Protocol for the "Michigan Awareness Control Study": A prospective, randomized, controlled trial comparing electronic alerts based on bispectral index monitoring or minimum alveolar concentration for the prevention of intraoperative awareness

BMC Anesthesiology

Volumn 9, Issue , 2009, Pages 7-

  Mashour, George A ^a   Tremper, Kevin K ^a   Avidan, Michael S ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPNOTIC SEDATIVE AGENT; INHALATION ANESTHETIC AGENT;

ADULT; AGE DISTRIBUTION; ARTICLE; AWARENESS; BISPECTRAL INDEX; CLINICAL PROTOCOL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; GENERAL ANESTHESIA; HIGH RISK PATIENT; HOSPITAL INFORMATION SYSTEM; HUMAN; INTRAOPERATIVE AWARENESS; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MICHIGAN AWARENESS CONTROL STUDY; MINIMUM LUNG ALVEOLUS CONCENTRATION; PATIENT MONITORING; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL;

EID: 70749111068     PISSN: None     EISSN: 14712253     Source Type: Journal    
DOI: 10.1186/1471-2253-9-7     Document Type: Article

References (20)

1. Joint Commission on Accreditation of Healthcare Organizations Preventing, and managing the impact of, anesthesia awareness. Jt Comm Perspect 2004, 24:10-11.
2. Sebel PS, Bowdle TA, Ghoneim MM, Rampil IJ, Padilla RE, Gan TJ, Domino KB. The incidence of awareness during anesthesia: a multicenter United States study. Anesth Analg 2004, 99(3):833-839. 10.1213/01.ANE.0000130261.90896.6C, 15333419.
3. Sandin RH, Enlund G, Samuelsson P, Lennmarken C. Awareness during anaesthesia: a prospective case study. Lancet 2000, 355(9205):707-711. 10.1016/S0140-6736(99)11010-9, 10703802.
4. Osterman JE, Kolk BA. Awareness during anesthesia and posttraumatic stress disorder. Gen Hosp Psychiatry 1998, 20(5):274-281. 10.1016/S0163-8343(98)00035-8, 9788027.
5. Samuelsson P, Brudin L, Sandin RH. Late psychological symptoms after awareness among consecutively included surgical patients. Anesthesiology 2007, 106(1):26-32. 10.1097/00000542-200701000-00009, 17197842.
6. Rosow C, Manberg PJ. Bispectral index monitoring. Anesthesiol Clin North America 2001, 19(4):947-966.
7. Mashour GA. Monitoring consciousness: EEG-based measures of anesthetic depth. Seminars in Anesthesia, Perioperative Medicine and Pain 2006, 25:205-210.
8. Glass PS, Bloom M, Kearse L, Rosow C, Sebel P, Manberg P. Bispectral analysis measures sedation and memory effects of propofol, midazolam, isoflurane, and alfentanil in healthy volunteers. Anesthesiology 1997, 86(4):836-847. 10.1097/00000542-199704000-00014, 9105228.
9. Kearse LA, Rosow C, Zaslavsky A, Connors P, Dershwitz M, Denman W. Bispectral analysis of the electroencephalogram predicts conscious processing of information during propofol sedation and hypnosis. Anesthesiology 1998, 88(1):25-34. 10.1097/00000542-199801000-00007, 9447852.
10. Ekman A, Lindholm ML, Lennmarken C, Sandin R. Reduction in the incidence of awareness using BIS monitoring. Acta Anaesthesiol Scand 2004, 48(1):20-26. 10.1111/j.1399-6576.2004.00260.x, 14674969.
11. Myles PS, Leslie K, McNeil J, Forbes A, Chan MT. Bispectral index monitoring to prevent awareness during anaesthesia: the B-Aware randomised controlled trial. Lancet 2004, 363(9423):1757-1763. 10.1016/S0140-6736(04)16300-9, 15172773.
12. Avidan MS, Zhang L, Burnside BA, Finkel KJ, Searleman AC, Selvidge JA, Saager L, Turner MS, Rao S, Bottros M. Anesthesia awareness and the bispectral index. N Engl J Med 2008, 358(11):1097-1108. 10.1056/NEJMoa0707361, 18337600.
13. Brice DD, Hetherington RR, Utting JE. A simple study of awareness and dreaming during anaesthesia. Br J Anaesth 1970, 42(6):535-542. 10.1093/bja/42.6.535, 5423844.
14. Mashour GA, Esaki RK, Tremper KK, Glick DB, O'Connor M, Avidan MS. A novel classification instrument for intraoperative awareness events. Anesth Analg
15. Ghoneim MM, Block R, Haffarnan M, Mathews M. Awareness during anesthesia: risk factors, causes and sequelae: a review of reported cases in the literature. Anesth Analg 2009, 108(2):527-535. 10.1213/ane.0b013e318193c634, 19151283.
16. Nickalls RWD, Mapleson WW. Age-related iso-MAC charts for isoflurane, sevoflurane and desflurane in man. Br J Anaesth 2003, 91(2):170-174. 10.1093/bja/aeg132, 12878613.
17. Dwyer R, Bennett HL, Eger EI, Heilbron D. Effects of isoflurane and nitrous oxide in subanesthetic concentrations on memory and responsiveness in volunteers. Anesthesiology 1992, 77(5):888-898. 10.1097/00000542-199211000-00009, 1443742.
18. Mashour GA, Esaki RK, Vandervest JC, Shanks A, Kheterpal S. A novel electronic algorithm for detecting potentially insufficient anesthesia: implications for the prevention of intraoperative awareness. J Clin Monit Comput 2009, 23:273-277. 10.1007/s10877-009-9193-9, 19669412.
19. Aantaa R, Jaakola ML, Kallio A, Kanto J. Reduction of the minimum alveolar concentration of isoflurane by dexmedetomidine. Anesthesiology 1997, 86(5):1055-1060. 10.1097/00000542-199705000-00008, 9158354.
20. Eger EI. Age, minimum alveolar anesthetic concentration, and minimum alveolar anesthetic concentration-awake. Anesth Analg 2001, 93(4):947-953. 10.1097/00000539-200110000-00029, 11574362.