The health and toxic adverse effects of Fusarium fungal mycotoxin, fumonisins, on human population

American Journal of Infectious Diseases

Volumn 5, Issue 4, 2009, Pages 280-288

  Wan Norhasima, W M ^a,b   Abdulamir, A S ^a   Abu Bakar, F ^a   Son, R ^a   Norhafniza, A ^b  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

^b MALAYSIAN AGRICULTURAL RESEARCH AND DEVELOPMENT INSTITUTE MARDI   (Malaysia)

Author keywords

Fumonisin B1; Leukoencephalomalacia; Pulmonary edema; Toxicity

Indexed keywords

FUMONISIN; FUMONISIN B1; FUMONISIN B2; MYCOTOXIN;

AWARENESS; BIOSYNTHESIS; CARCINOGENESIS; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CLEANING; DETOXIFICATION; ECONOMIC ASPECT; EQUINE LEUKOENCEPHALOMALACIA; ESOPHAGUS CANCER; FOOD ANALYSIS; FOOD CONTAMINATION; FUSARIUM; HARVEST; HEALTH CARE COST; HEALTH HAZARD; HORSE DISEASE; HUMAN; HUMIDITY; LIVER TOXICITY; LIVESTOCK; LUNG EDEMA; MORTALITY; NEPHROTOXICITY; NONHUMAN; PHYSICAL CHEMISTRY; POPULATION EXPOSURE; REVIEW;

EID: 70649088943     PISSN: 15536203     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (60)

1. Gelderblom, W.C.A., K. Jaskiewicz, W.F.O. Marasas, P.G. Thiel, R.M. Horak, R. Vleggar and N.P. Kriek, 1988. Fumonisins-novel mycotoxins with cancer-promoting activity produced by Fusarium moniliforme. Applied Environ. Microbiol., 54: 1806-1811. http://aem.asm.org/cgi/content/abstract/54/7/1806
2. Weidenbörner, M., 2001. Foods and fumonisins. Eur. Food Res. Technol., 212: 262-273. DOI: 10.1007/s002170000259
3. Da Silva, J.B., C.R. Pozzi, M.A.B. Mallozzi, E.M. Ortega and B. Corrêa, 2000. Mycoflora and occurence of aflatoxin B1 and fumonisin B1 during storage of Brazilian sorghum. J. Agric. Food Chem., 48: 4352-4356. DOI: 10.1021/jf990054w
4. Tseng, T.C. and J.C. Tu, 1997. Mycoflora and mycotoxins in adzuki and mung beans produced in Ontario, Canada. Microbios, 90: 87-95. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Ret rieve&db= PubMed&dopt=Citation&list-uids=9345788
5. Martins, M.L., H.M. Martins and F. Bernando, 2001. Fumonisin B1 and B2 in black tea and medicinal plants. J. Food Protect., 64: 1268-1270. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db= PubMed&dopt=Citation&list-uids =11510675
6. Chelkowski, J., 1998 Distribution of Fusarium Species and Their Mycotoxins in Cereal Grains. In: Mycotoxins in Agriculture and Food Safety, Sinhaand, K.K. and D. Bhatnagar (Eds.). CRC Press, Marcel Dekker, New York, ISBN: 9780824701925, pp: 520.
7. Julian, A.M., P.W. Wareing, S.I. Phillips, V.F.P. Medlock, M.V. Macdonald and L.E. Del Rio, 1995. Fungal contamination and selected mycotoxins in pre-and post-harvest maize in Honduras. Mycopathologia, 129: 5-16. DOI: 10.1007/BF01139331
8. Marasas, W.F.O., T.S. Kellerman, W.C.A. Gelderblom, J.A.W. Coetzer, P.G. Thiel and J.J. Van Der Lugt, 1988. Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme. Onderstepoort J. Vet. Res., 55: 197-203. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db= PubMed&dopt=Citation&list-uids =3217091
9. Haschek, W.M., G. Motelin, D.K. Ness, K.S. Harlin, W.F. Hall, R.F. Vesonder, R.E. Peterson and V.R. Beasley, 1992. Characterization of fumonisin toxicity in orally and intravenously dosed swine. Mycopathologia, 117: 83-96. DOI: 10.1007/BF00497283
10. Rheeder, J.P., W.F.O. Marasas, P.G. Thiel, E.W. Syndenham, G.S. Shephard and D.J. Van Schalkwyk, 1992. Fusarium moniliforme and fumonisins in corn in relation to human esophageal cancer in Transkein. Phytopathology, 83: 353-357. DOI: 10.1094/Phyto-82-353
11. Scott, P.M., 1993. Fumonisin. Int. J. Food Microbiol., 18: 257-270. DOI: 10.1016/0168- 1605(93)90149-B
12. Blackwell, B.A., O.E. Edwards, J.W. Apsimon and A. Fruchier, 1995. Relative configuration of the C- 10 to C-16 fragment of fumonisin B1. Tetrahedron Lett., 36: 1973-1976. DOI: 10.1016/0040- 4039(95)00205-Q
13. Seo, J.A. and Y.W. Lee, 1999. Natural occurrence of the C series of fumonisins in moldy corn. Appl. Environ. Microbiol., 65: 1331-1334. http://aem.asm.org/cgi/content/full/65/3/1331
14. Musser, S.M. and R.D. Plattner, 1997. Fumonisin composition in cultures of Fusarium moniliforme, Fusarium proliferatum and Fusarium nygami. J. Agric. Food Chem., 45: 1169-1173. DOI: 10.1021/jf960663t (Pubitemid 127476886)
15. Howard, P.C., M.I. Churchwell, L.H. Couch, M.M. Marques and D.R. Doerge, 1998. Formation of N-(carboxymethyl)fumonisin B1, following the reaction of fumonisin B1 with reducing sugars,. J. Agric. Food Chem., 46: 3546-3557. DOI: 10.1021/jf980194q
16. Poling, S.M., R.D. Plattner and D.N. Weisleder, 2002. N-(1-Deoxy-D-fructos-1-yl) fumonisin B1 the initial reaction product of fumonisin B1 and D-glucose. J. Agric. Food Chem., 50: 1318-1324. DOI: 10.1021/jf010955g
17. Cawood, M.E., W.C.A. Gelderblom, R. Vleggaar, Y. Beh, P.G. Thiel and W.F.O. Marasas, 1991. Isolation of the fumonisin mycotoxins: A quantitative approach. J. Agric. Food Chem., 39: 1958-1962. DOI: 10.1021/jf00011a014
18. Ross, P.F., L.G. Rice, G.D. Osweiler, P.E. Nelson, J.L. Richard and T.M. Wilson, 1992. A review and update of animal toxicoses associated with fumonisin-contaminated feeds and production of fumonisins by Fusarium isolates. Mycopathologia, 117: 109-114. DOI: 10.1007/BF00497286
19. Musser, S.M., M.L. Gay and E.P. Mazzola, 1996. Identification of a new series of fumonisins containing 3-hydroxypyridine. J. Nat. Prod., 59: 970-972. DOI: 10.1021/np960349t
20. Sydenham, E.W., W.F.O. Marasas, G.S. Shephard, P.G. Thiel and E.Y. Hirooka, 1992. Fumonisin concentrations in Brazilian feeds associated with field outbreaks of confirmed and suspected animal mycotoxicoses. J. Agric. Food Chem. 40: 994-997. DOI: 10.1021/jf00018a016
21. Mirocha, C.J., C.G. Mackintosh, U.A. Mirza, W. Xie, Y. Xu and J. Chen, 1992. Occurrence of fumonisin in forage grass in New Zealand. Applied Environ. Microbiol., 58: 3196-3198. http://www.pubmedcentral.nih.gov/articlerender.fc gi?tool=pubmed&pubmedid=16348778
22. Ross, P.F., L.G. Rice, R.D. Plattner, T.M. Wilson and D.L. Owens, 1991. Concentrations of fumonisin B1 in feeds associated with animal health problems. Mycopathologia, 114: 129-135. DOI: 10.1007/BF00437200
23. Wilson, T.M., Ross. P.F., L.G. Rice, G.D. Osweiler and H.A. Nelson et al., 1990. Fumonisin B1 levels associated with an epizootic of equine leukoencephalomalacia. J. Vet. Diagn. Invest., 2: 213-216. http://jvdi.org/cgi/ reprint/2/3/213
24. Pittet, A., V. Parisod and M. Schellenberg, 1992. Occurrence of fumonisins B I and B 2 in corn-based products from the Swiss market. J. Agric. Food Chem., 40: 1352-1354. DOI: 10.1021/jf00020a012
25. Sydenham, E.W., G.S. Shephard, P.G. Thiel, W.F.O. Marasas and S. Stockenström, 1991. Fumonisin contamination of commercial corn-based human foodstuffs. J. Agric. Food Chem., 39: 2014-2018. DOI: 10.1021/jf00011a028
26. Sutton, J.C., 1982. Epidemiology of wheat head blight and maize ear rot caused by Fusarium graminearum. Can. J. Plant Pathol., 4: 195-209. http://www.cps-scp.ca/download/cjpp-archive/ Vol4/CJPP4(2)195-209(1982).pdf
27. Martin, R.A., J.A. Macleod and C. Caldwell, 1991. Influences of production imputs on incidence of infection by Fusarium species on cereal seed. Plant Dis., 75: 784-788. DOI: 10.1094/PD-75-0784
28. Duvik, J., 2001. Prospects for reducing fumonisin contamination of maize through genetic modification. Environ. Health Perspect., 109: 337-342. http://www.pubmedcentral.nih.gov/articlerender.fc gi?artid=1240685
29. Hammond, B.G., K.W. Campbell, C.D. Pilcher, T.A. Degoover and A.E. Robinson, 2004. Lower fumonisin mycotoxin levels in the grain of Bt corn grown in the United states in 2000-2002. J. Agric. Food Chem., 52: 1390-1397. DOI: 10.1021/jf030441c
30. Dawson, W.A.J.M., G.L. Baterman, J. Köhl, B.H. De Haas and C.H. Lombaers-Van Der Plas, "Controlling infection of cereal grain by toxigenic Fusarium species using fungal competitors. Proceeding of the BCPC Conference on Pests and Diseases, British Crop Protection Council, Nov. 2002, pp. 347-352. http://www.cababstractsplus.org/abstracts/Abstract. aspx?AcNo=20033026821
31. Schisler, D.A., N.I. Khan, M.J. Boehm and P.J. Slininger, 2002. Greenhouse and field evaluation of biological control of Fusarium head blight on durum wheat. Plant Dis., 86: 1350-1356. DOI: 10.1094/PDIS.2002.86.12.1350
32. Bacon, C.W., I.E. Yates, D.M. Hinton and M. Filmore, 2001. Biological control of Fusarium moniliforme in maize. Environ. Health Perspect., 109: 325-343. http://www.pubmedcentral.nih.gov/articlerender.fc gi?artid=1240683
33. Marin, S., N. Magan, N. Belli, A.J. Ramos, R. Canela and V. Sanchis, 1999. Two-dimensional profile of fumonisin B1 production by Fusarium moniliforme and Fusarium proliferatum in relation to environmental factors and potential for modelling toxin formation in maize grain. Int. J. Food Microbiol., 51: 159-167. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Ret rieve&db=PubMed&dopt=Citation&list-uids=10574091
34. Warfield, C.Y. and D.G. Gilchrist, 1999. Influence of kernel age on fumonisin B1 production in maize by Fusarium moniliforme. Applied Environ. Microbiol., 65: 2853-2856. http://aem.asm.org/cgi/content/full/65/7/2853
35. Cahagnier, B., D. Melcion and D. Richard-Molard, 1995. Growth of Fusarium moniliforme and its biosynthesis of fumonisin B1 on maize grain as a function of different water activities. Lett. Applied Microbiol., 20: 247-251. DOI: 10.1111/j.1472- 765X.1995.tb00439
36. Ono, E.Y., E.Y. Sasaki, E.H. Hashimoto, L.N. Hara, and B. Correa, 2002. Post-harvest storage of corn: Effect of beginning moisture content on mycoflora and fumonisin contamination. Food Addit. Contam., 19: 1081-1090. DOI: 10.1080/02652030210146828
37. Balzer, A., D. Tardieu, J.D. Bailly and P. Guerre, 2004. The trichothecenes: Toxins nature, natural occurrence in food and feeds and ways of struggle. Rev. Med. Vet., 155: 299-314. http://www.scopus.com/scopus/record/ display.ur l?view=basic&eid=2-s2.0- 4344586211&origin= resultslist&sort=plf-f&cite=2-s2.0- 4344586211&src=s&imp= t&sid=GTVGvNDRBRixlxY UgOkkOnA%3a110&sot=cite&sdt=a&sl=0
38. Vasanthi, S. and R.V. Bath, 1998. Mycotoxins in foods: Occurrence, health and economic significance and food control measures. Indian J. Med. Res., 108: 212-224. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db= PubMed&dopt=Citation&list-uids =9863277
39. Dupuy, J., P. Le Bars and H. Boudra, 1993. Thermostability of fumonisin B1, a mycotoxin from Fusarium moniliforme in corn. Applied Environ. Microbiol., 59: 2864-2867. http://aem.asm.org/cgi/content/abstract/59/9/2864
40. Park, J.W., P.M. Scott, B.P.Y. Lau and D.A. Lewis, 2004. Analysis of heat-processed corn foods for fumonisins and bound fumonisins,. Food Addit. Contam., 21: 1168-1178. DOI: 10.1080/02652030400021873
41. Scott, P.M. and G.A. Lawrence, 1994. Stability and problems in recovery of fumonisins added to corn-based foods. J. AOAC. Int., 77: 541-545. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Ret rieve&db= PubMed&dopt=Citation&list-uids=8199487
42. Castelo, M.M., S.S. Summer and L.B. Bullerman, 1998. Stability of fumonisins in thermally processed corn products. J. Food Prot., 61: 1030-1033. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db= PubMed&dopt=Citation&list-uids =9713766
43. Castelo, M.M. and L.B. Bullerman,2001. Reduction of fumonisin by the corn flake process. Proceeding of the AACC Annual Meeting, Oct. 14-18, AACC Press. http://www.aaccnet.org/meetings/2001/Abstracts/a 01ma362.htm
44. Saunders, D.S., F.I. Meredith and K.A. Voss, 2001. Control of fumonisin: Effect of processing. Environ. Health Perspect., 109: 333-336. http://www.ehponline.org/members/2001/suppl- 2/333-336saunders/saunders-full. html
45. Westlake, K., R.I. Mackie and M.F. Dutton, 1989. In vitro metabolism of mycotoxins by bacterial, protozoal and ovine ruminal fluid preparations. Anim. Feed Sci. Technol., 25: 169-178. DOI: 10.1016/0377-8401(89)90117-X
46. Wilson, T.M., Ross. P.F., D.L. Owens, L.G. Rice, S.A. Green, S.J. Jenkins and H.A. Nelson, 1992. Experimental reproduction of ELEM Mycophatologia, 117: 115-120. DOI: 10.1007/BF00497287
47. Motelin, G.K., W.M. Haschek, D.K. Ness and W.F. Hall, 1994. Temporal and dose-response features in swine fed corn screenings contaminated with fumonisin mycotoxins. Mycopathologia, 126: 27-40. DOI: 10.1007/BF01371170
48. Suzuki, C.A.M., L. Hierlihy, M. Barker, I. Curran, R. Mueller and G.S. Bondy, 1995. The effects of fumonisins on several markers of nephrotoxicity in rats. Toxicol. Applied Pharmacol., 133: 207-214. DOI: 10.1006/taap.1995.1143
49. Howard, P.C., R.M. Eppley, M.E. Stack and A. Warbritton, 2001. Fumonisin B1 carcinogenicity in a two-year feeding study using F344 rats and B63C3F1 mice. Environ. Health Perspect., 109: 277-282. http://www.ehponline.org/members/2001/ suppl- 2/277-282howard/howard-full.html
50. Gelderblom, W.C.A., N.P. Kriek, W.F.O. Marasas and P.G. Thiel, 1991. Toxicity and carcinogenicity of the Fusarium monilffbrme metabolite, fumonisin B I, in rats. Carcinogenesis, 12: 1247-1251. http://www.ncbi.nlm.nih.gov/entrez/ query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list-uids =1649015
51. Javed, T., G.A. Bennett, J.L. Richard, M.A. Dombrink-Kurtzman, L.M. Cote and W.A. Buck, 1993. Mortality in broiler chicks on feed amended with Fusarium proliferatum culture material or with purified fumonisin B1 and moniliformin. Mycopathologia, 123: 171-184 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list-uids =8302366
52. Carlson, D.B., D.E. Williams, J.M. Spitsbergen and P.F. Ross, 2001. Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitrosoguanidine-initiated liver tumors in rainbow trout. Toxicol. Appl. Pharmacol., 172: 29-36. DOI: 10.1006/taap.2001.9129
53. Howard, P.C., L.H. Couch, R.E. Patton, R.M. Eppley and D.R. Doerge, 2002. Comparison of the toxicity of several fumonisin derivatives in a 28-day feeding study with female B6C3F(1) mice. Toxicol. Applied Pharmacol., 185: 153-165. DOI: 10.1006/taap.2002.9529
54. Lemke, S., S.E. Ottinger, C.L. Ake, K. Mayura and T.D. Phillips, 2001. Deamination of the fumonisin B1 and biological assessment of reaction product toxicity. Chem. Res. Toxicol., 14: 11-15. DOI: 10.1021/tx000166d
55. Yoshizawa, T., A. Yamashita and Y. Luo, 1994. Fumonisin occurrence in corn from high- and low-risk areas for human esophageal cancer in China Applied Environ. Microbiol., 60: 1626-1629. http://aem.asm.org/cgi/reprint/60/5/1626
56. Marasas, W.F.O., 2001. Discovery and occurrence of the fumonisin: A historical perspective. Environ. Health Perspect., 109: 239-243. http://www.ehponline.org/members/2001/suppl- 2/239-243marasas/marasas-full.html
57. Hendricks, K., 1999. Fumonisins and neural tube defects in South Texas. Epidemiol., 10: 198-200. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cm d=Retrieve&db=PubMed&dopt=Citation&list-uids =10069261 (Pubitemid 29093962)
58. Voss, K.A., P.C. Howard, R.T. Riley, R.P. Sharma, T.J. Bucci and R.J. Lorentzen, 2002. Carcinogenicity and mechanism of action of fumonisin B1: A mycotoxin produced by Fusarium moniliforme. Cancer Detect. Prevent., 26: 1-9. DOI: 10.1016/S0361-090X(02)00011-9
59. Hussein, H.S. and M.B. Jeffrey, 2001. Toxicity, metabolism and impact of mycotoxins on humans and animals. Toxicology, 167: 101-134. DOI: 10.1016/S0300-483X(01)00471-1
60. Wu, F., 2007. Measuring the economic impacts of Fusarium toxins in animal feeds J. Anim. Feed Sci. Tech., 137: 363-374. DOI: 10.1016/j.anifeedsci.2007. 06.010