Celecoxib prevents tumor growth in an animal model by a COX-2 independent mechanism

Cancer Chemotherapy and Pharmacology

Volumn 65, Issue 2, 2010, Pages 267-276

  Bastos Pereira, Amanda Leite ^a   Lugarini, Daiana ^a   De Oliveira Christoff, Adriana ^a   Ávila, Thiago Vinicius ^a   Teixeira, Simone ^b   Pires, Amanda Do Rocio Andrade ^a   Muscará, Marcelo Nicolás ^b   Cadena, Sílvia Maria Suter Correia ^a   Donatti, Lucélia ^a   Da Silva De Assis, Helena Cristina ^a   Acco, Alexandra ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Apoptosis; Cancer; Celecoxib; Oxidative stress; Rat; Walker 256

Indexed keywords

CATALASE; CELECOXIB; CYCLOOXYGENASE 2; GLUTATHIONE TRANSFERASE; PROSTAGLANDIN E2; PROTEIN BCL XL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER MODEL; CANCER SURVIVAL; CARCINOSARCOMA; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SARCOMA CELL; SURVIVAL RATE; TUMOR VOLUME; WEIGHT GAIN;

ANIMALS; ANTINEOPLASTIC AGENTS; BCL-X PROTEIN; BODY WEIGHT; CATALASE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; FREE RADICAL SCAVENGERS; GLUTATHIONE TRANSFERASE; LIPID PEROXIDATION; MALE; MITOCHONDRIA; NEOPLASMS, EXPERIMENTAL; PYRAZOLES; RATS; RATS, WISTAR; SULFONAMIDES; SUPEROXIDE DISMUTASE; TUMOR BURDEN;

EID: 71349084464     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-009-1031-8     Document Type: Article

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