Quantification of key folate forms in serum using stable-isotope dilution ultra performance liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 1, 2009, Pages 68-75

  Kirsch, Susanne H ^a   Knapp, Jean Pierre ^a   Herrmann, Wolfgang ^a   Obeid, Rima ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

5 Methyltetrahydrofolate; Folate; Folic acid; Homocysteine; Tandem mass spectrometry

Indexed keywords

BIOLOGICAL PATHWAYS; BIOLOGICAL SIGNIFICANCE; FOLATES; FOLIC ACIDS; GENETIC POLYMORPHISMS; HEALTHY SUBJECTS; HOMOCYSTEINES; ISOTOPE DILUTIONS; MIXED MODE; QUANTIFICATION LIMIT; SMALL POPULATION; SOLID-PHASE; STRONG CORRELATION; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UPLC-MS/MS;

BODY FLUIDS; CHROMATOGRAPHIC ANALYSIS; ION EXCHANGE; ISOTOPES; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; ORGANIC ACIDS; POLYMORPHISM;

LIQUID CHROMATOGRAPHY;

5 METHYLTETRAHYDROFOLIC ACID; FOLIC ACID; HOMOCYSTEINE; ISOTOPE;

ACCURACY; ADULT; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; EXERCISE RECOVERY; FEMALE; GENOTYPE; HUMAN; HUMAN EXPERIMENT; INCUBATION TIME; ION EXCHANGE; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY;

5,10-METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ADOLESCENT; ADULT; CARBON ISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FEMALE; FOLIC ACID; HOMOCYSTEINE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TETRAHYDROFOLATES;

EID: 71149119617     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.11.021     Document Type: Article

References (25)

1. Selhub J. J. Nutr. Health Aging 6 (2002) 39
2. Stover P.J. Nutr. Rev. 62 (2004) S3
3. Smithells R.W., Sheppard S., and Schorah C.J. Arch. Dis. Child 51 (1976) 944
4. Herrmann W., Herrmann M., and Obeid R. Curr. Drug Metab. 8 (2007) 17
5. Boushey C.J., Beresford S.A., Omenn G.S., and Motulsky A.G. JAMA 274 (1995) 1049
6. Kelly P., McPartlin J., Goggins M., Weir D.G., and Scott J.M. Am. J. Clin. Nutr. 65 (1997) 1790
7. Pfeiffer C.M., Fazili Z., McCoy L., Zhang M., and Gunter E.W. Clin. Chem. 50 (2004) 423
8. Molloy A.M., Mills J.L., Kirke P.N., Whitehead A.S., Weir D.G., and Scott J.M. Clin. Chem. 44 (1998) 186
9. Lucock M.D., Hartley R., and Smithells R.W. Biomed. Chromatogr. 3 (1989) 58
10. Bagley P.J., and Selhub J. Clin. Chem. 46 (2000) 404
11. Santhosh-Kumar C.R., and Kolhouse J.F. Methods Enzymol. 281 (1997) 26
12. Shane B., Tamura T., and Stokstad E.L. Clin. Chim. Acta 100 (1980) 13
13. Wang Y., Zhang H.Y., Liang Q.L., Yang H.H., Wang Y.M., Liu Q.F., Hu P., Zheng X.Y., Song X.M., Chen G., Zhang T., Wu J.X., and Luo G.A. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 863 (2008) 94
14. Melse-Boonstra A., Verhoef P., West C.E., van Rhijn J.A., van Breemen R.B., Lasaroms J.J., Garbis S.D., Katan M.B., and Kok F.J. Am. J. Clin. Nutr. 84 (2006) 1128
15. Ronaghi M., Uhlen M., and Nyren P. Science 281 (1998) 363, 365
16. Verri A., Focher F., Tettamanti G., and Grazioli V. Clin. Chem. 51 (2005) 1282
17. Bland J.M., and Altman D.G. Lancet 1 (1986) 307
18. Smith D.E., Kok R.M., Teerlink T., Jakobs C., and Smulders Y.M. Clin. Chem. Lab. Med. 44 (2006) 450
19. Jukes T.H. Science 120 (1954) 324
20. Paine-Wilson B., and Chen T.S. J. Food Sci. (1979) 717
21. Chen T.S., and Cooper R.G. J. Food Sci. (1979) 713
22. De Brouwer V., Zhang G.F., Storozhenko S., Straeten D.V., and Lambert W.E. Phytochem. Anal. 18 (2007) 496
23. Bagley P.J., and Selhub J. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 13217
24. Frosst P., Blom H.J., Milos R., Goyette P., Sheppard C.A., Matthews R.G., Boers G.J., denHeijer M., Kluijtmans L.A., van-den Heuvel L.P., et al. Nat. Genet. 10 (1995) 111
25. Hannisdal R., Ueland P.M., and Svardal A. Clin. Chem. 55 (2009) 1147