Construction and characterization of a stable subgenomic replicon system of a Brazilian dengue virus type 3 strain (BR DEN3 290-02)

Journal of Virological Methods

Volumn 163, Issue 1, 2010, Pages 147-152

  Mosimann, Ana Luiza Pamplona ^a   de Borba, Luana ^a   Bordignon, Juliano ^a   Mason, Peter W ^b   Santos, Claudia N Duarte dos ^a  

^a INSTITUTO CARLOS CHAGAS   (Brazil)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Dengue virus serotype 3; Flavivirus; Replicon

Indexed keywords

PLASMID VECTOR; POLYCLONAL ANTIBODY; RIBOZYME; VIRUS DNA; VIRUS PROTEIN;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; BRAZIL; CONTROLLED STUDY; DENGUE VIRUS; FLAVIVIRUS; GENETIC STABILITY; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REPLICON; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; VIRUS ASSEMBLY; VIRUS CELL INTERACTION; VIRUS CHARACTERIZATION; VIRUS DETECTION; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CELL LINE; CULICIDAE; DENGUE; DENGUE VIRUS; GENETIC VECTORS; HUMANS; REPLICON; VIRUS REPLICATION;

DENGUE VIRUS; DENGUE VIRUS GROUP; DENGUE VIRUS TYPE 3; FLAVIVIRUS;

EID: 70849100235     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2009.09.004     Document Type: Article

References (44)

1. Alvarez D.E., De Lella Ezcurra A.L., Fucito S., and Gamarnik A.V. Role of RNA structures present at the 3′UTR of dengue virus on translation, RNA synthesis, and viral replication. Virology 339 2 (2005) 200-212
2. Alvarez D.E., Lodeiro M.F., Ludueña S.J., Pietrasanta L.I., and Gamarnik A.V. Long-range RNA-RNA interactions circularize the dengue virus genome. J. Virol. 79 11 (2005) 6631-6643
3. Barnes W.M. Plasmid detection and sizing in single colony lysates. Science 195 (1977) 393-394
4. Bredenbeek P.J., Kooi E.A., Lindenbach B., Huijkman N., Rice C.M., and Spaan W.J. A stable full-length yellow fever virus cDNA clone and the role of conserved RNA elements in flavivirus replication. J. Gen. Virol. 84 (2003) 1261-1268
5. Chambers T.J., Hahn C.S., Galler R., and Rice C. Flavivirus genome organization, expression, and replication. Annu. Rev. Microbiol. 44 (1990) 649-688
6. Corver J., Lenches E., Smith K., Robinson R.A., Sando T., Strauss E.G., and Strauss J.H. Fine mapping of a cis-acting sequence element in yellow fever virus RNA that is required for RNA replication and cyclization. J. Virol. 77 3 (2003) 2265-2270
7. Dèspres P., Frenkiel M.P., and Deubel V. Differences between cell membrane fusion activities of two dengue type-1 isolates reflect modifications of viral structure. Virology 196 1 (1993) 209-219
8. Gehrke R., Ecker M., Aberle S.W., Allison S.L., Heinz F.X., and Mandl C.W. Incorporation of Tick-borne encephalitis virus replicons into virus-like particles by a packaging cell line. J. Virol. 77 16 (2003) 8924-8933
9. Gentry M.K., Henchal E.A., McCown J.M., Brandt W.E., and Dalrymple J.M. Identification of distinct antigenic determinants on dengue-2 virus using monoclonal antibodies. Am. J. Trop. Med. Hyg. 31 (1982) 548-555
10. Gritsun T.S., and Gould E.A. Development and analysis of a tick-borne encephalitis virus infectious clone using a novel and rapid strategy. J. Virol. Methods 76 (1998) 109-120
11. Halstead S.B., Chow J.S., and Marchette N.J. Immunological enhancement of dengue virus replication. Nat. New Biol. 243 (1973) 24-26
12. Halstead S.B., and O'rourke E.J. Antibody-enhanced dengue virus infection in primate leucocytes. Nature 265 (1977) 739-741
13. Holden K.L., Stein D.A., Pierson T.C., Ahmed A.A., Clyde K., Iversen P.L., and Harris E. Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3′ stem-loop structure. Virology 344 (2006) 439-452
14. Hurrelbrink R.J., Nestorowicz A., and Mcminn P.C. Characterization of infectious Murray Valley encephalitis virus derived from a stably cloned genome-length cDNA. J. Gen. Virol. 80 (1999) 3115-3125
15. Ishikawa T., Widman D.G., Bourne N., Konishi E., and Mason P.W. Construction and evaluation of a chimeric pseudoinfectious virus vaccine to prevent Japanese encephalitis. Virology 26 (2008) 2772-2781
16. Jones C.T., Patkar C.G., and Kuhn R.J. Construction and applications of yellow fever virus replicons. Virology 331 (2005) 247-259
17. Jones M., Davidson A., Hibbert L., Gruenwald P., Schalaak J., Ball S., Foster G.R., and Jacobs M. Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression. J. Virol. 79 9 (2005) 5414-5420
18. Kofler R.M., Aberle J.H., Aberle S.W., Allison S.L., Heinz F.X., and Mandl C.W. Mimicking live flavivirus immunization with a noninfectious RNA vaccine. Proc. Natl. Acad. Sci. U.S.A. 101 17 (2004) 1951-1956
19. Khromykh A., and Westaway E. Subgenomic replicons of the flavivirus Kunjin: construction and applications. J. Virol. 71 2 (1997) 1497-1505
20. Lo M.K., Tilgner M., Bernard K.A., and Shi P. Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3′ untranslated region of West Nile virus by use of a reporting replicon that differentiates between viral translation and RNA replication. J. Virol. 77 18 (2003) 10004-10014
21. Mason P.W., Zugel M.U., Semproni A.R., Fournier M.J., and Mason T.L. The antigenic structure of dengue type 1 virus envelope and NS1 proteins expressed in Escherichia coli. J. Gen. Virol. 71 (1990) 2107-2114
22. Messer W.B., Gubler D.J., Harris E., Sivananthan K., and De Silva A. Emergence and global spread of a dengue serotype 3, subtype III virus. Emerg. Infect. Dis. 9 7 (2003) 800-809
23. Ministério da saúde, 2006. Situação Epidemiológica da Dengue até Dezembro de 2006. Available at: .
24. Ministério da Saúde, 2007. Informe Epidemiológico da Dengue, Janeiro a Dezembro de 2007. Available at: .
25. Ministério da Saúde, 2008a. Informe epidemiológico da dengue Janeiro a Novembro de 2008. Available at: .
26. Ministério da saúde, 2008b. Casos confirmados de FHD, segundo ano de confirmação. Brasil, Grandes Regiões e Unidades Federadas, 1990-1991, 1994-2008. Available at: .
27. Mongkolsapaya J., Dejnirattisai W., Xu X., Vasanawathana S., Tagthawornchaikul N., Chairunsi A., Sawasdivorn S., Duangchinda T., Dong T., Rowland-Jones S., Yenchitsomanus P., Mcmichael A., Malasit P., and Screaton G. Original antigenic sin and apoptosis in the pathogenesis of dengue hemorrhagic fever. Nat. Med. 9 7 (2003) 921-927
28. Ng Y.C., Gu F., Phong W.Y., Chen Y., Lim S.P., Davidson A., and Vasudevan S.G. Construction and characterization of a stable subgenomic dengue virus type 2 replicon system for antiviral compound and siRNA testing. Antiviral Res. 76 3 (2007) 222-231
29. Nogueira R.M.R., Araújo J.M.G., and Schatzmayr H.G. Dengue viruses in Brazil, 1986-2006. Rev. Panam. Salud Publica. 22 5 (2007) 358-363
30. Nogueira M.B., Stella V., Bordignon J., Batista W.C., De Borba L., Silva L.H.P., Hoffmann F.G., Probst C.M., and Santos C.N.D. Evidence for the co-circulation of dengue virus type 3 genotypes III and V in the northern region of Brazil during the 2002-2004 epidemics. Mem. Inst. Oswaldo Cruz. 103 5 (2008) 483-488
31. Pang X., Zhang M., and Dayton A.I. Development of dengue virus type 2 replicons capable of prolonged expression in host cells. BMC Microbiol. 1 (2001) 18
32. Pierro D.J., Salazar M.I., Beaty B.J., and Olson K.E. Infectious clone construction of dengue virus type 2, strain Jamaican 1409, and characterization of a conditional E6 mutation. J. Gen. Virol. 87 (2006) 2263-2268
33. Poersch C.O., Pavoni D.P., Queiroz M.H., De Borba L., Goldenberg S., Dos Santos C.N.D., and Krieger M.A. Dengue virus infections: comparison of methods for diagnosing the acute disease. J. Clin. Virol. 32 (2005) 272-277
34. Rosen L. The emperor's new clothes revisited, or reflections on the pathogenesis of dengue hemorrhagic fever. Am. J. Trop. Med. Hyg. 26 3 (1977) 337-343
35. Rossi S.L., Zhao Q., O'Donnell V.K., and Mason P.W. Adaptation of West Nile virus replicons to cells in culture and use of replicon-bearing cells to probe antiviral action. Virology 331 (2005) 457-470
36. Scholle F., Girard Y.A., Zhao Q., Higgs S., and Mason P.W. trans-packaged West Nile virus-like particles: infectious properties in vitro and in infected mosquito vectors. J. Virol. 78 21 (2004) 11605-11614
37. Shi P., Tilgner M., and Lo M.K. Construction and characterization of subgenomic replicons of New York strain of West Nile virus. Virology 296 (2002) 219-233
38. Silva R.L.A., Silva A.M., Harris E., and Macdonald G.H. Genetic analysis of dengue 3 virus subtype III 5′ and 3′ non-coding regions. Virus Res. 135 (2008) 320-325
39. Suzuki R., De Borba L., Dos Santos C.N., and Mason P.W. Construction of an infectious cDNA clone for a Brazilian prototype strain of dengue virus type 1: characterization of a temperature-sensitive mutation in NS1. Virology 362 2 (2007) 374-383
40. Widman D.G., Ishikawa T., Fayzulin R., Bourne N., and Mason P. Construction and characterization of a second-generation pseudoinfectious West Nile virus vaccine propagated using a new cultivation system. Vaccine 26 (2008) 2762-2771
41. Yamshchikov V.F., Wengler G., Perelygin A.A., Brinton M.A., and Compans R.W. An infectious clone of the West Nile flavivirus. Virology 281 (2001) 294-304
42. Yoshii K., and Holbrook M.R. Sub-genomic replicon and virus-like particles of Omsk hemorrhagic fever virus. Arch. Virol. 154 4 (2009) 573-580
43. Yun S., Kim S., Rice C.M., and Lee Y. Development and application of a reverse genetics system for Japanese encephalitis virus. J. Virol. 77 11 (2003) 6450-6465
44. Yun S., Choi Y., Yu X., Song J., Shin Y., Ju Y., Kim S., and Lee Y. Engineering the Japanese encephalitis virus RNA genome for the expression of foreign genes of various sizes: Implications for packaging capacity and RNA replication efficiency. J. Neurovirol. 13 6 (2007) 522-535