Construction of an unmarked recombinant BCG expressing a pertussis antigen by auxotrophic complementation: Protection against Bordetella pertussis challenge in neonates

Vaccine

Volumn 27, Issue 52, 2009, Pages 7346-7351

  Nascimento, Ivan P ^a   Dias, Waldely O ^a   Quintilio, Wagner ^a   Hsu, Tsungda ^b   Jacobs Jr , William R ^b   Leite, Luciana C C ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Auxotroph; Complementation; Neonates; Pertussis; Recombinant BCG; Vaccine

Indexed keywords

BACTERIAL ANTIGEN; BCG VACCINE; GAMMA INTERFERON; LYSINE; PERTUSSIS TOXIN; PLASMID VECTOR; RECOMBINANT VACCINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; AUXOTROPHY; BACTERIAL GENE; BORDETELLA PERTUSSIS; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; GENETIC COMPLEMENTATION; IMMUNOGENICITY; IN VIVO STUDY; LYSA GENE; MOUSE; NEWBORN; NONHUMAN; PERTUSSIS; PRIORITY JOURNAL; SPLEEN CELL; VACCINATION;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, BACTERIAL; BORDETELLA PERTUSSIS; CLONING, MOLECULAR; GENETIC VECTORS; IMMUNITY, CELLULAR; INTERFERON-GAMMA; MICE; MYCOBACTERIUM BOVIS; PERTUSSIS TOXIN; PERTUSSIS VACCINE; RECOMBINANT FUSION PROTEINS; TRANSDUCTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA; WHOOPING COUGH;

EID: 70649108720     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.09.043     Document Type: Article

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