ATP-dependent stabilization and protection of fibroblast growth factor 2

Journal of Biotechnology

Volumn 145, Issue 1, 2010, Pages 54-59

  Rose, Karsten ^a   Gast, Ronald E ^a   Seeger, Anna ^a   Krieglstein, Josef ^a   Klumpp, Susanne ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

ATP; Complex; Fibroblast growth factor 2; Neutrophile elastase; Plasmin; Protease resistance; Stabilization

Indexed keywords

ALKALINE PHOSPHATASE; ANGIOGENESIS; ATP-BINDING; BONE REGENERATION; CARDIOPROTECTION; CLINICAL TRIAL; COMPLEX; ELASTASE; FIBROBLAST GROWTH FACTOR 2; GROWTH FACTOR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; IN-CELL; IN-VITRO; MOLAR RATIO; NEUROPROTECTION; NUCLEOSIDE TRIPHOSPHATES; PROTEASE DIGESTION; PROTECTIVE EFFECTS; STABILIZING EFFECTS; TRIPHOSPHATE; WOUND HEALING;

ANIMAL CELL CULTURE; BIOACTIVITY; BIOMOLECULES; CELL PROLIFERATION; ENDOTHELIAL CELLS; FIBROBLASTS; MEDICAL APPLICATIONS; PEPTIDES; SODIUM; STABILIZATION;

CELL CULTURE;

ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; FIBROBLAST GROWTH FACTOR 2; LEUKOCYTE ELASTASE; PLASMIN; TRYPSIN;

ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG BINDING; DRUG METABOLISM; DRUG STABILITY; ENDOTHELIUM CELL; ENZYME METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; MUTANT; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; CELLS, CULTURED; ENDOTHELIAL CELLS; FIBRINOLYSIN; FIBROBLAST GROWTH FACTOR 2; HUMANS; LEUKOCYTE ELASTASE; MUTATION; PEPTIDE HYDROLASES; PROTEIN STABILITY; TRYPSIN;

EID: 71349084282     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2009.10.005     Document Type: Article

References (30)

1. Ai S., Cheng X.W., Inoue A., Nakamura K., Okumura K., Iguchi A., Morohara T., and Kuzuya M. Angiogenic activity of bFGF and VEGF suppressed by proteolytic cleavage by neutrophile elastase. Biochem. Biophys. Res. Commun. 364 (2007) 395-401
2. Caldwell M.A., Garcion E., terBorg M.G., He X., and Svendsen C.N. Heparin stabilizes FGF-2 and modulates striatal precursor cell behaviour in response to EGF. Exp. Neurol. 188 (2004) 408-420
3. Coltrine D., Rusnati M., Zoppetti G., Oreste P., Isacchi A., Caccia P., Bergenzoni L., and Presta M. Biochemical bases of the interaction of human basic fibroblast growth factor with glycosaminoglycans. New insights from trypsin digestion studies. Eur. J. Biochem. 214 (1993) 51-58
4. Fujita M., Ishihara M., Shimizu M., Obara K., Ishizuka T., Saito Y., Yura H., Morimoto Y., Takase B., Matsui T., Kikuchi M., and Maehara T. Vascularization in vivo caused by the controlled release of fibroblast growth factor-2 from injectable chitosan/non-anticoagulant heparin hydrogel. Biomaterials 25 (2004) 699-706
5. Guan R., Sun X.L., Hou S., Wu P., and Chaikof E.L. A glycopolymer chaperone for fibroblast growth factor-2. Bioconjug. Chem. 15 (2004) 145-151
6. Guglieri S., Hricovini M., Raman R., Polito L., Torri G., Casu B., Sasisekharan R., and Guerrini M. Minimum FGF2 binding structural requirements of heparin and heparan sulfate oligosaccharides as determined by NMR spectroscopy. Biochemistry 47 (2008) 13862-13869
7. Harmer N.J. Insights into the role of heparin sulphate in fibroblast growth factor signalling. Biochem. Soc. Trans. 34 3 (2006)
8. Ishihara M., Sato M., Hattori H., Saito Y., Yura H., Ono K., Masuoka K., Kikuchi M., Fujikawa K., and Kurita A. Heparin-carrying polystyrene (HCPS)-bound collagen substratum to immobilize heparin-binding growth factors and to enhance cellular growth. J. Biomed. Mater. Res. 56 (2001) 536-544
9. Johnson D.E., Williams L.T., Gritli-Linde A., Lewis P., McMahon A.P., and Linde A. Structural and functional diversity in the FGF receptor multigene family. Adv. Cancer Res. 60 (1993) 1-41
10. Klumpp S., Kriha D., Bechmann G., Maaßen A., Maier S., Pallast S., Hoell P., and Krieglstein J. Phosphorylation of the growth factors bFGF NGF and BDNF: a prerequisite for their biological activity. Neurochem. Int. 48 (2006) 131-137
11. König S., Hasche A., Pallast S., Krieglstein J., and Klumpp S. Detection of ATP-binding to growth factors. J. Am. Soc. Mass Spectrom. 19 (2008) 91-95
12. Lasker M., Bui C.D., Besant P.G., Sugawara K., Thai P., Medzihradszky G., and Turck C.W. Protein histidine phosphorylation: increased stability of thiophosphohistidine. Protein Sci. 8 (1999) 2177-2185
13. Leker R.R., Soldner F., Velasco I., Gavin D.K., Androutsellis-Theotokis A., and McKay R.D. Long-lasting regeneration after ischemia in the cerebral cortex. Stroke 38 (2007) 153-161
14. Masuoka K., Ishihara M., Asazuma T., Hattori H., Matsui T., Takase B., Kanatani Y., Fujita M., Saito Y., Yura H., Fujikawa K., and Nemoto K. The interaction of chitosan with fibroblast growth factor-2 and its protection from inactivation. Biomaterials 26 (2005) 3277-3284
15. Meddahi A., Lemdjabar H., Caruelle J.P., Barritault D., and Hornebeck W. Inhibition by dextran derivatives of FGF-2 plasmin-mediated degradation. Biochimie 77 (1995) 703-706
16. Meddahi A., Lemdjabar H., Caruelle J.P., Barritault D., and Hornebeck W. FGF protection and inhibition of human neutrophile elastase by carboxymethyl benzylamide sulfonate dextran derivatives. Int. J. Biol. Macromol. 18 (1996) 141-145
17. Mi F.L., Shyu S.S., Peng C.K., Wu Y.B., Sung H.W., Wang P.S., and Huang C.C. Fabrication of chondroitin sulphate-chitosan composite artificial extracellular matrix for stabilization of fibroblast growth factor. J. Biomed. Mater. Res. A 76 (2005) 1-15
18. Nesterenkov M.V., Tilley M., and Upton S.J. A simple modification of Blum's silver stain method allows for 30 minutes detection of proteins in polyacrylamide gels. J. Biochem. Biophys. Methods 28 (1994) 239-242
19. Nishida S., Nagamine H., Tanaka Y., and Watanabe G. Protective effect of basic fibroblast growth factor against myocyte death and arrhythmias in myocardinal infarction in rats. Circ. J. 67 (2003) 334-339
20. Nur-E-Kamal A., Ahmed I., Kamal J., Babu A.N., Schindler M., and Meiners S. Covalently attached FGF-2 to three-dimensional polyamide nanofibrillar surfaces demonstrates enhanced biological stability and activity. Mol. Cell. Biochem. 309 (2008) 157-166
21. Ornitz D.M. FGFs, heparin sulphate and FGFRs: complex interactions essential for development. Bioessays 22 (2000) 108-112
22. Picher M., Burch L.H., Hirsh A.J., Spychala J., and Boucher R.C. Ecto 5′-nucleotidase and nonspecific alkaline phosphatase. Two AMP-hydrolyzing ectoenzymes with distinct roles in human airways. J. Biol. Chem. 278 (2003) 13468-13479
23. Rose K., Kriha D., Pallast S., Junker V., Klumpp S., and Krieglstein J. Basic fibroblast growth factor: lysine 134 is essential for its neuroprotective activity. Neurochem. Int. 51 (2007) 25-31
24. Rose K., Pallast S., Klumpp S., and Krieglstein J. ATP-binding on fibroblast growth factor 2 partially overlaps with the heparin binding domain. J. Biochem. 144 (2008) 343-347
25. Saksela O., Moscatelli D., Sommer A., and Riin D. Endothelial cell derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation. J. Cell Biol. 107 (1988) 743-751
26. Siedle B., Hrenn A., and Merford I. Natural compound as inhibitors of human neutrophile elastase. Planta Med. 73 (2007) 401-420
27. Sommer A., and Rifkin D.B. Interaction of heparin with human basic fibroblast growth factor: protection of the angiogenic protein from proteolytic degradation by a glycosaminoglycan. J. Cell. Physiol. 138 (1989) 215-220
28. Tanihara M., Suzuki Y., Yamamoto E., Noguchi A., and Mizushima Y. Sustained release of basic fibroblast growth factor and angiogenesis in a novel covalently crosslinked gel of heparin and alginate. J. Biomed. Mater. Res. 56 (2001) 216-222
29. Temmerman K., Ebert A.D., Müller H.M., Sinning I., Tews I., and Nickel W. A direct role for phosphatidylinositol-4,5-bisphosphate in unconventional secretion of fibroblast growth factor 2. Traffic 9 (2008) 1204-1217
30. Thompson L.D., Pantoliano M.W., and Springer B.A. Energetic characterization of the basic fibroblast growth factor-heparin interaction: identification of the heparin binding domain. Biochemistry 33 (1994) 3831-3840