Formulation design and pharmaceutical development of a novel controlled release form of azithromycin for single-dose therapy

Drug Development and Industrial Pharmacy

Volumn 35, Issue 12, 2009, Pages 1522-1529

  Lo, Julian B ^a   Appel, Leah E ^b,c   Herbig, Scott M ^a   McCray, Scott B ^b   Thombre, Avinash G ^a  

^a PFIZER INC   (United States)

^b Bend Research Incorporated   (United States)

^c Green Ridge Consulting   (United States)

Author keywords

Azithromycin; Controlled release; Microspheres; Single dose; Spray congealing

Indexed keywords

AZITHROMYCIN; CALCIUM CARBONATE; MAGNESIUM HYDROXIDE; MICROSPHERE; POLOXAMER; SODIUM DIHYDROGEN PHOSPHATE; TROMETAMOL;

ALKALINIZATION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED RELEASE FORMULATION; DIFFUSION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; HUMAN; MICROENCAPSULATION; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SINGLE DRUG DOSE; STOMACH PH; SUSPENSION; TIME TO MAXIMUM PLASMA CONCENTRATION; X RAY POWDER DIFFRACTION;

ALKALIES; AZITHROMYCIN; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; GASTRIC ACID; GASTRIC ACIDITY DETERMINATION; GASTROINTESTINAL TRACT; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; POLOXAMER; POWDER DIFFRACTION; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; TITRIMETRY;

EID: 71049126998     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639040903037223     Document Type: Article

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