Simple assay of plasma sevoflurane and its metabolite hexafluoroisopropanol by headspace GC-MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 1, 2009, Pages 45-50

  Bourdeaux, Daniel ^a,b   Sautou Miranda, Valérie ^a,b   Montagner, Agnès ^a   Perbet, Sébastien ^c   Constantin, Jean Michel ^c   Bazin, Jean Etienne ^c   Chopineau, Jean ^a,b  

^a UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c HÔTEL DIEU   (France)

Author keywords

Anesthetic conserving device; Headspace gas chromatography; HFIP; Mass spectroscopy; Pharmacokinetic study; Sevoflurane

Indexed keywords

HEADSPACE GAS CHROMATOGRAPHY; MASS SPECTROSCOPY; PHARMACOKINETIC STUDIES; PHARMACOKINETIC STUDY; SEVOFLURANE;

ANESTHETICS; CARBON DISULFIDE; CHROMATOGRAPHIC ANALYSIS; MASS SPECTROMETERS; MASS SPECTROMETRY; METABOLISM; METABOLITES; ORGANIC SOLVENTS; PHARMACOKINETICS; SOLVENTS; TOXIC MATERIALS;

GAS CHROMATOGRAPHY;

ANESTHETIC AGENT; CARBON DISULFIDE; HEXAFLUORO 2 PROPANOL; SEVOFLURANE;

ACCURACY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; HUMAN; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL;

ANESTHETICS, INHALATION; DRUG STABILITY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; LINEAR MODELS; METHYL ETHERS; PROPANOLS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TEMPERATURE;

EID: 71149112137     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.11.018     Document Type: Article

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