Norcholanic acids as substrates for recombinant 3β-hydroxysteroid dehydrogenase and progesterone 5β-reductase, enzymes of the 5β-cardenolide biosynthesis

Tetrahedron Letters

Volumn 51, Issue 2, 2010, Pages 367-370

  Schebitz, Pia ^a   Nothdurft, Lars ^a   Hensel, Andreas ^b   Müller Uri, Frieder ^a   Kreis, Wolfgang ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

3 Hydroxysteroid dehydrogenase; Cardenolide biosynthesis; Enzyme catalysis; Norcholanic acid; Progesterone 5 reductase; Short chain dehydrogenase reductase

Indexed keywords

23 NOR 5,20(22)E CHOLADIENIC ACID 3B OL; 3 BETA HYDROXYSTEROID DEHYDROGENASE; 5 BETA CARDENOLIDE; ACID; CARDENOLIDE DERIVATIVE; HYDROXYSTEROID DEHYDROGENASE; PROGESTERONE 5 BETA REDUCTASE; RECOMBINANT ENZYME; STEROID 5BETA REDUCTASE; UNCLASSIFIED DRUG;

ARABIDOPSIS; ARTICLE; BIOSYNTHESIS; DEHYDROGENATION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SUBSTRATE; ENZYME SYNTHESIS; ISOMERIZATION; NONHUMAN; NUCLEOTIDE SEQUENCE; STEREOSPECIFICITY;

ARABIDOPSIS THALIANA; DIGITALIS LANATA;

EID: 71049156278     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.11.029     Document Type: Article

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