Reactivity of 6-halopurine analogs with glutathione as a radiotracer for assessing function of multidrug resistance-associated protein 1

Journal of Medicinal Chemistry

Volumn 52, Issue 22, 2009, Pages 7284-7288

  Okamura, Toshimitsu ^a   Kikuchi, Tatsuya ^a   Fukushi, Kiyoshi ^a   Irie, Toshiaki ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

6 BROMO 7 METHYLPURINE C 14; 6 BROMO 9 METHYLPURINE C 14; 6 CHLORO 7 METHYLPURINE C 14; 6 CHLORO 9 METHYLPURINE C 14; 6 FLUORO 7 METHYLPURINE C 14; 6 FLUORO 9 METHYLPURINE C 14; 6 IODO 7 METHYLPURINE C 14; 6 IODO 9 METHYLPURINE C 14; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN 1; PURINE DERIVATIVE; TRACER; UNCLASSIFIED DRUG;

ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; MONKEY; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FUNCTION; RAT; SPECIES DIFFERENCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; BRAIN; DRUG DESIGN; GLUTATHIONE; HUMANS; HYDROPHOBICITY; ISOMERISM; KINETICS; MALE; MICE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BINDING; PURINES; RADIOACTIVE TRACERS; RATS;

EID: 70949101749     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm901332c     Document Type: Article

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