Trait Variability of Cancer Cells Quantified by High-Content Automated Microscopy of Single Cells

Methods in Enzymology

Volumn 467, Issue C, 2009, Pages 23-57

  Quaranta, Vito ^a,b   Tyson, Darren R ^a,b   Garbett, Shawn P ^b   Weidow, Brandy ^a,b   Harris, Mark P ^a   Georgescu, Walter ^b,c  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELL; CANCER GROWTH; CANCER RESEARCH; CELL MOTILITY; CELL POPULATION; CELL PROLIFERATION; IMAGE PROCESSING; MICROSCOPY; PRIORITY JOURNAL; REVIEW;

ALGORITHMS; CELL LINE; CELL PROLIFERATION; CELLULAR STRUCTURES; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICROSCOPY, FLUORESCENCE; NEOPLASMS; PHENOTYPE; QUALITY CONTROL; TUMOR MARKERS, BIOLOGICAL;

EID: 71549116711     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0076-6879(09)67002-6     Document Type: Review

References (49)

1. Alexopoulos L.G., Erickson G.R., and Guilak F. A method for quantifying cell size from differential interference contrast images: Validation and application to osmotically stressed chondrocytes. J. Microsc. 205 Pt 2 (2002) 125-135
2. Anderson A.R.A., Hassanein M., Branch K.M., Lu J., Lobdell N.A., Maier J., Basanta D., Weidow B., Reynolds A.B., Quaranta V., Estrada L., and Weaver A.M. Microenvironmental independence associated with tumor progression. Cancer Research (2009) (in press)
3. Bear J.E., Svitkina T.M., Krause M., Schafer D.A., Loureiro J.J., Strasser G.A., Maly I.V., Chaga O.Y., Cooper J.A., Borisy G.G., and Gertler F.B. Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility. Cell 109 4 (2002) 509-521
4. Berg H.C., and Brown D.A. Chemotaxis in Escherichia coli analysed by three-dimensional tracking. Nature 239 (1972) 500-504
5. Brock A., Chang H., and Huang S. Non-genetic heterogeneity-a mutation-independent driving force for the somatic evolution of tumours. Nat. Rev. Genet. 10 5 (2009) 336-342
6. Bryce N.S., Clark E.S., Leysath J.L., Currie J.D., Webb D.J., and Weaver A.M. Cortactin promotes cell motility by enhancing lamellapodial persistence. Curr. Biol. 15 14 (2005) 1276-1285
7. Cai L., Marshall T.W., Uetrecht A.C., Schafer D.A., and Bear J.E. Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge. Cell 128 5 (2007) 915-929
8. Carpenter A.E., Jones T.R., Lamprecht M.R., Clarke C., Kang I.H., Friman O., Guertin D.A., Chang J.H., Lindquist R.A., Moffat J., Golland P., and Sabatini D.M. Cell Profiler: Image analysis software for identifying and quantifying cellular phenotypes. Genome Biol. 7 10 (2006) R100
9. Codling E.A., Plank M.J., and Benhamou S. Random walk models in biology. J. R. Soc. Interface 5 25 (2008) 813-834
10. Dikovskaya D., Schiffmann D., Newton I.P., Oakley A., Kroboth K., Sansom O., Jamieson T.J., Meniel V., Clarke A., and Näthke I.S. Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. J. Cell Biol 176 2 (2007) 183-195
11. Dove A. Screening for content-The evolution of high throughput. Nat. Biotechnol. 21 (2003) 859-864
12. Duffy K.J., and Ford R.M. Turn angle and run time distributions characterize swimming behavior for Pseudomonas putida. J. Bacteriol. 179 4 (1997) 1428-1430
13. Dunn G.A., and Brown A.F. A unified approach to analyzing cell motility. J. Cell Sci. Suppl. 8 (1987) 81-102
14. Eliason S.R. Maximum Likelihood Estimation: Logic and Practice 96 (1993), SAGE Publications, Thousand Oaks, CA
15. Evans J.G., and Matsudaira P. Linking microscopy and high content screening in large-scale biomedical research. Methods Mol. Biol. 356 (2007) 33-38
16. Fraley C., and Raftery AdrianE. Model-based clustering, discriminant analysis, and density estimation. J. Am. Stat. Assoc. 97 (2002) 611-631
17. Friedl P., and Wolf K. Tumour-cell invasion and migration: Diversity and escape mechanisms. Nat. Rev. 3 (2003) 362-374
18. Furth R. Die Brownsche Bewegung bei Berucksichtigung einer Persistenz der Bewegungsrichtung, Mit Anvendunen auf die Bewegung lebender Infusorien. Z. Physik. 2 (1920) 244-256
19. Gautestad A.O., and Mysterud I. Intrinsic scaling complexity in animal dispersion and abundance. Am. Nat. 165 1 (2005) 44-55
20. Goldberg I.G., Allan C., Burel J.M., Creager D., Falconi A., Hochheiser H., Johnston J., Mellen J., Sorger P.K., and Swedlow J.R. The open microscopy (OME) data model and XML file: Open tools for informatics and quantitative analysis in biological imaging. Genome Biol. 6 (2005) R47
21. Gräf R., Rietdorf J., and Zimmermann T. Live cell spinning disk microscopy. Adv. Biochem. Eng. Biotechnol. 95 (2005) 57-75
22. Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 1 (2000) 57-70
23. Harris M.P., Kim E., Weidow B., Wikswo J.P., and Quaranta V. Migration of isogenic cell lines quantified by dynamic multivariate analysis of single-cell motility. Cell Adh. Migr. 2 2 (2008) 127-136
24. Heng H.H., Bremer S.W., Stevens J.B., Ye K.J., Liu G., and Ye C.J. Genetic and epigenetic heterogeneity in cancer: A genome-centric perspective. J. Cell. Physiol. 220 3 (2009) 538-547
25. Hofmann-Wellenhof R., Fink-Puches R., Smolle J., Helige C., Tritthart H.A., and Kerl H. Correlation of melanoma cell motility and invasion in vitro. Melanoma Res. 5 5 (1995) 311-319
26. Jiao X., Katiyar S., Liu M., Mueller S.C., Lisanti M.P., Li A., Pestell T.G., Wu K., Ju X., Li Z., Wagner E.F., Takeya T., Wang C., and Pestell R.G. Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase. Mol. Biol. Cell 19 4 (2008) 1378-1390
27. Keiding N., and Lauritzen S.L. Marginal maximal likelihood estimates and estimation of the offspring mean in a branching process. Scand. J. Stat. 5 (1978) 106-110
28. Kim H.D., Guo T.W., Wu A.P., Wells A., Gertler F.B., and Lauffenburger D.A. Epidermal growth factor-induced enhancement of glioblastoma cell migration in 3D arises from an intrinsic increase in speed but an extrinsic matrix- and proteolysis-dependent increase in persistence. Mol. Biol. Cell 19 (2008) 4249-4259
29. Kipper M.J., Kleinman H.K., and Wang F.W. New method for modeling connective-tissue cell migration: Improved accuracy on motility parameters. Biophys. J. 93 5 (2007) 1797-1808
30. Loo L.H., Wu L.F., and Altshuler S.J. Image-based multivariate profiling of drug responses from single cells. Nat. Methods 4 5 (2007) 445-453
31. Mukherjee D.P., Ray N., and Acton S.T. Level set analysis for leukocyte detection and tracking. IEEE Trans. Image Process. 13 4 (2004) 562-572
32. Perlman Z.E., Slack M.D., Feng Y., Mitchison T.J., Wu L.F., and Altschuler S.J. Multidimensional drug profiling by automated microscopy. Science 306 5699 (2004) 1194-1198
33. Porter I.M., McClelland S.E., Khoudoli G.A., Hunter C.J., Andersen J.S., McAinsh A.D., Blow J.J., and Swedlow J.R. Bod1, a novel kinetochore protein required for chromosome biorientation. J. Cell Biol. 179 2 (2007) 187-197
34. Potdar A.A., Lu J., Jeon J., Weaver A.M., and Cummings P.T. Bimodal analysis of mammary epithelial cell migration in two dimensions. Ann. Biomed. Eng. 37 1 (2009) 230-245
35. Rasband W.S. ImageJ (1997-2006), U.S. National Institutes of Health, Bethesda, MD, USA. http://rsbweb.nih.gov/ij/
36. Ray N., and Acton S.T. Data acceptance for automated leukocyte tracking through segmentation of spatiotemporal images. IEEE Trans. Biomed. Eng. 52 10 (2005) 1702-1712
37. Roeder K., and Wasserman L. Practical Bayesian density estimation using mixtures of normals. J. Am. Stat. Assoc. 92 (1995)
38. Sakaue-Sawano A., Kurokawa H., Morimura T., Hanyu A., Hama H., Osawa H., Kashiwagi S., Fukami K., Miyata T., Miyoshi H., Imamura T., Ogawa M., et al. Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell 132 3 (2008) 487-498
39. Sisken J.E., and Morasca L. Intrapopulation kinetics of the mitotic cycle. Cell Biol. 25 (1965) 179-189
40. Slack M.D., Martinez E.D., Wu L.F., and Altschuler S.J. Characterizing heterogeneous cellular responses to perturbations. Proc. Natl. Acad. Sci. USA 105 49 (2008) 19306-19311
41. Starkuviene V., and Pepperkok R. The potential of high-content high-throughput microscopy in drug discovery. Br. J. Pharmacol. 152 (2007) 62-71
42. Staude R.G., Huggins R.M., Zhang J., Axelrod D.E., and Kimmel M. Estimating clonal heterogeneity and interexperiment variability with the bifurcating autoregressive model for cell lineage data. Math. Biosci. 143 (1997) 103-121
43. Stockholm D., Benchaouir R., Picot J., Rameau P., Neildez T.M.A., Landini G., Laplace-Builhe C., and Paldi A. The origin of phenotypic heterogeneity in a clonal cell population in vitro. PLoS ONE 2 4 (2007) e394
44. Swedlow J.R., Goldberg I., Brauner E., and Sorger P.K. Informatics and quantitative analysis in biological imaging. Science 300 100 (2003) 100-102
45. Swedlow J.R., Goldberg I.G., and Eliceiri K.W. Bioimage informatics for experimental biology. Annu. Rev. Biophys. 38 (2009) 327-346
46. Uhlenbeck G.E., and Ornstein L.S. On the theory of the Brownian motion. Phys. Rev. 36 (1930) 823-841
47. Viswanathan G.M., Buldyrev S.V., Havlin S., da Luz M.G., Raposo E.P., and Stanley H.E. Optimizing the success of random searches. Nature 401 6756 (1999) 911-914
48. Wallin A.E., Salmi A., and Tuma R. Step length measurement-Theory and simultion for tethered bead constant-force single molecule assay. Biophys. J. 93 3 (2007) 795-805
49. Wells A. Cell Motility in Cancer Invasion and Metastasis. Cancer Metastasis-Biology and Treatment Series (2006), Springer