Tissue-mimicking in vitro analysis system to exclusively stimulate single cell and detect its physiological reaction

TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems

Volumn , Issue , 2009, Pages 932-935

  Okonogi, Atsuhito ^a   Terao, Kyohei ^a   Okitsu, Teru ^a,c   Suzuki, Takaaki ^a,d   Kotera, Hidetoshi ^a,b  

^a JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY HOSPITAL   (Japan)

^d KAGAWA UNIVERSITY   (Japan)

Author keywords

Cell array device; Cellular stimulation response phenomena; Fluorescently Visualizing of cell response; Imaging; Single cell stimulation

Indexed keywords

CELL ARRAY; CELL HANDLING; CELL REACTIONS; CELLULAR STIMULATION; CELLULAR STIMULATION-RESPONSE PHENOMENA; IN-VITRO ANALYSIS; PHYSIOLOGICAL REACTIONS; SINGLE CELLS;

ACTUATORS; BLOOD; BLOOD VESSELS; CELLS; MICROSYSTEMS; ORIFICES; PIEZOELECTRIC TRANSDUCERS; SOLID-STATE SENSORS;

CYTOLOGY;

EID: 71449099593     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/SENSOR.2009.5285969     Document Type: Conference Paper

References (5)

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2. Luther, M. J., A. Hauge-Evans, et al., MIN6 beta-cell-beta-cell interactions influence insulin secretory responses to nutrients and non-nutrients. Biochem Biophys Res Commun. 2006. 343(1): 99-104.
3. Takaaki Suzuki, et al." High throughput cell electroporation array fabricated by single-maskinclined UV lithography exposure and oxygen plasma etching" Transducers'07, pp.687-690, 2007
4. Minami, K., M. Yokokura, et al., Normalization of intracellular Ca(2+) induces a glucose-responsive state in glucose-unresponsive beta-cells. J Biol Chem, 2002. 277(28): 25277-82.
5. Yamada, K., M. Saito, et al., A real-time method of imaging glucose uptake in single, living mammalian cells. 2007. Nat Protoc 2(3): 753-62.