-
1
-
-
16644373473
-
Role of VHL gene mutation in human cancer
-
DOI 10.1200/JCO.2004.05.061
-
Kim 2004 J Clin Oncol 22 4991 10.1200/JCO.2004.05.061 15611513 1:CAS:528:DC%2BD2MXptVWrsw%3D%3D (Pubitemid 46646218)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.24
, pp. 4991-5004
-
-
Kim, W.Y.1
Kaelin, W.G.2
-
4
-
-
48649098245
-
-
10.1016/j.juro.2008.05.015 18635227 1:CAS:528:DC%2BD1cXhtVKmsbvE
-
Choueiri 2008 J Urol 180 860 10.1016/j.juro.2008.05.015 18635227 1:CAS:528:DC%2BD1cXhtVKmsbvE
-
(2008)
J Urol
, vol.180
, pp. 860
-
-
Choueiri1
-
5
-
-
12944266844
-
-
15709180 1:CAS:528:DC%2BD2MXht1ynt7o%3D
-
Lidgren 2005 Clin Cancer Res 11 1129 15709180 1:CAS:528: DC%2BD2MXht1ynt7o%3D
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1129
-
-
Lidgren1
-
6
-
-
55549106466
-
-
10.1200/JCO.2008.18.2170
-
Patel 2008 J Clin Oncol 26 5008 10.1200/JCO.2008.18.2170
-
(2008)
J Clin Oncol
, vol.26
, pp. 5008
-
-
Patel1
-
8
-
-
27144491977
-
Frog skin yields antiviral peptides
-
DOI 10.1038/nm1005-1046, PII N10051046
-
Thomas 2005 Nat Med 11 992 10.1038/nm1005-1046 1:CAS:528: DC%2BD2MXhtVOiurnP (Pubitemid 41486819)
-
(2005)
Nature Medicine
, vol.11
, Issue.10
, pp. 1046
-
-
Thomas, C.1
-
9
-
-
61449137045
-
-
10.1097/PPO.0b013e31819765da
-
Figlin 2009 Cancer 15 7 10.1097/PPO.0b013e31819765da
-
(2009)
Cancer
, vol.15
, pp. 7
-
-
Figlin1
-
10
-
-
0035934596
-
Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon alfa alone in metastatic renal-cell carcinoma: A randomised trial
-
DOI 10.1016/S0140-6736(01)06103-7
-
Mickisch 2001 Lancet 358 966 10.1016/S0140-6736(01)06103-7 11583750 1:CAS:528:DC%2BD3MXntF2qtbw%3D (Pubitemid 32913522)
-
(2001)
Lancet
, vol.358
, Issue.9286
, pp. 966-970
-
-
Mickisch, G.H.J.1
Garin, A.2
Van Poppel, H.3
De Prijck, L.4
Sylvester, R.5
-
11
-
-
0035818877
-
Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer
-
DOI 10.1056/NEJMoa003013
-
Flanigan 2001 N Engl J Med 345 1655 10.1056/NEJMoa003013 11759643 1:CAS:528:DC%2BD3MXovFKjt74%3D (Pubitemid 33126820)
-
(2001)
New England Journal of Medicine
, vol.345
, Issue.23
, pp. 1655-1659
-
-
Flanigan, R.C.1
Salmon, S.E.2
Blumenstein, B.A.3
Bearman, S.I.4
Roy, V.5
McGrath, P.C.6
Caton Jr., J.R.7
Munshi, N.8
Crawford, E.D.9
-
13
-
-
0032772880
-
-
10561319 1:STN:280:DC%2BD3c%2FjtVSnug%3D%3D
-
Motzer 1999 J Clin Oncol 17 2530 10561319 1:STN:280: DC%2BD3c%2FjtVSnug%3D%3D
-
(1999)
J Clin Oncol
, vol.17
, pp. 2530
-
-
Motzer1
-
15
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
DOI 10.1056/NEJMoa066838
-
Hudes 2007 N Engl J Med 356 2271 10.1056/NEJMoa066838 17538086 1:CAS:528:DC%2BD2sXmtVKkurs%3D (Pubitemid 46849157)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
Dutcher, J.4
Figlin, R.5
Kapoor, A.6
Staroslawska, E.7
Sosman, J.8
McDermott, D.9
Bodrogi, I.10
Kovacevic, Z.11
Lesovoy, V.12
Schmidt-Wolf, I.G.H.13
Barbarash, O.14
Gokmen, E.15
O'Toole, T.16
Lustgarten, S.17
Moore, L.18
Motzer, R.J.19
-
16
-
-
33744954585
-
Sunitinib in patients with metastatic renal cell carcinoma
-
DOI 10.1001/jama.295.21.2516
-
Motzer 2006 JAMA 295 2516 10.1001/jama.295.21.2516 16757724 1:CAS:528:DC%2BD28XlsV2rtLk%3D (Pubitemid 43854967)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.21
, pp. 2516-2524
-
-
Motzer, R.J.1
Rini, B.I.2
Bukowski, R.M.3
Curti, B.D.4
George, D.J.5
Hudes, G.R.6
Redman, B.G.7
Margolin, K.A.8
Merchan, J.R.9
Wilding, G.10
Ginsberg, M.S.11
Bacik, J.12
Kim, S.T.13
Baum, C.M.14
Michaelson, M.D.15
-
17
-
-
33644833910
-
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
-
DOI 10.1200/JCO.2005.02.2574
-
Motzer 2006 J Clin Oncol 24 16 10.1200/JCO.2005.02.2574 16330672 1:CAS:528:DC%2BD28Xot1ChtA%3D%3D (Pubitemid 46630489)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.1
, pp. 16-24
-
-
Motzer, R.J.1
Michaelson, M.D.2
Redman, B.G.3
Hudes, G.R.4
Wilding, G.5
Figlin, R.A.6
Ginsberg, M.S.7
Kim, S.T.8
Baum, C.M.9
DePrimo, S.E.10
Li, J.Z.11
Bello, C.L.12
Theuer, C.P.13
George, D.J.14
Rini, B.I.15
-
18
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
DOI 10.1056/NEJMoa065044
-
Motzer 2007 N Engl J Med 356 115 10.1056/NEJMoa065044 17215529 1:CAS:528:DC%2BD2sXksVGqsw%3D%3D (Pubitemid 46089672)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
Michaelson, D.4
Bukowski, R.M.5
Rixe, O.6
Oudard, S.7
Negrier, S.8
Szczylik, C.9
Kim, S.T.10
Chen, I.11
Bycott, P.W.12
Baum, C.M.13
Figlin, R.A.14
-
19
-
-
68949145218
-
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
-
Epub ahead on print
-
Motzer RJ (2009) Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma. J Clin Oncol (Epub ahead on print)
-
(2009)
J Clin Oncol
-
-
Motzer, R.J.1
-
20
-
-
37849001813
-
-
10.1200/JCO.2007.13.3223 18165647 1:CAS:528:DC%2BD1cXhsVCrtr4%3D
-
Choueiri 2008 J Clin Oncol 26 127 10.1200/JCO.2007.13.3223 18165647 1:CAS:528:DC%2BD1cXhsVCrtr4%3D
-
(2008)
J Clin Oncol
, vol.26
, pp. 127
-
-
Choueiri1
-
21
-
-
65249166077
-
-
10.3816/CGC.2009.n.005 19213665 1:CAS:528:DC%2BD1MXjslKqs7k%3D
-
Motzer 2009 Clin Genitourin Cancer 7 28 10.3816/CGC.2009.n.005 19213665 1:CAS:528:DC%2BD1MXjslKqs7k%3D
-
(2009)
Clin Genitourin Cancer
, vol.7
, pp. 28
-
-
Motzer1
-
23
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
DOI 10.1056/NEJMoa060655
-
Escudier 2007 N Engl J Med 356 125 10.1056/NEJMoa060655 17215530 1:CAS:528:DC%2BD2sXksVKitg%3D%3D (Pubitemid 46089673)
-
(2007)
New England Journal of Medicine
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Eisen, T.2
Stadler, W.M.3
Szczylik, C.4
Oudard, S.5
Siebels, M.6
Negrier, S.7
Chevreau, C.8
Solska, E.9
Desai, A.A.10
Rolland, F.11
Demkow, T.12
Hutson, T.E.13
Gore, M.14
Freeman, S.15
Schwartz, B.16
Shan, M.17
Simantov, R.18
Bukowski, R.M.19
-
24
-
-
62449186539
-
-
10.1200/JCO.2008.19.3342 1:CAS:528:DC%2BD1MXktFKhsb8%3D
-
Escudier 2008 J Clin Oncol 27 1280 10.1200/JCO.2008.19.3342 1:CAS:528:DC%2BD1MXktFKhsb8%3D
-
(2008)
J Clin Oncol
, vol.27
, pp. 1280
-
-
Escudier1
-
25
-
-
54049134421
-
-
10.1093/jnci/djn319 18840822 1:CAS:528:DC%2BD1cXht1Oisb7J
-
Eisen 2008 J Natl Cancer Inst 100 1454 10.1093/jnci/djn319 18840822 1:CAS:528:DC%2BD1cXht1Oisb7J
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1454
-
-
Eisen1
-
27
-
-
1542398693
-
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
-
DOI 10.1200/JCO.2004.08.185
-
Atkins 2004 J Clin Oncol 22 909 10.1200/JCO.2004.08.185 14990647 1:CAS:528:DC%2BD2cXpsVKisr0%3D (Pubitemid 41103603)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.5
, pp. 909-918
-
-
Atkins, M.B.1
Hidalgo, M.2
Stadler, W.M.3
Logan, T.F.4
Dutcher, J.P.5
Hudes, G.R.6
Park, Y.7
Liou, S.-H.8
Marshall, B.9
Boni, J.P.10
Dukart, G.11
Sherman, M.L.12
-
28
-
-
67651056360
-
-
10.1007/s12032-009-9177-0 19229667 1:CAS:528:DC%2BD1MXmtVKitr0%3D
-
Dutcher 2009 Med Oncol 26 202 10.1007/s12032-009-9177-0 19229667 1:CAS:528:DC%2BD1MXmtVKitr0%3D
-
(2009)
Med Oncol
, vol.26
, pp. 202
-
-
Dutcher1
-
29
-
-
48649107474
-
-
10.1016/S0140-6736(08)61039-9 18653228 1:CAS:528:DC%2BD1cXps1GmsLY%3D
-
Motzer 2008 Lancet 372 449 10.1016/S0140-6736(08)61039-9 18653228 1:CAS:528:DC%2BD1cXps1GmsLY%3D
-
(2008)
Lancet
, vol.372
, pp. 449
-
-
Motzer1
-
30
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
DOI 10.1056/NEJMoa021491
-
Yang 2003 N Engl J Med 349 427 10.1056/NEJMoa021491 12890841 1:CAS:528:DC%2BD3sXms1Klu7w%3D (Pubitemid 36910021)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.5
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
Hwu, P.4
Schwartzentruber, D.J.5
Topalian, S.L.6
Steinberg, S.M.7
Chen, H.X.8
Rosenberg, S.A.9
-
31
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial
-
DOI 10.1016/S0140-6736(07)61904-7, PII S0140673607619047
-
Escudier 2007 Lancet 370 2103 10.1016/S0140-6736(07)61904-7 18156031 (Pubitemid 350296300)
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
Ravaud, A.4
Bracarda, S.5
Szczylik, C.6
Chevreau, C.7
Filipek, M.8
Melichar, B.9
Bajetta, E.10
Gorbunova, V.11
Bay, J.-O.12
Bodrogi, I.13
Jagiello-Gruszfeld, A.14
Moore, N.15
-
32
-
-
56749161699
-
-
10.1200/JCO.2008.16.9847 18936475 1:CAS:528:DC%2BD1MXhslClsA%3D%3D
-
Rini 2008 J Clin Oncol 26 5422 10.1200/JCO.2008.16.9847 18936475 1:CAS:528:DC%2BD1MXhslClsA%3D%3D
-
(2008)
J Clin Oncol
, vol.26
, pp. 5422
-
-
Rini1
-
33
-
-
48749092867
-
-
10.1093/annonc/mdn161 18408224 1:STN:280:DC%2BD1cvotVKmtQ%3D%3D
-
Melichar 2008 Ann Oncol 19 1470 10.1093/annonc/mdn161 18408224 1:STN:280:DC%2BD1cvotVKmtQ%3D%3D
-
(2008)
Ann Oncol
, vol.19
, pp. 1470
-
-
Melichar1
-
34
-
-
62849094732
-
-
10.1038/ni.1701 19295632 1:CAS:528:DC%2BD1MXjtlyms78%3D
-
Ghoreschi 2009 Nat Immunol 10 356 10.1038/ni.1701 19295632 1:CAS:528:DC%2BD1MXjtlyms78%3D
-
(2009)
Nat Immunol
, vol.10
, pp. 356
-
-
Ghoreschi1
-
35
-
-
55549097827
-
-
10.1200/JCO.2008.18.3137
-
Sosman 2008 J Clin Oncol 26 5011 10.1200/JCO.2008.18.3137
-
(2008)
J Clin Oncol
, vol.26
, pp. 5011
-
-
Sosman1
-
36
-
-
50849108567
-
Phase II study of bevacizumab and everolimus (RAD001) in the treatment of advanced renal cell carcinoma (RCC)
-
May 20 abstr 5010
-
Whorf R, Hainsworth JD, Spigel DR et al (2008) Phase II study of bevacizumab and everolimus (RAD001) in the treatment of advanced renal cell carcinoma (RCC). J Clin Oncol 26:(May 20 suppl; abstr 5010)
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Whorf, R.1
Hainsworth, J.D.2
Spigel, D.R.3
-
37
-
-
70349379206
-
Phase I/II trial of CCI 779 and bevacizumab in advanced renal cell carcinoma (RCC): Safety and activity in RTKI refractory RCC patients
-
abstr 5039
-
Merchan R, Pitot HC, Qin R et al (2009) Phase I/II trial of CCI 779 and bevacizumab in advanced renal cell carcinoma (RCC): Safety and activity in RTKI refractory RCC patients. J Clin Oncol 27(15 s, (suppl; abstr 5039))
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
-
-
Merchan, R.1
Pitot, H.C.2
Qin, R.3
-
38
-
-
55949123335
-
-
10.1200/JCO.2007.15.6331 18838713
-
Schmidinger 2008 J Clin Oncol 26 5204 10.1200/JCO.2007.15.6331 18838713
-
(2008)
J Clin Oncol
, vol.26
, pp. 5204
-
-
Schmidinger1
-
39
-
-
36849023013
-
Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib
-
DOI 10.1016/S0140-6736(07)61865-0, PII S0140673607618650
-
Chu 2007 Lancet 370 2011 10.1016/S0140-6736(07)61865-0 18083403 1:CAS:528:DC%2BD2sXhsVent7bN (Pubitemid 350236338)
-
(2007)
Lancet
, vol.370
, Issue.9604
, pp. 2011-2019
-
-
Chu, T.F.1
Rupnick, M.A.2
Kerkela, R.3
Dallabrida, S.M.4
Zurakowski, D.5
Nguyen, L.6
Woulfe, K.7
Pravda, E.8
Cassiola, F.9
Desai, J.10
George, S.11
Morgan, J.A.12
Harris, D.M.13
Ismail, N.S.14
Chen, J.-H.15
Schoen, F.J.16
Van Den Abbeele, A.D.17
Demetri, G.D.18
Force, T.19
Chen, M.H.20
more..
-
40
-
-
66149121478
-
-
10.1016/S1470-2045(09)70112-3 19482548 1:CAS:528:DC%2BD1MXms12jtbk%3D
-
Hapani 2009 Lancet Oncol 10 559 10.1016/S1470-2045(09)70112-3 19482548 1:CAS:528:DC%2BD1MXms12jtbk%3D
-
(2009)
Lancet Oncol
, vol.10
, pp. 559
-
-
Hapani1
-
41
-
-
41149108218
-
-
10.1016/j.eururo.2007.11.037 18054825 1:CAS:528:DC%2BD1cXns1ejsbc%3D
-
Bhojani 2008 Eur Urol 53 917 10.1016/j.eururo.2007.11.037 18054825 1:CAS:528:DC%2BD1cXns1ejsbc%3D
-
(2008)
Eur Urol
, vol.53
, pp. 917
-
-
Bhojani1
-
43
-
-
71049154727
-
A phase II study of two dosing regimens of GSK 1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in patients (pts) with papillary renal carcinoma (PRC)
-
abstr 5103
-
Srinivasan R, Linehan WM, Vaishampayan U et al (2009) A phase II study of two dosing regimens of GSK 1363089 (GSK089), a dual MET/VEGFR2 inhibitor, in patients (pts) with papillary renal carcinoma (PRC). J Clin Oncol 27:(suppl; abstr 5103)
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
-
-
Srinivasan, R.1
Linehan, W.M.2
Vaishampayan, U.3
-
44
-
-
58249094490
-
-
10.1200/JCO.2008.18.0000 19064974
-
Golshayan 2009 J Clin Oncol 27 235 10.1200/JCO.2008.18.0000 19064974
-
(2009)
J Clin Oncol
, vol.27
, pp. 235
-
-
Golshayan1
|