Using antimicrobial solution for irrigation in appendicitis to lower surgical site infection rates

American Journal of Surgery

Volumn 198, Issue 6, 2009, Pages 875-880

  Parcells, Jeremy P ^a   Mileski, Joan P ^a   Gnagy, Forrest T ^a   Haragan, Adriane F ^a   Mileski, William J ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Abdominal abscess; Antibiotics; Appendectomy; Irrigation; Perforated appendix; Surgical complication; Surgical site infection; Wound infection

Indexed keywords

IMIPENEM;

ABDOMINAL ABSCESS; ADULT; APPENDECTOMY; APPENDICITIS; ARTICLE; CONTROLLED STUDY; HUMAN; INTESTINE LAVAGE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SURGICAL INFECTION; TREATMENT RESPONSE; WOUND INFECTION;

ABDOMINAL ABSCESS; ADULT; ANTIBIOTIC PROPHYLAXIS; APPENDICITIS; DRUG COMBINATIONS; HUMANS; IMIPENEM; INTRAOPERATIVE CARE; IRRIGATION; RETROSPECTIVE STUDIES; SODIUM BICARBONATE; SODIUM CHLORIDE; SODIUM HYPOCHLORITE; SURGICAL WOUND INFECTION;

EID: 71149096292     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2009.09.002     Document Type: Article

References (17)

1. Bohnen J.M., Solomkin M.D., Dellinger E.P., et al. Guidelines for clinical care: anti-infective agents for intra-abdominal infection. Arch Surg 127 (1992) 83-89
2. Wittmann D.H., Schein M., and Condon R.E. Management of secondary peritonitis. Ann Surg 224 (1996) 10-18
3. Nathens A.B., and Rotstein O.D. Antimicrobial therapy for intraabdominal infection. Am J Surg 172 Suppl 6A (1996) 1-6
4. Lord J.W., Rossi G., and Daliana M. Intraoperative antibiotic wound lavage; an attempt to eliminate postoperative infection in arterial and clean general surgical procedures. Ann Surg 185 (1977) 634-641
5. Yelon J.A., Green J.D., and Evans J.T. Efficacy of an intraperitoneal antibiotic to reduce the incidence of infection in the trauma patient: a prospective, randomized study. J Am Coll Surg 182 (1996) 509-514
6. Lord Jr. J.W., LaRaja R.D., Daliana M., et al. Prophylactic antibiotic wound irrigation in gastric, biliary, and colonic surgery. Am J Surg 145 (1983) 209-212
7. Magann E.F., Dodson M.K., Ray M.A., et al. Preoperative skin preparation and intraoperative pelvic irrigation: impact on post-Cesarean endometritis and wound infection. Obstet Gynecol 81 (1993) 922-925
8. Vogel P., and Lenz J. Treatment of pilonidal sinus with excision and primary suture using a local, resorbable antibiotic carrier. Results of a prospective randomized study. Chirurg 63 (1992) 748-753
9. Rushton N. Applications of local antibiotic therapy. Eur J Surg Suppl 578 (1997) 27-30
10. Roth R.M., Gleckman R.A., Gantz N.M., et al. Antibiotic irrigations, a plea for controlled clinical trials. Pharmacotherapy 5 (1985) 222-227
11. Beatty G.L., Mincks J.R., and Pulaski E.J. Acute appendicitis, tetracycline prophylaxis and wound infection. Antibiotic Med Clin Ther 3 (1956) 392-398
12. Halasz N.A. Wound infection and topical antibiotics: the surgeon's dilemma. Arch Surg 112 (1977) 1240-1244
13. Rickett J.W., and Jackson B.T. Topical ampicillin in the appendectomy wound: report of double-blind trial. BMJ 4 (1969) 206-207
14. Longland C.J., Gray J.G., Lees W., et al. The prevention of infection in appendicectomy wounds. Br J Surg 58 (1971) 117-119
15. Orr J.D. Antibiotic peritoneal lavage in childhood appendicitis. J R Coll Surg Edinb 29 (1984) 307-309
16. Charalambous C.P., Tryfonidis M., Swindell R., et al. When should old therapies be abandoned?. A modern look at old studies on topical ampicillin. J Infect 47 (2003) 203-209
17. Helmer K.S., Robinson E.K., Lally K.P., Vasquez J.C., et al. Standardized patient care guidelines reduce infectious morbidity in appendectomy patients. Am J Surg 183 (2002) 608-613