Angiogenic activity of bFGF and VEGF suppressed by proteolytic cleavage by neutrophil elastase

Biochemical and Biophysical Research Communications

Volumn 364, Issue 2, 2007, Pages 395-401

  Ai, Shingo ^a,c   Cheng, Xian Wu ^b,d   Inoue, Aiko ^a   Nakamura, Kae ^a   Okumura, Kenji ^b   Iguchi, Akihisa ^a   Murohara, Toyoaki ^a   Kuzuya, Masafumi ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Branch of Medicine in Kohjin Hospital   (Japan)

^d YANBIAN UNIVERSITY   (China)

Author keywords

Angiogenesis; bFGF; Degradation; Neutrophil elastase; Sivelestat; VEGF

Indexed keywords

ANGIOGENIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; LEUKOCYTE ELASTASE; SIVELESTAT; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLAMMATION; MOUSE; NEUTROPHIL GRANULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; GLYCINE; HUMANS; LEUKOCYTE ELASTASE; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; SULFONAMIDES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MUS;

EID: 35548979045     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.10.027     Document Type: Article

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