Multilocus analysis in candidate genes ACE, AGT, and AGTR1 and predisposition to peripheral arterial disease: Role of ACE D/-240T haplotype

Journal of Vascular Surgery

Volumn 50, Issue 6, 2009, Pages 1399-1404

  Fatini, Cinzia ^a   Sticchi, Elena ^a,c   Sofi, Francesco ^a   Said, Abdihakim Abdullahi ^a   Pratesi, Giovanni ^b   Pulli, Raffaele ^b   Pratesi, Carlo ^b   Abbate, Rosanna ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b CAREGGI UNIVERSITY HOSPITAL   (Italy)

^c IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; AGE DISTRIBUTION; AGED; ALLELE; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; DOSE RESPONSE; FEMALE; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SEX RATIO;

ADULT; AGED; AGED, 80 AND OVER; ANGIOTENSINOGEN; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; ODDS RATIO; PEPTIDYL-DIPEPTIDASE A; PERIPHERAL VASCULAR DISEASES; PHENOTYPE; POLYMORPHISM, GENETIC; RECEPTOR, ANGIOTENSIN, TYPE 1; RENIN-ANGIOTENSIN SYSTEM; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 70649091125     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jvs.2009.07.075     Document Type: Article

References (35)

1. Criqui M.H., Denenberg J.O., Langer R.D., and Fronek A. The epidemiology of peripheral arterial disease: importance of identifying the population at risk. Vasc Med 2 (1997) 221-226
2. Li R., Nicklas B., Pahor M., Newman A., Sutton-Tyrrell K., Harris T., et al. Polymorphisms of angiotensinogen and angiotensin-converting enzyme associated with lower extremity arterial disease in the Health, Aging and Body Composition study. J Hum Hypertens 21 (2007) 673-682
3. Khandanpour N., Willis G., Meyer F.J., Armon M.P., Loke Y.K., Wright A.J., et al. Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: a case-control study and meta-analysis. J Vasc Surg 49 (2009) 711-718
4. Mazzolai L., and Hayoz D. The renin-angiotensin system and atherosclerosis. Curr Hypertens Rep 8 (2006) 47-53
5. Tsai C.T., Hwang J.J., Ritchie M.D., Moore J.H., Chiang F.T., Lai L.P., et al. Renin-angiotensin system gene polymorphisms and coronary artery disease in a large angiographic cohort: detection of high order gene-gene interaction. Atherosclerosis 195 (2007) 172-180
6. Mollsten A., Stegmayr B., and Wiklund P.G. Genetic polymorphism in the renin-angiotensin system confer increased risk of stroke independently of blood pressure: a nested case-control study. J Hypertens 26 (2008) 1367-1372
7. Basar Y., Salmayenli N., Aksoy M., Seckin S., Aydin M., and Ozkok E. ACE gene polymorphism in peripheral vascular disease. Horm Metab Res 39 (2007) 534-537
8. Renner W., Pabst E., Paulweber B., Malimare L., Igseder B., Wascher T.C., et al. The angiotensin converting-enzyme gene polymorphism and peripheral arterial occlusive disease. Atherosclerosis 165 (2002) 175-178
9. Jeunemaitre X. Genetics of the human renin angiotensin system. J Mol Med 86 (2008) 637-641
10. Ishigami T., Umemura S., Iwamoto T., Tamura K., Hibi K., Yamaguchi S., et al. Molecular variant of angiotensinogen gene is associated with coronary atherosclerosis. Circulation 91 (1995) 951-954
11. Rigat B., Hubert C., Alhenc-Galles F., Cambien F., Corvol P., and Soubrier F. An insertion/deletion polymorphism in the angiotensin-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86 (1990) 1343-1346
12. Hamdi H.K., and Castellon R. A genetic variant of ACE increases cell survival: a new paradigm for biology and disease. Biochem Biophys Res Commun 318 (2004) 187-191
13. Suehiro T., Morita T., Inoue M., Kumon Y., Ikeda Y., and Hashimoto K. Increased amount of the angiotensin-converting enzyme (ACE) mRNA originating from the ACE allele with deletion. Hum Genet 115 (2004) 91-96
14. Fatini C., Abbate R., Pepe G., Battaglini B., Gensini F., Ruggiano G., et al. Searching for a better assessment of the individual coronary risk profile. The role of angiotensin-converting enzyme, angiotensin II type 1 receptor and angiotensinogen gene polymorphisms. Eur Heart J 21 (2000) 633-638
15. Fatini C., Pratesi G., Sofi F., Gensini F., Sticchi E., Lari B., et al. ACE DD genotype: a predisposing factor for abdominal aortic aneurysm. Eur J Vasc Endovasc Surg 29 (2005) 227-232
16. Foy C.A., Rice G.I., Ossei-Gerning N., Mansfield N.W., and Grant P.J. Angiotensin-converting enzyme (ACE) gene polymorphisms in patients characterized by coronary angiography. Hum Genet 100 (1997) 420-425
17. Benetos A., Gautier S., Ricard S., Topouchian J., Asmar R., Poirier O., et al. Influence of angiotensin-converting enzyme ad angiotensin II type 1 receptor gene polymorphisms on aortic stiffness in normotensive and hypertensive patients. Circulation 94 (1996) 698-703
18. Henrion D., Amant C., Benessiano J., Philip I., Plantefeve G., Chatel D., et al. Angiotensin II type 1 receptor gene polymorphism is associated with an increased vascular reactivity in the human mammary artery in vitro. J Vasc Res 35 (1998) 356-362
19. Sofi F., Cesari F., Tu Y., Pratesi G., Pulli R., Pratesi C., et al. Protein Z-dependent protease inhibitor (ZPI) and protein Z in peripheral arterial disease patients. J Thromb Haemost 7 (2009) 731-735
20. Greenland P., Abrams J., Aurigemma G.P., Bond M.G., Clark L.T., Criqui M.H., et al. Prevention Conference V: beyond secondary prevention: identifying the high-risk patient for primary prevention: noninvasive tests of atherosclerotic burden: Writing Group III. Circulation 101 (2000) E16-E22
21. Practice guidelines for primary care physicians: 2003 ESH/ESC hypertension guidelines. ESH/ESC Hypertension Guidelines Committee. Hypertension 21 (2003) 1779-1786
22. Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adult (Adult Treatment Panel III) final report. Circulation 106 (2002) 3143-3421
23. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 26 (2003) S5-S20
24. Fatini C., Sticchi E., Marcucci R., Said A.A., Del Pace S., Verdiani V., et al. ACE insertion/deletion, but not -240A>T polymorphism, modulates the severity in heart failure. J Investig Med 56 (2008) 1004-1010
25. Becker T., Cichon S., Jönson E., and Knapp M. Multiple testing in the context of haplotype analysis revisited: application to case-control data. Ann Hum Genet 69 (2005) 747-756
26. Thompson A.R., Drenos F., Hafez H., and Humphries S.E. Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis. Eur J Vasc Endovasc Surg 35 (2008) 19-30
27. Karagiannis A., Balaska K., Tziomalos K., Gerasimidis T., Karamanos D., Papayeoryiou A., et al. Lack of an association between angiotensin converting enzyme gene polymorphism and peripheral arterial occlusive disease. Vasc Med 9 (2004) 189-192
28. Rosatto N., Pontremoli R., De Ferrari G., and Ravazzolo R. Intron 16 insertion of the angiotensin converting enzyme and transcriptional regulation. Nephrol Dial Transplant 14 (1999) 868-871
29. Baudin B. Polymorphism in angiotensin II receptor genes and hypertension. Exp Physiol 90 (2005) 277-282
30. Xu M.Q., Ye Z., Hu F.B., and He L. Quantitative assessment of the effect of angiotensinogen gene polymorphisms on the risk of coronary heart disease. Circulation 18 (2007) 1356-1366
31. Kostulas K., Brophy V.H., Moraitis K., Manolescu A., Kostulas V., Gretarsdottir S., et al. Genetic profile of ischemic cerebrovascular disease and carotid stenosis. Acta Neurol Scand 118 (2008) 146-152
32. Ahimastos A.A., Dart A.M., Lawler A., Blombery P.A., and Kingwell B.A. Reduced arterial stiffness may contribute to angiotensin-converting enzyme inhibitor induced imrovement in walking time in peripheral arterial disease patients. J Hypertens 26 (2008) 1037-1042
33. Hobbs S.D., Thomas M.E., and Bradbury A.W. Manipulation of the renin angiotensin system in peripheral arterial disease. Eur J Vasc Endovasc Surg 28 (2004) 573-582
34. Ueda S., Meredith P.A., Morton J., Connell J.M.C., and Elliot H.L. ACE (I/D) genotype as a predictor of the magnitude and duration of the response to an ACE inhibitor drug (Enaprilat) in humans. Circulation 98 (1999) 2148-2153
35. Kitsios G., and Zintzaras E. ACE (I/D) polymorphism and response to treatment in coronary artery disease: a comprehensive database and meta-analysis involving study quality evaluation. BMC Med Genet 10 (2009) 50