Nucleosome Serum Levels in Acute Hepatic Failure and MARS Treatment

Transplantation Proceedings

Volumn 41, Issue 10, 2009, Pages 4207-4210

  Roth, G A ^a   Lubsczyk, B A ^a   Pilz, J ^a   Faybik, P ^a   Hetz, H ^a   Krenn, C G ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; HEPARIN; PROSTAGLANDIN;

ACUTE DISEASE; ADULT; AGED; ALBUMIN DIALYSIS; ARTICLE; BLOOD LEVEL; CELL DEATH; CHRONIC DISEASE; CLINICAL ARTICLE; DIFFERENTIAL DIAGNOSIS; DISEASE COURSE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LIVER FAILURE; MALE; NUCLEOSOME; PATIENT MONITORING; PRIORITY JOURNAL;

ADULT; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BLOOD COAGULATION DISORDERS; CELL DEATH; CHRONIC DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INTERNATIONAL NORMALIZED RATIO; LIVER FAILURE, ACUTE; MALE; MIDDLE AGED; NUCLEOSOMES; SURVIVAL RATE; SURVIVORS;

EID: 71249163911     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2009.08.073     Document Type: Article

References (22)

1. Polson J., and Lee W.M. AASLD position paper: the management of acute liver failure. Hepatology 41 (2005) 1179
2. Schmidt L.E., Sorensen V.R., Svendsen L.B., et al. Hemodynamic changes during a single treatment with the molecular adsorbents recirculating system in patients with acute-on-chronic liver failure. Liver Transpl 7 (2001) 1034
3. Schmidt L.E., Wang L.P., Hansen B.A., et al. Systemic hemodynamic effects of treatment with the molecular adsorbents recirculating system in patients with hyperacute liver failure: a prospective controlled trial. Liver Transpl 9 (2003) 290
4. Heemann U., Treichel U., Loock J., et al. Albumin dialysis in cirrhosis with superimposed acute liver injury: a prospective, controlled study. Hepatology 36 4 pt 1 (2002) 949
5. Steiner C., Sen S., Stange J., et al. Binding of bilirubin and bromosulphthalein to albumin: implications for understanding the pathophysiology of liver failure and its management. Liver Transpl 10 (2004) 1531
6. Clapperton M., Rolando N., Sandoval L., et al. Neutrophil superoxide and hydrogen peroxide production in patients with acute liver failure. Eur J Clin Invest 27 (1997) 164
7. Rolando N., Wade J., Davalos M., et al. The systemic inflammatory response syndrome in acute liver failure. Hepatology 32 4 pt 1 (2000) 734
8. Antoniades C.G., Berry P.A., Wendon J.A., et al. The importance of immune dysfunction in determining outcome in acute liver failure. J Hepatol 49 (2008) 845
9. Ryo K., Kamogawa Y., Ikeda I., et al. Significance of Fas antigen-mediated apoptosis in human fulminant hepatic failure. Am J Gastroenterol 95 (2000) 2047
10. Holdenrieder S., Stieber P., Bodenmuller H., et al. Nucleosomes in serum as a marker for cell death. Clin Chem Lab Med 39 (2001) 596
11. Roth G., Moser B., Krenn C., et al. Susceptibility to programmed cell death in T-lymphocytes from septic patients: a mechanism for lymphopenia and Th2 predominance. Biochem Biophys Res Commun 308 (2003) 840
12. Stange J., Hassanein T.I., Mehta R., et al. The molecular adsorbents recycling system as a liver support system based on albumin dialysis: a summary of preclinical investigations, prospective, randomized, controlled clinical trial, and clinical experience from 19 centers. Artif Organs 26 (2002) 103
13. Faybik P., Bacher A., Kozek-Langenecker S.A., et al. Molecular adsorbent recirculating system and hemostasis in patients at high risk of bleeding: an observational study. Crit Care 10 (2006) R24
14. Luger K., Mader A.W., Richmond R.K., et al. Crystal structure of the nucleosome core particle at 2.8 Å resolution. Nature 389 (1997) 251
15. Zhang D., Pasternack M.S., Beresford P.J., et al. Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A. J Biol Chem 276 (2001) 3683
16. Mita A., Hashikura Y., Tagawa Y., et al. Expression of Fas ligand by hepatic macrophages in patients with fulminant hepatic failure. Am J Gastroenterol 100 (2005) 2551
17. Tagawa Y., Kakuta S., and Iwakura Y. Involvement of Fas/Fas ligand system-mediated apoptosis in the development of concanavalin A-induced hepatitis. Eur J Immunol 28 (1998) 4105
18. Canbay A., Guicciardi M.E., Higuchi H., et al. Cathepsin B inactivation attenuates hepatic injury and fibrosis during cholestasis. J Clin Invest 112 (2003) 152
19. Hetz H., Hoetzenecker K., Hacker S., et al. Caspase-cleaved cytokeratin 18 and 20 S proteasome in liver degeneration. J Clin Lab Anal 21 (2007) 277
20. Ankersmit H.J., Deicher R., Moser B., et al. Impaired T cell proliferation, increased soluble death-inducing receptors and activation-induced T cell death in patients undergoing haemodialysis. Clin Exp Immunol 125 (2001) 142
21. Ankersmit H.J., Tugulea S., Spanier T., et al. Activation-induced T-cell death and immune dysfunction after implantation of left-ventricular assist device. Lancet 354 (1999) 550
22. Gauthier V.J., Tyler L.N., and Mannik M. Blood clearance kinetics and liver uptake of mononucleosomes in mice. J Immunol 156 (1996) 1151