Di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate inhibit growth and reduce estradiol levels of antral follicles in vitro

Toxicology and Applied Pharmacology

Volumn 242, Issue 2, 2010, Pages 224-230

  Gupta, Rupesh K ^a   Singh, Jeffery M ^a   Leslie, Tracie C ^a   Meachum, Sharon ^a   Flaws, Jodi A ^a   Yao, Humphrey H C ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Antral follicles; Cell cycle; DEHP; MEHP; Ovary; Phthalates

Indexed keywords

AROMATASE; CYCLIN D2; CYCLIN DEPENDENT KINASE 4; ESTRADIOL; MESSENGER RNA; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ANOVULATION; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; ESTRUS CYCLE; FEMALE; GENE EXPRESSION REGULATION; GROWTH INHIBITION; HORMONE BLOOD LEVEL; HORMONE SUBSTITUTION; HORMONE SYNTHESIS; IN VITRO STUDY; MOUSE; NONHUMAN; OVARY CELL CULTURE; OVARY FOLLICLE DEVELOPMENT; PROTEIN EXPRESSION; SEX HORMONE DETERMINATION;

ANIMALS; BASE SEQUENCE; CELL DIVISION; DIETHYLHEXYL PHTHALATE; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESTRADIOL; FEMALE; MICE; OVARIAN FOLLICLE; POLYMERASE CHAIN REACTION; RNA, MESSENGER;

ANIMALIA; MUS;

EID: 71049151925     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.10.011     Document Type: Article

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