2′-hydroxylation of genistein enhanced antioxidant and antiproliferative activities in MCF-7 human breast cancer cells

Journal of Microbiology and Biotechnology

Volumn 19, Issue 11, 2009, Pages 1348-1354

  Choi, Jung Nam ^a   Kim, Dockyu ^b   Choi, Hyung Kyoon ^c   Yoo, Kyung Mi ^a   Kim, Jiyoung ^a   Lee, Choong Hwan ^a  

^a Konkuk University   (South Korea)

^b Korea Research Institute of Ships and Ocean Engineering   (South Korea)

^c Chung Ang University   (South Korea)

Author keywords

2 hydroxygenistein; Antioxidant activity; Antiproliferation activity; Bioconversion; Genistein; MCF 7 cells

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2' HYDROXYGENISTEIN; 2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); GENISTEIN; ISOFLAVONOID; UNCLASSIFIED DRUG; 2' HYDROXY GENISTEIN; 2'-HYDROXY-GENISTEIN; 2,2' AZINO DI (3 ETHYLBENZOTHIAZOLINE) 6 SULFONIC ACID; 2,2'-AZINO-DI-(3-ETHYLBENZOTHIAZOLINE)-6-SULFONIC ACID; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; ANTINEOPLASTIC AGENT; ANTIOXIDANT; BENZOTHIAZOLE DERIVATIVE; BIPHENYL DERIVATIVE; CYTOCHROME P 450 CYP81E1 (GLYCYRRHIZA ECHINATA); CYTOCHROME P-450 CYP81E1 (GLYCYRRHIZA ECHINATA); CYTOCHROME P450; DRUG DERIVATIVE; PICRIC ACID; SULFONIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BIOTECHNOLOGICAL PROCEDURES; BIOTRANSFORMATION; BREAST CANCER; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOTOXICITY; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; BREAST TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; FEMALE; HYDROXYLATION; PATHOLOGY; PATHOPHYSIOLOGY; SYNTHESIS; TUMOR CELL LINE;

ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; BENZOTHIAZOLES; BIPHENYL COMPOUNDS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENISTEIN; HUMANS; HYDROXYLATION; MAGNETIC RESONANCE SPECTROSCOPY; PICRATES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONIC ACIDS;

EID: 71549151334     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.0903.0114     Document Type: Article

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