Somatic and reflex development in suckling rats: Effects of mother treatment with ketogenic diet associated with lack of protein

Nutritional Neuroscience

Volumn 12, Issue 6, 2009, Pages 260-266

  Soares, Ana Karla Ferrer ^a   Guerra, Renata G S ^a   De Castro, Mylena Lucena ^a   Amancio Dos Santos, Angela ^a   Guedes, Rubem Carlos Araújo ^a   Cabral Filho, José Eulálio ^a   Costa, José Audísio ^a   Medeiros, Maria Do Carmo ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

Ketogenic diet; Rat; Reflex responses development; Somatic development

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BODY GROWTH; BRAIN MATURATION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DIETARY INTAKE; FEMALE; KETOGENIC DIET; LIPID DIET; MALE; MATERNAL NUTRITION; NONHUMAN; ONTOGENY; PHYSICAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEFICIENCY; PROTEIN MALNUTRITION; PROTEIN RESTRICTION; RAT; REFLEX; SUCKLING;

AGING; ANIMALS; ANIMALS, SUCKLING; BEHAVIOR, ANIMAL; BODY WEIGHTS AND MEASURES; DIET, PROTEIN-RESTRICTED; FEMALE; KETOGENIC DIET; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PREGNANCY; PROTEIN DEFICIENCY; RATS; RATS, WISTAR; REFLEX; WEIGHT GAIN;

RATTUS;

EID: 70849101241     PISSN: 1028415X     EISSN: 14768305     Source Type: Journal    
DOI: 10.1179/147683009X423427     Document Type: Article

References (41)

1. Carlson SE, Carver JD, House SG. High fat diets varying in ratios of polyunsaturated to saturated fatty acid and linoleic to linolenic acid: a comparison of rat neural and red cell membrane phospholipids. J Nutr 1986; 116: 718-725.
2. Arbuckle L, Innis, S. Docosahexaenoic acid in developing brain and retina of piglets fed high or low α-linolenate formula with and without fish oil. Lipids 1992; 27: 89-93.
3. Yonekubo A, Honda S, Okano M et al. Dietary fish oil alters rat milk composition and liver and brain fatty acid composition of fetal and neonatal rats. J Nutr 1993; 123: 1703-1708.
4. Insull W, Hirsch J, James T et al. The fatty acids of human milk. Alterations produced by manipulation of caloric balance and exchange of dietary fats. J Clin Invest 1959; 38: 443-450.
5. MelliesMJ, Ishikawa TT, Gartside PS et al. Effects of varying maternal dietary fatty acids in lactating women and infants. Am J Clin Nutr 1979; 32: 299-303.
6. Brandorff GA. The effect of dietary fat on the fatty acid composition of lipids secreted in rat milk. Lipids 1980; 15: 276-278.
7. Grigor MR, Warren SM. Dietary regulation of mammary lipogenesis in lactating rats. Biochem J 1980; 188: 61-65.
8. Harzer G, Dieterich I, Haug M. Effects of the diet on the composition of human milk. Ann Nutr Metab 1984; 28: 231-239.
9. Wainwright PE. The role of n-3 essential fatty acids in brain and behavioural development: a cross-fostering study in the mouse. Lipids 1991; 26: 37-45.
10. Hori A, Tandon P, Holmes GL et al. Ketogenic diet: effects on expression of kindled seizures and behavior in adult rats. Epilepsia 1997; 38: 750-758.
11. Nordli RD, DeVivo D. The ketogenic diet revisited: back to the future. Epilepsia 1997; 38: 743-749.
12. Swink TD, Vining EPG, Freeman JM. The ketogenic diet. Adv Pediatr 1997; 44: 297-329.
13. Girard J, Duée PH, Ferré P et al. Fatty acid oxidation and ketogenesis during development. Reprod Nutr Dev 1985; 25: 303-319.
14. Smart J, Dobbing J. Vulnerability of developing brain. Effects of early nutritional deprivation on reflex ontogeny and development of behaviour in the rat. Brain Res 1971; 28: 85-95.
15. Yehuda S, Carasso RL. Effects of dietary fats on learning, pain threshold, thermoregulation and motor activity in rats: interaction with the length of feeding period. J Neurosci 1987; 32: 919-925.
16. Barros KM,Manhaes-De-Castro R, Lopes-De-Souza S et al. A regional model (Northeastern Brazil) of induced mal-nutrition delays ontogeny of reflexes and locomotor activity in rats. Nutr Neurosci 2006; 9: 99-104.
17. Fox WM. Reflex-ontogeny and behavioural development of the mouse. Anim Behav 1965; 13: 234-241.
18. Hisatomi K, Niiyama Y. Effects of postnatal undernutrition on the catecholamine and serotonin contents of suckling rat brain. J Nutr Sci Vitaminol 1980; 26: 279-292.
19. Rodriguez-Perez MC, De Vicente-Perez F, Gomez-Jarabo Garcia G. Effects of protein malnutrition and the administration of cortisol on the reflexologic development in rats. Behav Neural Biol 1992; 58: 165-170.
20. Guedes RCA, Andrade AFD, Cabral-Filho JE. Propagation of cortical spreading depression in malnourished rats: facilitatory effect of dietary protein deficiency. Braz J Med Biol Res 1987; 20: 639-642.
21. Rocha De Melo AP, Guedes RCA. Spreading depression is facilitated in adult rats previously submitted to short episodes of malnutrition during the lactation period. Braz J Med Biol Res 1997; 30: 663-669.
22. Reeves PG, Nielsen FH, Fahey Jr G. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc Writing Committee on the reformulation of the AIN -73A rodent diet. Nutrition 1993; 123: 1939-1951.
23. Dobbing J. Vulnerable periods in developing brain. In: Davison AN, Dobbing J. (eds) Applied Neurochemistry. Oxford: Blackwell, 1968; 287-316.
24. Morgane PJ, Miller M, Kemper T et al. The effects of protein malnutrition on the developing nervous system in the rat. Neurosci Biobehav Rev 1978; 2: 137-230.
25. Morgane PJ, Austin-LaFrance RJ, Bronzino J et al. Prenatal malnutrition and development of the brain. Neurosci Biobehav Rev 1993; 17: 91-128.
26. Saste MD, Carver JD, Stockard JE et al. Maternal diet fatty acid composition affects neurodevelopment in rat pups. J Nutr 1998; 128: 740-743.
27. NeuringerM, Anderson GJ, ConnorWE. The essentiality of n-3 fatty acids for the development and function of retina and brain. Annu Rev Nutr 1997; 8: 517-541.
28. Delion S. Chronic dietary α-linolenic acid deficiency alters dopaminergic and serotoninergic neurotransmission in rats. Nutrient requirements and interactions. J Nutr 1994; 124: 2466-2476.
29. Green P, Yavin E. Natural and accelerated docosahexaenoic acid accumulation in the prenatal rat brain. Lipids 1996; 31: 235-238.
30. Ziegler DR, Araujo E, Rotta LN et al. A ketogenic diet increases protein phosphorylation in brain slices of rats. J Nutr 2002; 132: 483-487.
31. Likhodii SS, Musa K, Cunnane SC. Breath acetone as a measure of systemic ketosis assessed in a rat model of the ketogenic diet. Clin Chem 2002; 48: 115-120.
32. Bough KJ, Eagles DA. A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat. Epilepsia 1999; 40: 138-143.
33. Toyomizu M, Mehara K, Kamada T et al. Effects of various fat sources on growth and hepatic mitochondrial function in mice. Comp Biochem Physiol 1992; 101A: 613-618.
34. Bourre JM, Pascal G, Durand G et al. Alterations in the fatty acid composition of rat brain cells (neurons, astrocytes and oligodendrocytes) and subcellular (myelin and synaptosomes) induced by a diet devoid of n-3 fatty acids myelin. J Neurochem 1984; 43: 342-348.
35. Bourre JM, FrançoisM, Youyou A et al. The effects of dietary α-linolenic acid on the composition of nerve membranes, enzymatic activity, amplitude of electrophysiological parameters, resistance to poisons and performance of learning tasks in rats. J Nutr 1989; 119: 1880-1892.
36. Bourre JM, Bonneil M, Clement M et al. Function of dietary polyunsaturated fatty acids in the nervous system. Prostaglandins Leukotriene Essent Fatty Acids 1993; 48: 5-15.
37. Wainwright PE. Do essential fatty acids play a role in brain and behavioral development? Neurosci Biobehav Rev 1992; 16: 193-205.
38. Benedetti PC, Gentili V, Salvati S et al. Effect of fatty acid composition of dietary oil on myelin development in rats. Nutr Rep Int 1987; 35: 361-372.
39. Lutz M, Durand G. Influence of dietary lipids on fatty acid composition of nervous membranes (myelin and synaptosomes) in rat. Nutr Res 1994; 14: 1365-1373.
40. Yehuda S, Rabinovitz S,Mostofsky DI. Nutritional deficiencies in learning and cognition. J Pediatr Gastroenterol Nutr 2006; 43: S22-S25.
41. Paixao ADO, Trindade AS, Dantas AC et al. Impact of two early malnutrition models on renal and neural functions in rats. In: Vesler LW. (ed)Malnutrition in the 21st Century, vol.XIII. Hauppauge, NY: Nova Science, 2007; 239-263.