Ex vivo diffusion tensor MRI reflects microscopic structural remodeling associated with aging and disease progression in normal and cardiomyopathic Syrian hamsters

NMR in Biomedicine

Volumn 22, Issue 8, 2009, Pages 819-825

  Li, Wen ^a,b   Lu, Ming ^a,b   Banerjee, Suhanti ^a   Zhong, Jia ^a,b   Ye, Allen ^a,b   Molter, Joseph ^b   Yu, Xin ^a,b,c  

^a Case Western Reserve University   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Calcium deposition; Diffusion tensor MRI; Dilated cardiomyopathy; Fibrosis

Indexed keywords

AGE-MATCHED CONTROLS; CALCIUM DEPOSITION; CARDIAC PATIENTS; CELLULAR LEVELS; CONTRAST AGENT; DIFFUSION ANISOTROPY; DIFFUSION TENSOR MAGNETIC RESONANCE IMAGING; DIFFUSION TENSOR MRI; DIFFUSIVITIES; DILATED CARDIOMYOPATHY; DISEASE PROGRESSION; EX-VIVO; EXTRACELLULAR SPACE; HISTOLOGICAL ANALYSIS; NONDESTRUCTIVE CHARACTERIZATION; NONINVASIVE TECHNIQUE; PATHOLOGICAL CONDITIONS; RADIAL DIFFUSIVITY; STRUCTURAL REMODELING; THERAPEUTIC INTERVENTION; X-RAY CT;

CALCIUM; CALCIUM ALLOYS; DIFFUSION; MAGNETIC RESONANCE IMAGING; PIXELS; RESONANCE; THREE DIMENSIONAL;

TENSORS;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANISOTROPY; ARTICLE; CALCIFICATION; COMPUTER ASSISTED TOMOGRAPHY; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DIFFUSION; DIFFUSION TENSOR IMAGING; DISEASE COURSE; EX VIVO STUDY; EXTRACELLULAR SPACE; HISTOPATHOLOGY; IMAGE DISPLAY; IMAGE QUALITY; MICROSCOPIC ANATOMY; NONHUMAN; PRIORITY JOURNAL; SYRIAN HAMSTER; TISSUE LEVEL;

AGING; ANIMALS; ANISOTROPY; CARDIOMYOPATHY, DILATED; CRICETINAE; DIFFUSION MAGNETIC RESONANCE IMAGING; DISEASE PROGRESSION; HEART; HUMANS; MESOCRICETUS; MYOCARDIUM; TOMOGRAPHY, X-RAY COMPUTED; VENTRICULAR REMODELING; WATER;

CRICETINAE; MESOCRICETUS AURATUS;

EID: 70649100117     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1394     Document Type: Article

References (28)

1. Towbin JA, Bowles NE. Dilated cardiomyopathy: a tale of cytoskeletal proteins and beyond. J. Cardiovasc. Electrophysiol. 2006; 17: 919-926.
2. Brooks A, Schinde V, Bateman AC, Gallagher PJ. Interstitial fibrosis in the dilated non-ischaemic myocardium. Heart 2003; 89: 1255-1256. (Pubitemid 37164032)
3. Pugh KG, Wei JY. Clinical implications of physiological changes in the aging heart. Drugs Aging 2001; 18: 263-276. (Pubitemid 32391814)
4. Chimenti C, Kajstura J, Torella D, Urbanek K, Heleniak H, Colussi C, Di MF, Nadal-Ginard B, Frustaci A, Leri A, Maseri A, Anversa P. Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure. Circ. Res. 2003; 93: 604-613.
5. Garrido L, Wedeen VJ, Kwong KK, Spencer UM, Kantor HL. Anisotropy of water diffusion in the myocardium of the rat. Circ. Res. 1994; 74: 789-793.
6. Reese TG, Weisskoff RM, Smith RN, Rosen BR, Dinsmore RE, Wedeen VJ. Imaging myocardial fiber architecture in vivo with magnetic resonance. Magn. Reson. Med. 1995; 34: 786-791.
7. Tseng WY, Wedeen VJ, Reese TG, Smith RN, Halpern EF. Diffusion tensor MRI of myocardial fibers and sheets: correspondence with visible cut-face texture. J. Magn. Reson. Imaging 2003; 17: 31-42.
8. Scollan DF, Holmes A, Winslow R, Forder J. Histological validation of myocardial microstructure obtained from diffusion tensor magnetic resonance imaging. Am. J. Physiol. 1998; 275: H2308-H2318.
9. Hsu EW, Henriquez CS. Myocardial fiber orientation mapping using reduced encoding diffusion tensor imaging. J Cardiovasc. Magn. Reson. 2001; 3: 339-347.
10. Hsu EW, Buckley DL, Bui JD, Blackband SJ, Forder JR. Two-component diffusion tensor MRI of isolated perfused hearts. Magn. Reson. Med. 2001; 45: 1039-1045.
11. Holmes AA, Scollan DF, Winslow RL. Direct histological validation of diffusion tensor MRI in formaldehyde-fixed myocardium. Magn. Reson. Med. 2000; 44: 157-161.
12. Helm PA, Tseng HJ, Younes L, McVeigh ER, Winslow RL. Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure. Magn. Reson. Med. 2005; 54: 850-859.
13. Chen J, Song SK, Liu W, McLean M, Allen JS, Tan J, Wickline SA, Yu X. Remodeling of cardiac fiber structure after infarction in rats quantified with diffusion tensor MRI. Am. J. Physiol. Heart Circ. Physiol. 2003; 285: H946-H954.
14. Chen J, Liu W, Zhang H, Lacy L, Yang X, Song SK, Wickline SA, Yu X. Regional ventricular wall thickening reflects changes in cardiac fiber and sheet structure during contraction: quantification with diffusion tensor MRI. Am. J. Physiol. Heart Circ. Physiol. 2005; 289: H1898-H1907.
15. Hsu EW, Muzikant AL, Matulevicius SA, Penland RC, Henriquez CS. Magnetic resonance myocardial fiber-orientation mapping with direct histological correlation. Am. J. Physiol. 1998; 274: H1627-H1634.
16. Wu EX, Wu Y, Tang H, Wang J, Yang J, Ng MC, Yang ES, Chan CW, Zhu S, Lau CP, Tse HF. Study of myocardial fiber pathway using magnetic resonance diffusion tensor imaging. Magn. Reson. Imaging 2007; 25: 1048-1057.
17. Wu EX, Wu Y, Nicholls JM, Wang J, Liao S, Zhu S, Lau CP, Tse HF. MR diffusion tensor imaging study of postinfarct myocardium structural remodeling in a porcine model. Magn. Reson. Med. 2007; 58: 687-695.
18. Wu MT, Tseng WY, Su MY, Liu CP, Chiou KR, Wedeen VJ, Reese TG, Yang CF. Diffusion tensor magnetic resonance imaging mapping the fiber architecture remodeling in human myocardium after infarction: correlation with viability and wall motion. Circulation 2006; 114: 1036-1045.
19. Strijkers GJ, Bouts A, Blankesteijn WM, Peeters TH, Vilanova A, van Prooijen MC, Sanders HM, Heijman E, Nicolay K. Diffusion tensor imaging of left ventricular remodeling in response to myocardial infarction in the mouse. NMR Biomed. 2009; 22:182-190.
20. Sakamoto A, Ono K, Abe M, Jasmin G, Eki T, Murakami Y, Masaki T, Toyo-oka T, Hanaoka F. Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, delta-sarcoglycan, in hamster: an animal model of disrupted dystrophin-associated glycoprotein complex. Proc. Natl Acad. Sci. U. S. A. 1997; 94: 13873-13878.
21. Song SK, Sun SW, Ramsbottom MJ, Chang C, Russell J, Cross AH. Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. Neuroimage 2002; 17: 1429-1436. (Pubitemid 35333862)
22. Cheema AH, Gilani SH. Cardiac myopathies in neonatal lambs: histological and histochemical studies. Biol. Neonate 1978; 34: 84-91.
23. Lewis JF, Maron BJ. Cardiovascular consequences of the aging process. Cardiovasc. Clin. 1992; 22: 25-34.
24. Olivetti G, Melissari M, Capasso JM, Anversa P. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy. Circ. Res. 1991; 68: 1560-1568.
25. Petrie CJ, Mark PB, Dargie HJ. Cardiomyopathy in Becker muscular dystrophy-does regional fibrosis mimic infarction? J. Cardiovasc. Magn. Reson. 2005; 7: 823-825.
26. Tseng WY, Reese TG, Weisskoff RM, Wedeen VJ. Cardiac diffusion tensor MRI in vivo without strain correction. Magn. Reson. Med. 1999; 42: 393-403.
27. Dou J, Reese TG, Tseng WY, Wedeen VJ. Cardiac diffusion MRI without motion effects. Magn. Reson. Med. 2002; 48: 105-114.
28. Tseng WY, Dou J, Reese TG, Wedeen VJ. Imaging myocardial fiber disarray and intramural strain hypokinesis in hypertrophic cardiomyopathy with MRI. J. Magn. Reson. Imaging 2006; 23: 1-8.