The effects of four weeks of creatine supplementation and high-intensity interval training on cardiorespiratory fitness: A randomized controlled trial

Journal of the International Society of Sports Nutrition

Volumn 6, Issue , 2009, Pages

  Graef, Jennifer L ^a   Smith, Abbie E ^a   Kendall, Kristina L ^a   Fukuda, David H ^a   Moon, Jordan R ^a   Beck, Travis W ^a   Cramer, Joel T ^a   Stout, Jeffrey R ^a  

^a UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 71049146783     PISSN: None     EISSN: 15502783     Source Type: Journal    
DOI: 10.1186/1550-2783-6-18     Document Type: Article

References (56)

1. Coyle EF. Integration of the physiological factors determining endurance performance ability. Exerc Sport Sci Rev 1995, 23(25-63).
2. Hawley JA. Adaptations of skeletal muscle to prolonged, intense endurance training. Clin Exp Pharmacol Physiol 2002, 29(3):218-22. 10.1046/j.1440-1681.2002.03623.x, 11906487.
3. Holloszy JO, Coyle EF. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J Appl Physiol 1984, 56(4):831-8.
4. Burgomaster KA, Hughes SC, Heigenhauser GJ, Bradwell SN, Gibala MJ. Six sessions of sprint interval training increases muscle oxidative potential and cycle endurance capacity in humans. J Appl Physiol 2005, 98(6):1985-90. 10.1152/japplphysiol.01095.2004, 15705728.
5. Harmer AR, McKenna MJ, Sutton JR, Snow RJ, Ruell PA, Booth J, Thompson MW, Mackay NA, Stathis CG, Crameri RM, Carey MF, Eager DM. Skeletal muscle metabolic and ionic adaptations during intense exercise following sprint training in humans. J Appl Physiol 2000, 89(5):1793-803.
6. Burgomaster KA, Heigenhauser GJ, Gibala MJ. Effect of short-term sprint interval training on human skeletal muscle carbohydrate metabolism during exercise and time-trial performance. J Appl Physiol 2006, 100(6):2041-7. 10.1152/japplphysiol.01220.2005, 16469933.
7. Weston AR, Myburgh KH, Lindsay FH, Dennis SC, Noakes TD, Hawley JA. Skeletal muscle buffering capacity and endurance performance after high-intensity interval training by well-trained cyclists. Eur J Appl Physiol Occup Physiol 1997, 75(1):7-13. 10.1007/s004210050119, 9007451.
8. Edge J, Bishop D, Goodman C. The effects of training intensity on muscle buffer capacity in females. Eur J Appl Physiol 2006, 96(1):97-105. 10.1007/s00421-005-0068-6, 16283370.
9. Laursen PB, Shing CM, Peake JM, Coombes JS, Jenkins DG. Influence of high-intensity interval training on adaptations in well-trained cyclists. J Strength Cond Res 2005, 19(3):527-33. 10.1519/15964.1, 16095414.
10. Jenkins DG, Quigley BM. The influence of high-intensity exercise training on the Wlim-Tlim relationship. Med Sci Sports Exerc 1993, 25(2):275-82.
11. Helgerud J, Hoydal K, Wang E, Karlsen T, Berg P, Bjerkaas M, Simonsen T, Helgesen C, Hjorth N, Bach R, Hoff J. Aerobic high-intensity intervals improve VO2max more than moderate training. Med Sci Sports Exerc 2007, 39(4):665-71. 10.1249/mss.0b013e3180304570, 17414804.
12. Burke J, Thayer R, Belcamino M. Comparison of effects of two interval-training programmes on lactate and ventilatory thresholds. Br J Sports Med 1994, 28(1):18-21. 10.1136/bjsm.28.1.18, 1332151, 8044486.
13. Cottrell GT, Coast JR, Herb RA. Effect of recovery interval on multiple-bout sprint cycling performance after acute creatine supplementation. J Strength Cond Res 2002, 16(1):109-16. 10.1519/1533-4287(2002)016<0109:EORIOM>2.0.CO;2, 11834115.
14. Bogdanis GC, Nevill ME, Boobis LH, Lakomy HK, Nevill AM. Recovery of power output and muscle metabolites following 30 s of maximal sprint cycling in man. J Physiol 1995, 482(Pt 2):467-80. 1157744, 7714837.
15. Hultman E, Soderlund K, Timmons JA, Cederblad G, Greenhaff PL. Muscle creatine loading in men. J Appl Physiol 1996, 81(1):232-7.
16. Harris RC, Soderlund K, Hultman E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci (Lond) 1992, 83(3):367-74.
17. Stout J, Eckerson J, Ebersole K, Moore G, Perry S, Housh T, Bull A, Cramer J, Batheja A. Effect of creatine loading on neuromuscular fatigue threshold. J Appl Physiol 2000, 88(1):109-12.
18. Volek JS, Kraemer WJ. Creatine Supplementation: Its effect on human muscular performance and body composition. J Strength Cond Res 1996, 10(200-210).
19. Derave W, Eijnde BO, Verbessem P, Ramaekers M, Van Leemputte M, Richter EA, Hespel P. Combined creatine and protein supplementation in conjunction with resistance training promotes muscle GLUT-4 content and glucose tolerance in humans. J Appl Physiol 2003, 94(5):1910-6.
20. Orr GW, Green HJ, Hughson RL, Bennett GW. A computer linear regression model to determine ventilatory anaerobic threshold. J Appl Physiol 1982, 52(5):1349-52.
21. Talanian JL, Galloway SD, Heigenhauser GJ, Bonen A, Spriet LL. Two weeks of high-intensity aerobic interval training increases the capacity for fat oxidation during exercise in women. J Appl Physiol 2007, 102(4):1439-47. 10.1152/japplphysiol.01098.2006, 17170203.
22. Smith AE, Moon JR, Kendall KL, Graef JL, Lockwood CM, Walter AA, Beck TW, Cramer JT, Stout JR. The effects of beta-alanine supplementation and high-intensity interval training on neuromuscular fatigue and muscle function. Eur J Appl Physiol 2009, 105(3):357-63. 10.1007/s00421-008-0911-7, 18989693.
23. Daniels JT, Yarbrough RA, Foster C. Changes in VO2 max and running performance with training. Eur J Appl Physiol Occup Physiol 1978, 39(4):249-54. 10.1007/BF00421448, 710390.
24. Dolgener FA, Brooks WB. The effects of interval and continuous training on VO2 max and performance in the mile run. J Sports Med Phys Fitness 1978, 18(4):345-52.
25. Thomas TR, Adeniran SB, Etheridge GL. Effects of different running programs on VO2 max, percent fat, and plasma lipids. Can J Appl Sport Sci 1984, 9(2):55-62.
26. Westgarth-Taylor C, Hawley JA, Rickard S, Myburgh KH, Noakes TD, Dennis SC. Metabolic and performance adaptations to interval training in endurance-trained cyclists. Eur J Appl Physiol Occup Physiol 1997, 75(4):298-304. 10.1007/s004210050164, 9134360.
27. Burgomaster KA, Howarth KR, Phillips SM, Rakobowchuk M, Macdonald MJ, McGee SL, Gibala MJ. Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans. J Physiol 2008, 586(1):151-60. 10.1113/jphysiol.2007.142109, 2375551, 17991697.
28. Edge J, Bishop D, Goodman C, Dawson B. Effects of high- and moderate-intensity training on metabolism and repeated sprints. Med Sci Sports Exerc 2005, 37(11):1975-82. 10.1249/01.mss.0000175855.35403.4c, 16286869.
29. Gross M, Swensen T, King D. Nonconsecutive- versus consecutive-day high-intensity interval training in cyclists. Med Sci Sports Exerc 2007, 39(9):1666-71. 10.1249/mss.0b013e3180cac209, 17805101.
30. Zoeller RF, Stout JR, O'Kroy JA, Torok DJ, Mielke M. Effects of 28 days of beta-alanine and creatine monohydrate supplementation on aerobic power, ventilatory and lactate thresholds, and time to exhaustion. Amino Acids 2007, 33(3):505-10. 10.1007/s00726-006-0399-6, 16953366.
31. Preen D, Dawson B, Goodman C, Lawrence S, Beilby J, Ching S. Effect of creatine loading on long-term sprint exercise performance and metabolism. Med Sci Sports Exerc 2001, 33(5):814-21.
32. van Loon LJ, Oosterlaar AM, Hartgens F, Hesselink MK, Snow RJ, Wagenmakers AJ. Effects of creatine loading and prolonged creatine supplementation on body composition, fuel selection, sprint and endurance performance in humans. Clin Sci (Lond) 2003, 104(2):153-62. 10.1042/CS20020159, 12546637.
33. McNaughton LR, Dalton B, Tarr J. The effects of creatine supplementation on high-intensity exercise performance in elite performers. Eur J Appl Physiol Occup Physiol 1998, 78(3):236-40. 10.1007/s004210050413, 9721002.
34. MacDougall JD, Hicks AL, MacDonald JR, McKelvie RS, Green HJ, Smith KM. Muscle performance and enzymatic adaptations to sprint interval training. J Appl Physiol 1998, 84(6):2138-42.
35. Hickson RC, Bomze HA, Holloszy JO. Linear increase in aerobic power induced by a strenuous program of endurance exercise. J Appl Physiol 1977, 42(3):372-6.
36. Keith SP, Jacobs I, McLellan TM. Adaptations to training at the individual anaerobic threshold. Eur J Appl Physiol Occup Physiol 1992, 65(4):316-23. 10.1007/BF00868134, 1425631.
37. Rodas G, Ventura JL, Cadefau JA, Cusso R, Parra J. A short training programme for the rapid improvement of both aerobic and anaerobic metabolism. Eur J Appl Physiol 2000, 82(5-6):480-6. 10.1007/s004210000223, 10985604.
38. Tabata I, Nishimura K, Kouzaki M, Hirai Y, Ogita F, Miyachi M, Yamamoto K. Effects of moderate-intensity endurance and high-intensity intermittent training on anaerobic capacity and VO2max. Med Sci Sports Exerc 1996, 28(10):1327-30.
39. Ray CA. Sympathetic adaptations to one-legged training. J Appl Physiol 1999, 86(5):1583-7.
40. Hoogeveen AR. The effect of endurance training on the ventilatory response to exercise in elite cyclists. Eur J Appl Physiol 2000, 82(1-2):45-51. 10.1007/s004210050650, 10879442.
41. Linossier MT, Denis C, Dormois D, Geyssant A, Lacour JR. Ergometric and metabolic adaptation to a 5-s sprint training programme. Eur J Appl Physiol Occup Physiol 1993, 67(5):408-14. 10.1007/BF00376456, 8299612.
42. Nelson AG, Day R, Glickman-Weiss EL, Hegsted M, Kokkonen J, Sampson B. Creatine supplementation alters the response to a graded cycle ergometer test. Eur J Appl Physiol 2000, 83(1):89-94. 10.1007/s004210000244, 11072779.
43. Reardon TF, Ruell PA, Fiatarone Singh MA, Thompson CH, Rooney KB. Creatine supplementation does not enhance submaximal aerobic training adaptations in healthy young men and women. Eur J Appl Physiol 2006, 98(3):234-41. 10.1007/s00421-006-0267-9, 16896727.
44. Murphy AJ, Watsford ML, Coutts AJ, Richards DA. Effects of creatine supplementation on aerobic power and cardiovascular structure and function. J Sci Med Sport 2005, 8(3):305-13. 10.1016/S1440-2440(05)80041-6, 16248471.
45. McConell GK, Shinewell J, Stephens TJ, Stathis CG, Canny BJ, Snow RJ. Creatine supplementation reduces muscle inosine monophosphate during endurance exercise in humans. Med Sci Sports Exerc 2005, 37(12):2054-61. 10.1249/01.mss.0000179096.03129.a4, 16331129.
46. Wasserman K, Beaver WL, Whipp BJ. Gas exchange theory and the lactic acidosis (anaerobic) threshold. Circulation 1990, 81(1 Suppl):II14-30.
47. Wasserman K, Whipp BJ, Koyl SN, Beaver WL. Anaerobic threshold and respiratory gas exchange during exercise. J Appl Physiol 1973, 35(2):236-43.
48. Poole DC, Gaesser GA. Response of ventilatory and lactate thresholds to continuous and interval training. J Appl Physiol 1985, 58(4):1115-21.
49. Acevedo EO, Goldfarb AH. Increased training intensity effects on plasma lactate, ventilatory threshold, and endurance. Med Sci Sports Exerc 1989, 21(5):563-8.
50. Laursen PB, Blanchard MA, Jenkins DG. Acute high-intensity interval training improves Tvent and peak power output in highly trained males. Can J Appl Physiol 2002, 27(4):336-48.
51. Balsom PD, Soderlund K, Sjodin B, Ekblom B. Skeletal muscle metabolism during short duration high-intensity exercise: influence of creatine supplementation. Acta Physiol Scand 1995, 154(3):303-10. 10.1111/j.1748-1716.1995.tb09914.x, 7572228.
52. Febbraio MA, Flanagan TR, Snow RJ, Zhao S, Carey MF. Effect of creatine supplementation on intramuscular TCr, metabolism and performance during intermittent, supramaximal exercise in humans. Acta Physiol Scand 1995, 155(4):387-95. 10.1111/j.1748-1716.1995.tb09988.x, 8719258.
53. Volek JS, Kraemer WJ, Bush JA, Boetes M, Incledon T, Clark KL, Lynch JM. Creatine supplementation enhances muscular performance during high-intensity resistance exercise. J Am Diet Assoc 1997, 97(7):765-70. 10.1016/S0002-8223(97)00189-2, 9216554.
54. Casey A, Constantin-Teodosiu D, Howell S, Hultman E, Greenhaff PL. Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans. Am J Physiol 1996, 271(1 Pt 1):E31-7.
55. Tarnopolsky MA, MacLennan DP. Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females. Int J Sport Nutr Exerc Metab 2000, 10(4):452-63.
56. Jager R, Metzger J, Lautmann K, Shushakov V, Purpura M, Geiss KR, Maassen N. The effects of creatine pyruvate and creatine citrate on performance during high intensity exercise. J Int Soc Sports Nutr 2008, 5(4).