Mechanistic insights into water activation in SAM hydroxide adenosyltransferase (duf-62)

ChemBioChem

Volumn 10, Issue 15, 2009, Pages 2455-2459

  Deng, Hai ^a,b   McMahon, Stephen A ^a   Eustáquio, Alessandra S ^c   Moore, Bradley S ^c,d   Naismith, James H ^a   O'Hagan, David ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Biosynthesis; Catalysis; Enzyme catalysis; Enzymes

Indexed keywords

ARGININE; ASPARTIC ACID; CARBON; HISTIDINE; HYDROGEN; METHIONINE ADENOSYLTRANSFERASE; NUCLEOPHILE; S ADENOSYLHOMOCYSTEINE; SERINE; THREONINE; WATER;

ACTINOBACTERIA; AMINO ACID COMPOSITION; AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL BOND; CONTROLLED STUDY; CRYSTALLIZATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENETIC CONSERVATION; HYDROGEN BOND; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PYROCOCCUS HORIKOSHII; SALINISPORA ARENICOLA; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS;

CATALYTIC DOMAIN; ENZYME ACTIVATION; METHIONINE ADENOSYLTRANSFERASE; MICROMONOSPORACEAE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PYROCOCCUS HORIKOSHII; S-ADENOSYLMETHIONINE; WATER;

PYROCOCCUS HORIKOSHII;

EID: 71049171266     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200900369     Document Type: Article

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