A high-throughput array for mechanical stimulation of adherent biological cells

TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems

Volumn , Issue , 2009, Pages 2370-2373

  Moraes, C ^a,b   Simmons, C A ^a,b   Sun, Y ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Biomaterials; Cell culture; High throughput screening; Mechanical stimulation; PDMS; Tissue engineering

Indexed keywords

ADHERENT CELLS; BIOLOGICAL CELLS; CELLULAR RESPONSE; HIGH-THROUGHPUT; HIGH-THROUGHPUT SCREENING; MECHANICAL FORCE; MECHANICAL STIMULATION; MECHANICAL STRAIN; MICROFABRICATED; MICROFABRICATED ARRAYS; OUT-OF-PLANE; PDMS;

ACTUATORS; BIOLOGICAL MATERIALS; BIOMATERIALS; CELL CULTURE; CELL PROLIFERATION; MICROCHANNELS; MICROFABRICATION; MICROSYSTEMS; PIEZOELECTRIC TRANSDUCERS; SILICONES; STRAIN; THROUGHPUT; TISSUE ENGINEERING;

SOLID-STATE SENSORS;

EID: 71449112913     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/SENSOR.2009.5285449     Document Type: Conference Paper

References (4)

1. R. McBeath, D.M. Pirone, C.M. Nelson, K. Bhadriraju, C.S. Chen, "Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment," Dev. Cell, vol. 6, pp. 483-495, 2004.
2. Gomez-Sjoberg R, Leyrat AA, Pirone DM, Chen CS, Quake SR, "Versatile, fully automated, microfluidic cell culture system," Anal Chem, vol. 15, pp. 8557-8563, 2007
3. W. Tan, D. Scott, D. Belchenko, H.J. Qi, L. Xiao, "Development and evaluation of microdevices for studying anisotropic biaxial cyclic stretch on cells," Biomed. Microdevices, vol. 10, pp. 869-882, 2008.
4. B.H. Jo, L.M. Van Lerberghe, K.M. Motsegood, D.J. Beebe, "Three-dimensional micro-channel fabrication in PDMS elastomer," J. Microelectromech. Syst., vol. 9, pp. 76-81, 2000.