacology 180 (2005) 473-490
2. Ahmed S.H., and Koob G.F. Transition from moderate to excessive drug intake: change in hedonic set point. Science 282 (1998) 298-300
3. Bolla K.I., Eldreth D.A., London E.D., Kiehl K.A., Mouratidis M., Contoreggi C., Matochik J.A., Kurian V., Cadet J.L., Kimes A.S., Funderburk F.R., and Ernst M. Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task. Neuroimage 19 (2003) 1085-1094
4. Capriles N., Rodaros D., Sorge R.E., and Stewart J. A role for the prefrontal cortex in stress- and cocaine induced reinstatement of cocaine seeking in rats. Psychopharmacology 168 (2003) 66-74
5. Childress A.R., Mozley P.D., McElgin W., Fitzgerald J., Reivich M., and O'Brien C.P. Limbic activation during cue-induced cocaine craving. Am J Psychiatry 156 (1999) 11-18
6. Cools R., Clark L., Owen A.M., and Robbins T.W. Defining the neural mechanisms of probabilistic reversal learning using event-related functional magnetic resonance imaging. J Neurosci 22 (2002) 4563-4567
7. Everitt B.J., Hutcheson D.M., Ersche K.D., Pelloux Y., Dalley J.W., and Robbins T.W. The orbital prefrontal cortex and drug addiction in laboratory animals and humans. Ann N Y Acad Sci 1121 (2007) 576-597
8. Everitt B.J., and Wolf M.E. Psychomotor stimulant addiction: a neural systems perspective. J Neurosci 22 9 (2002) 3312-3320
9. Fuchs R.A., Evans K.A., Parker M.P., and See R.E. Differential involvement of orbitofrontal cortex subregions in conditioned cue-induced and cocaine-primed reinstatement of cocaine seeking in rats. J Neurosci 24 (2004) 6600-6610
10. Gallagher M., McMahan R.W., and Schoenbaum G. Orbitofrontal cortex and representation of incentive value in associative learning. J Neurosci 19 (1999) 6610-6614
11. Hampton A.N., Bossaerts P., and O'Doherty J.P. The role of the ventromedial prefrontal cortex in abstract state-based inference during decision making in humans. J Neurosci 26 32 (2006) 8360-8367
12. Hutcheson D.M., and Everitt B.J. The effects of selective orbitofrontal cortex lesions on the acquisition and performance of cue-controlled cocaine seeking in rats. Ann N Y Acad Sci 1003 (2003) 410-411
13. Jentsch J.D., and Taylor J.R. Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli. Psychopharmacology 146 (1999) 373-390
14. Kantak K.M., Mashhoon Y., Silverman D.N., Janes A.C., and Goodrich C.M. Role of the orbitofrontal cortex and dorsal striatum in regulating the dose-related effects of self-administered cocaine. Behav Brain Res 201 (2009) 128-136
15. London E.D., Ernst M., Grant S., Bonson K., and Weinstein A. Orbitofrontal cortex and human drug abuse: functional imaging. Cereb Cortex 10 (2000) 334-342
16. Mobini S., Body S., Ho M.Y., Bradshaw C.M., Szabadi E., Deakin J.F., and Anderson I.M. Effects of lesions of the orbitofrontal cortex on sensitivity to delayed and probabilistic reinforcement. Psychopharmacology 160 3 (2002) 290-298
17. Panlilio L.V., Katz J.L., Pickens R.W., and Schindler C.W. Variability of drug self-administration in rats. Psychopharmacology 167 (2003) 9-19
18. Panlilio L.V., Thorndike E.B., and Schindler C.W. A stimulus-control account of regulated drug intake in rats. Psychopharmacology 196 (2008) 441-450
19. Panlilio L.V., Thorndike E.B., and Schindler C.W. A stimulus-control account of dysregulated drug intake. Pharmacol Biochem Behav 92 (2009) 439-447
20. Panlilio L.V., Weiss S.J., and Schindler C.W. Cocaine self-administration increased by compounding discriminative stimuli. Psychopharmacology 125 3 (1996) 202-208
21. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates (1997), Academic Press, New York, NY
22. Phillips A.G., Mora F., and Rolls E.T. Intracerebral self-administration of amphetamine by rhesus monkeys. Neurosci Lett 24 (1981) 81-86
23. Porrino L.J., and Lyons D. Orbital and medial prefrontal cortex and psychostimulant abuse: studies in animal models. Cereb Cortex 10 (2000) 326-333
24. Robinson T.E., and Berridge K.C. Addiction. Annu Rev Psychol 54 (2003) 25-53
25. Rolls E.T., Hornak J., Wade D., and McGrath J. Emotion-related learning in patients with social and emotional changes associated with frontal lobe damage. J Neurol Neurosurg Psychiatry 57 (1994) 1518-1524
26. Schoenbaum G., and Roesch M.R. Orbitofrontal cortex, associative learning, and expectancies. Neuron 47 (2005) 633-636
27. Schoenbaum G., Roesch M.R., and Stalnaker T.A. Orbitofrontal cortex, decision-making and drug addiction. Trends Neurosci 29 (2006) 116-124
28. Schoenbaum G., and Shaham Y. The role of orbitofrontal cortex in drug addiction: a review of preclinical studies. Biol Psychiatry 63 (2008) 256-262
29. Tornatzky W., and Miczek K.A. Cocaine self-administration "binges": transition from behavioral and autonomic regulation toward homeostatic dysregulation in rats. Psychopharmacology 148 (2000) 289-298
30. Volkow N.D., and Fowler J.S. Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. Cereb Cortex 10 (2000) 318-325
31. Wang G.J., Volkow N.D., Fowler J.S., Cervany P., Hitzemann R.J., Pappas N.R., Wong C.T., and Felder C. Regional brain metabolic activation during craving elicited by recall of previous drug experiences. Life Sci 64 (1999) 775-784
32. Wheeler R.A., Twining R.C., Jones J.L., Slater J.M., Grigson P.S., and Carelli R.M. Behavioral and electrophysiological indices of negative affect predict cocaine self-administration. Neuron 57 (2008) 774-785