Drop penetration time in heterogeneous powder beds

Chemical Engineering Science

Volumn 64, Issue 24, 2009, Pages 5210-5221

  Nguyen, Thanh ^a   Shen, Wei ^a   Hapgood, Karen ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Drop penetration time; Granulation; Hydrophobic; Morphology; Nucleation; Wetting

Indexed keywords

BINDER DISPERSION; DROP PENETRATION; DROP PENETRATION TIME; DROPLETS IMPACT; DRUG LOADING; FINE PARTICLES; GRANULE PROPERTIES; GRANULE SIZE; HIGH-SHEAR GRANULATOR; HYDROPHOBIC; HYDROPHOBIC COMPONENTS; HYDROPHOBIC DRUG; LOW DEGREE; MECHANICAL FORCE; NUCLEATION EXPERIMENTS; POWDER BED; POWDER MIXTURES; POWDER PROPERTIES; POWDER SURFACE; SALICYLIC ACIDS; SINGLE DROPS; SPRAY FLUX; WET GRANULATION;

BINDERS; COALESCENCE; DROP FORMATION; GRANULATION; HYDROPHOBICITY; MIXTURES; MORPHOLOGY; NUCLEATION; SUGARS; SURFACE ACTIVE AGENTS; WETTING;

PARTICLES (PARTICULATE MATTER);

EID: 71149110330     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2009.08.038     Document Type: Article

References (25)

1. Alderborn G., and Nystrom C. Pharmaceutical Powder Compaction Technology (1996), Marcel Dekker, New York
2. Aulton, M.E., Banks, M., 1979. Influence of the hydrophobicity of the powder mix on fluidised bed granulation. In: International Conference on Powder Technology in Pharmacy. Powder Advisory Centre, Basel, Switzerland.
3. Aussillous P., and Quere D. Properties of liquid marbles. Proceedings of the Royal Society A 462 2067 (2006) 973-999
4. Belohlav Z., Brenkova L., Hanika J., Durdil P., Rapek P., and Tomasek V. Effect of drug active substance particles on wet granulation process. Chemical Engineering Research and Design 85 7 (2007) 974-980
5. Cassie A.B.D. Contact angles. Discussions of the Faraday Society 3 (1948) 11-16
6. Cassie A.B.D., and Baxter S. Wettability of porous surfaces. Transactions of the Faraday Society 40 (1944) 546-551
7. Denesuk M., Smith G.L., Zelinski B.J.J., Kreidl N.J., and Uhlmann D.R. Capillary penetration of liquid droplets into porous materials. Journal of Colloid and Interface Science 158 1 (1993) 114-120
8. Dimond P.F. Using nanotechnologies in biotech and medicine. Drug Discovery Channel 25 (2005)
9. Eshtiaghi, N., Liu, J., Shen, W., Hapgood, K.P., 2009. Liquid marble formation: Spreading coefficients or kinetic energy? Powder Technology 196, 126-132.
10. Farber, L., Hapgood, K.P., Michaels, J.N., 2006. Hydrophobic nucleation in particle agglomeration. World Congress of Particle Technology 5. Orlando Florida.
11. Goczo H., Szabo-Revesz P., Farkas B., Hasznos-Nezdei M., Serwanis S.F., Pintye-Hodi K., Kasa P.J., and Eros I. Development of spherical crystals of acetylsalicylic acid for direct tablet-making. Chemical & Pharmaceutical Bulletin 48 12 (2000) 1877-1881
12. Hapgood K.P., Farber L., and Michaels J.N. Agglomeration of hydrophobic powders via solid spreading nucleation. Powder Technology 188 3 (2009) 10.1016/j.powtec.2008.05.004
13. Hapgood K.P., and Khanmohammadi B. Granulation of hydrophobic powders. Powder Technology 189 2 (2009) 10.1016/j.powtec.2008.04.033
14. Hapgood K.P., Litster J.D., Biggs S.R., and Howes T. Drop penetration into porous powder beds. Journal of Colloid and Interface Science 253 2 (2002) 353-366
15. Hapgood K.P., Litster J.D., and Smith R. Nucleation regime map for liquid bound granules. A.I.Ch.E. Journal 49 2 (2003) 350-361
16. Iida K., Hayakawa Y., Okamoto H., Danjo K., and Leuenberger H. Evaluation of flow properties of dry powder inhalation of salbutamol sulfate with lactose carrier. Chemical & Pharmaceutical Bulletin 49 10 (2001) 1326-1330
17. Jaiyeoba K.T. The granulation of ternary mixtures: the effect of the wettability of the powders. Journal of Pharmacy and Pharmacology 32 6 (1980) 386
18. Lerk C.F., Schoonen A.J.M., and Fell J.T. Contact angles and wetting of pharmaceutical powders. Journal of Pharmaceutical Sciences 65 6 (1976) 843-847
19. Litster J.D., and Ennis B.J. The Science and Engineering of Granulation Processes. Particle Technology Series (2004), P. B. Scarlett, Kluwer Academic Publishers, Dordrecht, The Netherlands
20. Marmur A. The radial capillary. Journal of Colloid and Interface Science 124 1 (1988) 301-308
21. Middleman S. Capillary Penetration Dynamics. Modeling Axisymmetric Flows (1995), Academic Press, New York pp. 211-240
22. Poon J.M.H., Immanuel C.D., Doyle III, and Litster J.D. A three-dimensional population balance model of granulation with a mechanistic representation of the nucleation and aggregation phenomena. Chemical Engineering Science 63 5 (2008) 1315-1329
23. Saffie-Siebert R., Ogden J., and Parry-Billings M. Nanotechnology approaches to solving the problems of poorly water-soluble drugs. Drug Discovery World 6 3 (2005) 71-76
24. Salman A.D., Hounslow M.J., and Seville J.P.K. Chapter 15: granulation process control-production of pharmaceutical granules. The classical batch concept and the problem of scale-up. In: Williams J.C., and Allen T. (Eds). Handbook of Powder Technology (2007), Elsevier, Amsterdam, The Netherlands 11
25. Vonk P., Guillaume C.P.F., Ramaker J.S., Vromans H., and Kossen N.W.F. Growth mechanisms of high-shear pelletisation. International Journal of Pharmaceutics 157 1 (1997) 93-102